Computation In Cells And Tissues
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Computation In Cells And Tissues
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Author : R. Paton
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Computation In Cells And Tissues written by R. Paton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Computers categories.
The field of biologically inspired computation has coexisted with mainstream computing since the 1930s, and the pioneers in this area include Warren McCulloch, Walter Pitts, Robert Rosen, Otto Schmitt, Alan Turing, John von Neumann and Norbert Wiener. Ideas arising out of studies of biology have permeated algorithmics, automata theory, artificial intelligence, graphics, information systems and software design. Within this context, the biomolecular, cellular and tissue levels of biological organisation have had a considerable inspirational impact on the development of computational ideas. Such innovations include neural computing, systolic arrays, genetic and immune algorithms, cellular automata, artificial tissues, DNA computing and protein memories. With the rapid growth in biological knowledge there remains a vast source of ideas yet to be tapped. This includes developments associated with biomolecular, genomic, enzymic, metabolic, signalling and developmental systems and the various impacts on distributed, adaptive, hybrid and emergent computation. This multidisciplinary book brings together a collection of chapters by biologists, computer scientists, engineers and mathematicians who were drawn together to examine the ways in which the interdisciplinary displacement of concepts and ideas could develop new insights into emerging computing paradigms. Funded by the UK Engineering and Physical Sciences Research Council (EPSRC), the CytoCom Network formally met on five occasions to examine and discuss common issues in biology and computing that could be exploited to develop emerging models of computation.
Mechanics Of Biological Tissue
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Author : Gerhard A. Holzapfel
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-03
Mechanics Of Biological Tissue written by Gerhard A. Holzapfel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-03 with Science categories.
The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book points to important directions combining mechanical sciences with the new developments in biology. It delivers articles on mechanics of tissues at the molecular, cellular, tissue and organ levels.
Computational Biology For Stem Cell Research
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Author : Pawan Raghav
language : en
Publisher: Elsevier
Release Date : 2024-01-12
Computational Biology For Stem Cell Research written by Pawan Raghav and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-12 with Science categories.
Computational Biology for Stem Cell Research is an invaluable guide for researchers as they explore HSCs and MSCs in computational biology. With the growing advancement of technology in the field of biomedical sciences, computational approaches have reduced the financial and experimental burden of the experimental process. In the shortest span, it has established itself as an integral component of any biological research activity. HSC informatics (in silico) techniques such as machine learning, genome network analysis, data mining, complex genome structures, docking, system biology, mathematical modeling, programming (R, Python, Perl, etc.) help to analyze, visualize, network constructions, and protein-ligand or protein-protein interactions. This book is aimed at beginners with an exact correlation between the biomedical sciences and in silico computational methods for HSCs transplantation and translational research and provides insights into methods targeting HSCs properties like proliferation, self-renewal, differentiation, and apoptosis. - Modeling Stem Cell Behavior: Explore stem cell behavior through animal models, bridging laboratory studies to real-world clinical allogeneic HSC transplantation (HSCT) scenarios. - Bioinformatics-Driven Translational Research: Navigate a path from bench to bedside with cutting-edge bioinformatics approaches, translating computational insights into tangible advancements in stem cell research and medical applications. - Interdisciplinary Resource: Discover a single comprehensive resource catering to biomedical sciences, life sciences, and chemistry fields, offering essential insights into computational tools vital for modern research.
Principles Of Computational Cell Biology
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Author : Volkhard Helms
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-29
Principles Of Computational Cell Biology written by Volkhard Helms and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-29 with Medical categories.
Computational cell biology courses are increasingly obligatory for biology students around the world but of course also a must for mathematics and informatics students specializing in bioinformatics. This book, now in its second edition is geared towards both audiences. The author, Volkhard Helms, has, in addition to extensive teaching experience, a strong background in biology and informatics and knows exactly what the key points are in making the book accessible for students while still conveying in depth knowledge of the subject.About 50% of new content has been added for the new edition. Much more room is now given to statistical methods, and several new chapters address protein-DNA interactions, epigenetic modifications, and microRNAs.
Computational Modeling In Tissue Engineering
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Author : Liesbet Geris
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-30
Computational Modeling In Tissue Engineering written by Liesbet Geris and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-30 with Technology & Engineering categories.
One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling. The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone. For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself. In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.
The Computational Mechanics Of Bone Tissue
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Author : Jorge Belinha
language : en
Publisher: Springer Nature
Release Date : 2020-02-11
The Computational Mechanics Of Bone Tissue written by Jorge Belinha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-11 with Science categories.
This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.
Modelling Organs Tissues Cells And Devices
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Author : Socrates Dokos
language : en
Publisher: Springer
Release Date : 2017-03-08
Modelling Organs Tissues Cells And Devices written by Socrates Dokos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-08 with Technology & Engineering categories.
This book presents a theoretical and practical overview of computational modeling in bioengineering, focusing on a range of applications including electrical stimulation of neural and cardiac tissue, implantable drug delivery, cancer therapy, biomechanics, cardiovascular dynamics, as well as fluid-structure interaction for modelling of organs, tissues, cells and devices. It covers the basic principles of modeling and simulation with ordinary and partial differential equations using MATLAB and COMSOL Multiphysics numerical software. The target audience primarily comprises postgraduate students and researchers, but the book may also be beneficial for practitioners in the medical device industry.
Methods And Applications Of Computational Immunology
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Author : Victor Greiff
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-30
Methods And Applications Of Computational Immunology written by Victor Greiff and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-30 with categories.
Computational Epigenetics In Human Diseases Cell Differentiation And Cell Reprogramming Volume I
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Author : Jianzhong Su
language : en
Publisher: Frontiers Media SA
Release Date : 2021-02-24
Computational Epigenetics In Human Diseases Cell Differentiation And Cell Reprogramming Volume I written by Jianzhong Su and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-24 with Science categories.
Unconventional Computation And Natural Computation
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Author : Cristian S. Calude
language : en
Publisher: Springer
Release Date : 2015-08-07
Unconventional Computation And Natural Computation written by Cristian S. Calude and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-07 with Computers categories.
This book constitutes the refereed proceedings of the 14th International Conference on Unconventional Computation and Natural Computation, UCNC 2015, held in Auckland, New Zealand, in August/September 2015. The 16 revised full papers were carefully reviewed and selected from 38 submissions. The papers cover a wide range of topics including among others molecular (DNA) computing; quantum computing; optical computing; chaos computing; physarum computing; computation in hyperbolic spaces; collision-based computing; cellular automata; neural computation; evolutionary computation; swarm intelligence; nature-inspired algorithms; artificial immune systems; artificial life; membrane computing; amorphous computing; computational systems biology; genetic networks; protein-protein networks; transport networks; synthetic biology; cellular (in vivo) computing; and computations beyond the Turing model and philosophical aspects of computing.