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Modelling Organs Tissues Cells And Devices


Modelling Organs Tissues Cells And Devices
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Modelling Organs Tissues Cells And Devices


Modelling Organs Tissues Cells And Devices
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Author : Socrates Dokos
language : en
Publisher: Springer
Release Date : 2017-03-08

Modelling Organs Tissues Cells And Devices written by Socrates Dokos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-08 with Technology & Engineering categories.


This book presents a theoretical and practical overview of computational modeling in bioengineering, focusing on a range of applications including electrical stimulation of neural and cardiac tissue, implantable drug delivery, cancer therapy, biomechanics, cardiovascular dynamics, as well as fluid-structure interaction for modelling of organs, tissues, cells and devices. It covers the basic principles of modeling and simulation with ordinary and partial differential equations using MATLAB and COMSOL Multiphysics numerical software. The target audience primarily comprises postgraduate students and researchers, but the book may also be beneficial for practitioners in the medical device industry.



Principles And Technologies For Electromagnetic Energy Based Therapies


Principles And Technologies For Electromagnetic Energy Based Therapies
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Author : Punit Prakash
language : en
Publisher: Academic Press
Release Date : 2021-12-02

Principles And Technologies For Electromagnetic Energy Based Therapies written by Punit Prakash and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-02 with Technology & Engineering categories.


Principles and Technologies for Electromagnetic Energy Based Therapies covers the theoretical foundations of electromagnetic-energy based therapies, principles for design of practical devices and systems, techniques for in vitro and in vivo testing of devices, and clinical application examples of contemporary therapies employing non-ionizing electromagnetic energy. The book provides in-depth coverage of: pulsed electric fields, radiofrequency heating systems, tumor treating fields, and microwave heating technology. Devices and systems for electrical stimulation of neural and cardiac issue are covered as well. Lastly, the book describes and discusses issues that are relevant to engineers who develop and translate these technologies to clinical applications. Readers can access information on incorporation of preclinical testing, clinical studies and IP protection in this book, along with in-depth technical background for engineers on electromagnetic phenomena within the human body and selected therapies. It covers both engineering and biological/medical materials and gives a full perspective on electromagnetics therapies. Unique features include content on tumor treating fields and the development and translation of biomedical devices. - Provides in-depth technical background on electromagnetic energy-based therapies, along with real world examples on how to design devices and systems for delivering electromagnetic energy-based therapies - Includes guidance on issues that are relevant for translating the technology to the market, such as intellectual property, regulatory issues, and preclinical testing - Companion site includes COMSOL models, MATLAB code, and lab protocols



Lab On A Chip Fabrication And Application


Lab On A Chip Fabrication And Application
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Author : Margarita Stoytcheva
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-06-29

Lab On A Chip Fabrication And Application written by Margarita Stoytcheva and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-29 with Science categories.


The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and LOC application.



Human Organs On A Chip Technology


Human Organs On A Chip Technology
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Author : P.V. Mohanan
language : en
Publisher: Elsevier
Release Date : 2024-06-18

Human Organs On A Chip Technology written by P.V. Mohanan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-18 with Science categories.


Human Organs-on-a-Chip Technology focuses on the technology advancement from "organ-on-a-chip to "multi organs-on-a-chip to the newest stage of "human organs-on-a-chip. Chapters investigate the design, simulation studies, device development and application of microfluidic systems. They also offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research. - Explores organs-on-a-chip technology, from the basics, to advanced developments and existing challenges and recent research trends and applications - Reviews every aspect of microfluidic devices, including biological evaluation and targeted delivery - Includes the latest information on regulatory updates



Microfluidics And Multi Organs On Chip


Microfluidics And Multi Organs On Chip
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Author : P. V. Mohanan
language : en
Publisher: Springer Nature
Release Date : 2022-07-11

Microfluidics And Multi Organs On Chip written by P. V. Mohanan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-11 with Medical categories.


This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.



Introduction For Heart 3d Bioprinting Book 2


Introduction For Heart 3d Bioprinting Book 2
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date : 2024-05-18

Introduction For Heart 3d Bioprinting Book 2 written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-18 with Medical categories.


The realm of bioprinting, especially 3D bioprinting of complex organs such as the heart, is at the forefront of modern medical science. This book, "Introduction to Heart 3D Bioprinting - Introduction to Cell Biology and The 3D Bioprinting," serves as a comprehensive guide to understanding the intricate relationship between cell biology and the innovative field of 3D bioprinting. In the rapidly advancing field of bioprinting, the ability to create functional heart tissues and eventually whole organs holds immense promise for addressing the global shortage of donor organs and improving outcomes for patients with severe cardiovascular diseases. However, this ambition requires a profound understanding of cell biology, tissue engineering, and the bioprinting technologies that can bring these visions to reality. This book is divided into two primary sections. The first section delves into the fundamentals of cell biology, providing detailed insights into cellular mechanisms, structures, and processes that are crucial for anyone looking to explore or work in the field of bioprinting. Topics such as cytoskeleton regulation, cellular respiration, DNA replication, and stem cell biology are meticulously covered to lay a robust foundation for understanding how cells can be manipulated and utilized in bioprinting applications. It explores the techniques, materials, and technologies used to create three-dimensional biological structures. This section discusses the integration of cells into bioprinted constructs, the challenges of mimicking the complex architecture of the heart, and the innovative solutions being developed to overcome these hurdles. Together, these sections provide a detailed roadmap from the basic principles of cell biology to the cutting-edge applications of 3D bioprinting. Whether you are a student, researcher, or practitioner, this book aims to equip you with the knowledge and tools necessary to contribute to the exciting advancements in heart 3D bioprinting. I would like to express my gratitude to the countless researchers and pioneers in the fields of cell biology and bioprinting whose work has made this book possible. Their dedication to advancing science and medicine inspires us to push the boundaries of what is possible and strive for innovations that can transform lives.



Encyclopedia Of Bioinformatics And Computational Biology


Encyclopedia Of Bioinformatics And Computational Biology
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Author :
language : en
Publisher: Elsevier
Release Date : 2018-08-21

Encyclopedia Of Bioinformatics And Computational Biology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-21 with Medical categories.


Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases



Tissue Engineering Explained


Tissue Engineering Explained
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Author : Vaijayanthi Nayar
language : en
Publisher: Educohack Press
Release Date : 2025-01-03

Tissue Engineering Explained written by Vaijayanthi Nayar and has been published by Educohack Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-03 with Science categories.


"Tissue Engineering Explained" delves into the biomedical process of using cells and biochemical and physiochemical factors to restore, improve, maintain, or replace different types of biological tissues. We cover the history of tissue engineering, basic concepts, and its future prospects. Our book presents complex information in an easy-to-understand manner, supported by analytical data, graphs, and tables. We highlight the importance of tissue engineering in the medical field and its growing market value. This comprehensive guide is ideal for anyone looking to understand the intricacies of tissue engineering and its applications.



Human Based Systems For Translational Research


Human Based Systems For Translational Research
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Author : Robert Coleman
language : en
Publisher: Royal Society of Chemistry
Release Date : 2014-12-08

Human Based Systems For Translational Research written by Robert Coleman and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-08 with Science categories.


This book provides a history and discussion of the use of human tissues as an alternative to animal-based testing for assessing the efficacy and safety of new medicines. Beginning by providing a historical background to animal-based testing, this text then describes in detail the issues relating to access to human cells and tissue and the rules and regulations governing their use. The book illustrates what is currently possible in humanising medicines research and development, and suggests more rational and reliable means of developing safe and effective drugs for the future than those on which we currently rely. Early chapters establish the need to generate more data in human-derived test systems, and the need for resources such as tissue banks and standardised processes whilst highlighting the barriers that have prevented such developments so far. Subsequent chapters explore the alternatives to current animal toxicology studies, including stem cells and computational models, with balanced views of the technical challenges and opportunities these offer. In addition, useful information on computational methods and pharmacokinetics are included. This book is an essential read for anyone engaged in translational drug discovery who wishes to consolidate their understanding and broaden their awareness of the key issues involved in accessing primary human tissue and the advantages of doing so.



Encyclopedia Of Tissue Engineering And Regenerative Medicine


Encyclopedia Of Tissue Engineering And Regenerative Medicine
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-06-03

Encyclopedia Of Tissue Engineering And Regenerative Medicine written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-03 with Science categories.


Encyclopedia of Tissue Engineering and Regenerative Medicine, Three Volume Set provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the fields of tissue engineering and regenerative medicine Contains multimedia features, including hyperlinked references and further readings, cross-references and diagrams/images Represents the most comprehensive and exhaustive product on the market on the topic