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Computational Mathematics Modeling In Cancer Analysis


Computational Mathematics Modeling In Cancer Analysis
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Computational Mathematics Modeling In Cancer Analysis


Computational Mathematics Modeling In Cancer Analysis
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Author : Wenjian Qin
language : en
Publisher: Springer Nature
Release Date : 2023-10-07

Computational Mathematics Modeling In Cancer Analysis written by Wenjian Qin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-07 with Computers categories.


This volume LNCS 14243 constitutes the refereed proceedings of the Second International Workshop, CMMCA 2023, Held in Conjunction with MICCAI 2023, on October 8, 2023, in Vancouver, BC, Canada. The 17 full papers presented were carefully reviewed and selected from 25 submissions. The conference focuses on the discovery of cutting-edge techniques addressing trends and challenges in theoretical, computational, and applied aspects of mathematical cancer data analysis.



Computational Mathematics Modeling In Cancer Analysis


Computational Mathematics Modeling In Cancer Analysis
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Author : Wenjian Qin
language : en
Publisher: Springer Nature
Release Date : 2022-09-22

Computational Mathematics Modeling In Cancer Analysis written by Wenjian Qin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-22 with Computers categories.


This book constitutes the proceedings of the First Workshop on Computational Mathematics Modeling in Cancer Analysis (CMMCA2022), held in conjunction with MICCAI 2022, in Singapore in September 2022. Due to the COVID-19 pandemic restrictions, the CMMCA2022 was held virtually. DALI 2022 accepted 15 papers from the 16 submissions that were reviewed. A major focus of CMMCA2022 is to identify new cutting-edge techniques and their applications in cancer data analysis in response to trends and challenges in theoretical, computational and applied aspects of mathematics in cancer data analysis.



Computational Biology Of Cancer


Computational Biology Of Cancer
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Author : Dominik Wodarz
language : en
Publisher: World Scientific
Release Date : 2005

Computational Biology Of Cancer written by Dominik Wodarz and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.


- Provides an introduction to computational methods in cancer biology - Follows a multi-disciplinary approach



Multiscale Modeling Of Cancer


Multiscale Modeling Of Cancer
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Author : Vittorio Cristini
language : en
Publisher: Cambridge University Press
Release Date : 2010-09-09

Multiscale Modeling Of Cancer written by Vittorio Cristini and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-09 with Technology & Engineering categories.


Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.



Mathematical And Computational Oncology


Mathematical And Computational Oncology
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Author : George Bebis
language : en
Publisher: Springer Nature
Release Date : 2020-12-07

Mathematical And Computational Oncology written by George Bebis and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Computers categories.


This book constitutes the refereed proceedings of the Second International Symposium on Mathematical and Computational Oncology, ISMCO 2020, which was supposed to be held in San Diego, CA, USA, in October 2020, but was instead held virtually due to the COVID-19 pandemic. The 6 full papers and 4 short papers presented together with 1 invited talk were carefully reviewed and selected from 28 submissions. The papers are organized in topical sections named: statistical and machine learning methods for cancer research; mathematical modeling for cancer research; general cancer computational biology; and posters.



Mathematical Models Of Cancer And Different Therapies


Mathematical Models Of Cancer And Different Therapies
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Author : Regina Padmanabhan
language : en
Publisher: Springer Nature
Release Date : 2020-10-31

Mathematical Models Of Cancer And Different Therapies written by Regina Padmanabhan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-31 with Technology & Engineering categories.


This book provides a unified framework for various currently available mathematical models that are used to analyze progression and regression in cancer development, and to predict its dynamics with respect to therapeutic interventions. Accurate and reliable model representations of cancer dynamics are milestones in the field of cancer research. Mathematical modeling approaches are becoming increasingly common in cancer research, as these quantitative approaches can help to validate hypotheses concerning cancer dynamics and thus elucidate the complexly interlaced mechanisms involved. Even though the related conceptual and technical information is growing at an exponential rate, the application of said information and realization of useful healthcare devices are lagging behind. In order to remedy this discrepancy, more interdisciplinary research works and course curricula need to be introduced in academic, industrial, and clinical organizations alike. To that end, this book reformulates most of the existing mathematical models as special cases of a general model, allowing readers to easily get an overall idea of cancer dynamics and its modeling. Moreover, the book will help bridge the gap between biologists and engineers, as it brings together cancer dynamics, the main steps involved in mathematical modeling, and control strategies developed for cancer management. This also allows readers in both medical and engineering fields to compare and contrast all the therapy-based models developed to date using a single source, and to identify unexplored research directions.



Mathematical Models And Computer Simulations For Biomedical Applications


Mathematical Models And Computer Simulations For Biomedical Applications
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Author : Gabriella Bretti
language : en
Publisher: Springer Nature
Release Date : 2023-09-17

Mathematical Models And Computer Simulations For Biomedical Applications written by Gabriella Bretti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-17 with Mathematics categories.


Mathematical modelling and computer simulations are playing a crucial role in the solution of the complex problems arising in the field of biomedical sciences and provide a support to clinical and experimental practices in an interdisciplinary framework. Indeed, the development of mathematical models and efficient numerical simulation tools is of key importance when dealing with such applications. Moreover, since the parameters in biomedical models have peculiar scientific interpretations and their values are often unknown, accurate estimation techniques need to be developed for parameter identification against the measured data of observed phenomena. In the light of the new challenges brought by the biomedical applications, computational mathematics paves the way for the validation of the mathematical models and the investigation of control problems. The volume hosts high-quality selected contributions containing original research results as well as comprehensive papers and survey articles including prospective discussion focusing on some topical biomedical problems. It is addressed, but not limited to: research institutes, academia, and pharmaceutical industries.



Mathematical Models In Cancer Research


Mathematical Models In Cancer Research
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Author : T. E. Wheldon
language : en
Publisher: CRC Press
Release Date : 1988

Mathematical Models In Cancer Research written by T. E. Wheldon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Art categories.


Cancer research deals with all aspects of malignant transformation, tumour growth and the effects of treatment. Mathematical models enable quantitative representations of the changes affecting cell state and cell number. This book provides a review of the scope of mathematical modelling in cancer research, bringing together for the first time a group of related mathematical topics including multistage carcinogenesis, tumour growth kinetics, growth control, radiotherapy, chemotherapy and biological targeting in cancer treatment. Physicists and mathematicians interested in medical research, biomathematicians, biostatisticians, radiation and medical oncologists and experimental and theoretical biologists will welcome this critical review of mathematical modelling in cancer research. This book will also be of interest to clinicians, basic cancer scientists and physicists working in radiotherapy departments, and to postgraduate students on courses in oncology and subjects.



Spatiotemporal Modeling Of Cancer Immunotherapy


Spatiotemporal Modeling Of Cancer Immunotherapy
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Author : William E. Schiesser
language : en
Publisher: Springer
Release Date : 2019-05-30

Spatiotemporal Modeling Of Cancer Immunotherapy written by William E. Schiesser and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-30 with Medical categories.


The focus of this book is a detailed discussion of a dual cancer vaccine (CV)-immune checkpoint inhibitor (ICI) mathematical model formulated as a system of partial differential equations (PDEs) defining the spatiotemporal distribution of cells and biochemicals during tumor growth. A computer implementation of the model is discussed in detail for the quantitative evaluation of CV-ICI therapy. The coding (programming) consists of a series of routines in R, a quality, open-source scientific computing system that is readily available from the internet. The routines are based on the method of lines (MOL), a general PDE algorithm that can be executed on modest computers within the basic R system. The reader can download and use the routines to confirm the model solutions reported in the book, then experiment with the model by varying the parameters and modifying/extending the equations, and even studying alternative models with the PDE methodology demonstrated by the CV-ICI model. Spatiotemporal Modeling of Cancer Immunotherapy: Partial Differential Equation Analysis in R facilitates the use of the model, and more generally, computer- based analysis of cancer immunotherapy mathematical models, as a step toward the development and quantitative evaluation of the immunotherapy approach to the treatment of cancer. To download the R routines, please visit: http://www.lehigh.edu/~wes1/ci_download



Mathematical Methods For Cancer Evolution


Mathematical Methods For Cancer Evolution
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Author : Takashi Suzuki
language : en
Publisher: Springer
Release Date : 2017-06-13

Mathematical Methods For Cancer Evolution written by Takashi Suzuki and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-13 with Mathematics categories.


The purpose of this monograph is to describe recent developments in mathematical modeling and mathematical analysis of certain problems arising from cell biology. Cancer cells and their growth via several stages are of particular interest. To describe these events, multi-scale models are applied, involving continuously distributed environment variables and several components related to particles. Hybrid simulations are also carried out, using discretization of environment variables and the Monte Carlo method for the principal particle variables. Rigorous mathematical foundations are the bases of these tools.The monograph is composed of four chapters. The first three chapters are concerned with modeling, while the last one is devoted to mathematical analysis. The first chapter deals with molecular dynamics occurring at the early stage of cancer invasion. A pathway network model based on a biological scenario is constructed, and then its mathematical structures are determined. In the second chapter mathematical modeling is introduced, overviewing several biological insights, using partial differential equations. Transport and gradient are the main factors, and several models are introduced including the Keller‒Segel systems. The third chapter treats the method of averaging to model the movement of particles, based on mean field theories, employing deterministic and stochastic approaches. Then appropriate parameters for stochastic simulations are examined. The segment model is finally proposed as an application. In the fourth chapter, thermodynamic features of these models and how these structures are applied in mathematical analysis are examined, that is, negative chemotaxis, parabolic systems with non-local term accounting for chemical reactions, mass-conservative reaction-diffusion systems, and competitive systems of chemotaxis. The monograph concludes with the method of the weak scaling limit applied to the Smoluchowski‒Poisson equation.