Computational Systems Biology Of Synaptic Plasticity
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Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement
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Author : Don Kulasiri
language : en
Publisher: #N/A
Release Date : 2017-06-09
Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement written by Don Kulasiri and has been published by #N/A this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-09 with Science categories.
This book demonstrates the power of mathematical thinking in understanding the biological complexity that exists within the brain. It looks at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology. Discussion then focusses on developments in computational models based on networks linked to synaptic plasticity. The models are used to understand memory formation and impairment and they provide a mathematical basis for memory research.Computational Systems Biology of Synaptic Plasticity is a valuable source of knowledge to postgraduate students and researchers in computational systems biology, and as a reference book for various techniques that are needed in modelling biological processes.
Computational Systems Biology Of Synaptic Plasticity
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Author : Don Kulasiri
language : en
Publisher:
Release Date : 2017
Computational Systems Biology Of Synaptic Plasticity written by Don Kulasiri and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with NATURE categories.
Computational Systems Biology
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Author : Andres Kriete
language : en
Publisher: Academic Press
Release Date : 2013-11-26
Computational Systems Biology written by Andres Kriete and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-26 with Science categories.
This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
Computational Methods In Systems Biology
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Author : Muffy Calder
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-05
Computational Methods In Systems Biology written by Muffy Calder and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-05 with Computers categories.
This book constitutes the refereed proceedings of the International Conference on Computational Methods in Systems Biology, CMSB 2007, held in Edinburgh, Scotland, September 2007. The 16 revised full papers presented present a variety of techniques from computer science, such as language design, concurrency theory, software engineering, and formal methods, for biologists, physicists, and mathematicians interested in the systems-level understanding of cellular processes.
Proceedings Of 11th International Conference On Alzheimers Disease Dementia 2018
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Author : ConferenceSeries
language : en
Publisher: ConferenceSeries
Release Date :
Proceedings Of 11th International Conference On Alzheimers Disease Dementia 2018 written by ConferenceSeries and has been published by ConferenceSeries this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
May 24-25, 2018 | Vienna | Austria Key Topics : Dementia-an underlying disease, Symptoms and Diagnosis of Dementia, Vascular Dementia, Alzheimer’s Diagnosis and Symptoms, Alzheimer’s Imaging and Clinical trials, Alzheimer’s Pathophysiology, Parkinson’s disease, Dementia with Lewy bodies, Frontotemporal dementia, Wernicke-Korsakoff Syndrome, Amyloid Protein in Dementia, Neurocognitive Disorder, Dementia Care Practice & Awareness, Therapeutic Targets & Mechanisms for Treatment, Animal Models & Translational Medicine, Mixed Dementia, Alzheimer’s Disease and Dementia Natural Remedies,
Synaptic Plasticity In Neurodegenerative Disorders
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Author : Sangeeta Singh
language : en
Publisher: CRC Press
Release Date : 2024-12-24
Synaptic Plasticity In Neurodegenerative Disorders written by Sangeeta Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Science categories.
This book explores the pivotal role of synaptic plasticity in the pathogenesis, progression, and potential treatment of neurodegenerative disorders. The initial chapter provides an in-depth understanding of the complexity and impact of neurodegenerative conditions. It discusses the association of mitochondrial dysfunction, epigenetic influences, and neuroinflammation with synaptic plasticity in neurodegenerative diseases. The following chapters review the dynamic changes that occur at the cellular and synaptic levels in Parkinson's disease, Alzheimer's disease, and Huntington's disease, paving the way for innovative therapeutic strategies. Furthermore, the book presents various computational tools and methodologies essential for enhancing our understanding of synaptic plasticity. It examines the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases. Discusses the role of synaptic plasticity in neurodegenerative diseases, shedding light on how dynamic changes occur at the cellular and synaptic levels Explores the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases Provides a comprehensive overview of neurodegenerative disorders, including pathogenesis, etiology, and treatment strategies Presents tools and techniques used to simulate the complex system biology of synaptic plasticity Examines the role of computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis Toward the end, the book explores the role of synaptic impairment and computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis. With its multifaceted approach, this book serves as a useful resource for researchers, clinicians, and students in the fields of neuroscience, computational biology, and neurology.
Computational Systems Neurobiology
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Author : N. Le Novère
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-20
Computational Systems Neurobiology written by N. Le Novère and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-20 with Medical categories.
Computational neurosciences and systems biology are among the main domains of life science research where mathematical modeling made a difference. This book introduces the many different types of computational studies one can develop to study neuronal systems. It is aimed at undergraduate students starting their research in computational neurobiology or more senior researchers who would like, or need, to move towards computational approaches. Based on their specific project, the readers would then move to one of the more specialized excellent textbooks available in the field. The first part of the book deals with molecular systems biology. Functional genomics is introduced through examples of transcriptomics and proteomics studies of neurobiological interest. Quantitative modelling of biochemical systems is presented in homogeneous compartments and using spatial descriptions. A second part deals with the various approaches to model single neuron physiology, and naturally moves to neuronal networks. A division is focused on the development of neurons and neuronal systems and the book closes on a series of methodological chapters. From the molecules to the organ, thinking at the level of systems is transforming biology and its impact on society. This book will help the reader to hop on the train directly in the tank engine.
Systems Biology
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Author : Aleš Prokop
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-08-28
Systems Biology written by Aleš Prokop and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-28 with Medical categories.
Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing patent protection or being withdrawn from the market are simply not being replaced by new therapies – the pharmaceutical market model is no longer functioning effectively and most pharmaceutical companies are failing to produce the innovation needed for success. This multi-authored new book looks at a vital strategy which can bring innovation to a market in need of new ideas and new products: Systems Biology (SB). Modeling is a significant task of systems biology. SB aims to develop and use efficient algorithms, data structures, visualization and communication tools to orchestrate the integration of large quantities of biological data with the goal of computer modeling. It involves the use of computer simulations of biological systems, such as the networks of metabolites comprise signal transduction pathways and gene regulatory networks to both analyze and visualize the complex connections of these cellular processes. SB involves a series of operational protocols used for performing research, namely a cycle composed of theoretical, analytic or computational modeling to propose specific testable hypotheses about a biological system, experimental validation, and then using the newly acquired quantitative description of cells or cell processes to refine the computational model or theory.
Transactions On Computational Systems Biology Iv
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Author : Luca Cardelli
language : en
Publisher: Springer
Release Date : 2006-03-09
Transactions On Computational Systems Biology Iv written by Luca Cardelli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-09 with Computers categories.
This, the 4th Transactions on Computational Systems Biology volume, contains carefully selected and enhanced contributions presented at the first Converging Science conference held at the University of Trento, Italy, in December 2004. Dedicated especially to models and metaphors from biology to bioinformatics tools, the 11 papers selected for the special issue cover a wide range of bioinformatics research, such as foundations of global computing, interdisciplinarity in innovation initiatives, biodiversity, and more.
Systems Biology And In Depth Applications For Unlocking Diseases
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Author : Babak Sokouti
language : en
Publisher: Elsevier
Release Date : 2024-11-05
Systems Biology And In Depth Applications For Unlocking Diseases written by Babak Sokouti and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-05 with Science categories.
Systems Biology and In-Depth Applications for Unlocking Diseases provides the essence of systems biology approaches in a practical manner illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment.Systematically written in 4 parts, this book first provides an introduction and history of systems biology; second, it provides the tools and resources needed for the structure and function of biological systems; next, it provides the evidence of systems biology in action to better understand disease connections; and finally, it provides the extensions of systems biology in various scientific fields including pharmacology, immunology, vaccinology, neuroscience, virology, and medicine. Examples include big data techniques, scale networks, mathematical model development, and much more.This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians, whether needed for immediate application or for building a comprehensive understanding of the field. - Provides detailed and comprehensive coverage of the field of systems biology - Delivers instruction on how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment - Makes effective steps towards personalized medicine in the treatment of disease - Explains effective disease treatment strategies at early diagnosis stages