Synaptic Plasticity In Neurodegenerative Disorders
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Synaptic Plasticity In Neurodegenerative Disorders
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Author : Sangeeta Singh
language : en
Publisher: CRC Press
Release Date : 2024-12-24
Synaptic Plasticity In Neurodegenerative Disorders written by Sangeeta Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Science categories.
This book explores the pivotal role of synaptic plasticity in the pathogenesis, progression, and potential treatment of neurodegenerative disorders. The initial chapter provides an in-depth understanding of the complexity and impact of neurodegenerative conditions. It discusses the association of mitochondrial dysfunction, epigenetic influences, and neuroinflammation with synaptic plasticity in neurodegenerative diseases. The following chapters review the dynamic changes that occur at the cellular and synaptic levels in Parkinson's disease, Alzheimer's disease, and Huntington's disease, paving the way for innovative therapeutic strategies. Furthermore, the book presents various computational tools and methodologies essential for enhancing our understanding of synaptic plasticity. It examines the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases. Discusses the role of synaptic plasticity in neurodegenerative diseases, shedding light on how dynamic changes occur at the cellular and synaptic levels Explores the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases Provides a comprehensive overview of neurodegenerative disorders, including pathogenesis, etiology, and treatment strategies Presents tools and techniques used to simulate the complex system biology of synaptic plasticity Examines the role of computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis Toward the end, the book explores the role of synaptic impairment and computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis. With its multifaceted approach, this book serves as a useful resource for researchers, clinicians, and students in the fields of neuroscience, computational biology, and neurology.
Translational Research In Traumatic Brain Injury
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Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2016-04-21
Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Homeostatic Synaptic Plasticity From Synaptic Circuit Assembly To Neurological Disorders
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Author : Lorenzo A. Cingolani
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-08
Homeostatic Synaptic Plasticity From Synaptic Circuit Assembly To Neurological Disorders written by Lorenzo A. Cingolani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-08 with Science categories.
Synaptic Plasticity And The Mechanism Of Alzheimer S Disease
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Author : Dennis J. Selkoe
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-01-08
Synaptic Plasticity And The Mechanism Of Alzheimer S Disease written by Dennis J. Selkoe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-08 with Medical categories.
A biochemical hypothesis - that Alzheimer’s disease (AD) is a progressive cerebral amyloidosis caused by the aggregation of the amyloid b-protein (Ab) - preceded and enabled the discovery of etiologies. This volume serves as a record focused on bringing together investigators at the forefront of elucidating the structure and function of hippocampal synapses with investigators focused on understanding how early assemblies of Ab may compromise some of these synapses.
The Cambridge Handbook Of Successful Aging
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Author : Rocío Fernández-Ballesteros
language : en
Publisher: Cambridge University Press
Release Date : 2019-01-24
The Cambridge Handbook Of Successful Aging written by Rocío Fernández-Ballesteros and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with Psychology categories.
Recent studies show that more people than ever before are reaching old age in better health and enjoying that health for a longer time. This Handbook outlines the latest discoveries in the study of aging from bio-medicine, psychology, and socio-demography. It treats the study of aging as a multidisciplinary scientific subject, since it requires the interplay of broad disciplines, while offering high motivation, positive attitudes, and behaviors for aging well, and lifestyle changes that will help people to stay healthier across life span and in old age. Written by leading scholars from various academic disciplines, the chapters delve into the most topical aspects of aging today - including biological mechanisms of aging, aging with health, active and productive aging, aging with satisfaction, aging with respect, and aging with dignity. Aimed at health professionals as well as general readers, this Cambridge Handbook offers a new, positive approach to later life.
Synaptic Plasticity
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Author : M. Baudry
language : en
Publisher: MIT Press
Release Date : 1993
Synaptic Plasticity written by M. Baudry and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
An up-to-date overview of the current status of research on the full scope of synaptic plasticity, including synaptic remodeling in response to damage, long-term depression and long-term potentiation, and learning and memory.Synaptic Plasticity presents an up-to-date overview of the current status of research on the full scope of synaptic plasticity, including synaptic remodeling in response to damage, long-term depression and long-term potentiation, and learning and memory. The contributions are written by leading experts in the field and cover approaches from biochemical, anatomical, physiological, behavioral, and computational levels. They offer hypotheses concerning the molecular and cellular mechanisms that are responsible for the various manifestations of synaptic plasticity and propose models explaining how these cellular events can be linked to the functional and behavioral expressions of these adaptive principles. ContentsIntroduction - Molecular Correlates of Activity-dependent Development and Synaptic Plasticity, S. Hockfield - Molecular Sorting in Neurons, 0. Steward - Molecular and Morphological Responses to Deafferentation in Rodents, C. E. Finch, T. H. McNeill - Forms of Long-term Potentiation Induced by NMDA and Non-NMDA Receptor Activation, T. Teyler, L. Grover - Long-term Potentiation: Biochemical Mechanisms, M. Baudry, G. Lynch - Cerebellar Mechanisms of Long-Term Depression, M. Ito - Long-term Depression: Related Mechanisms in Cerebellum, Neocortex, and Hippocampus, A. Artola, W. Singer - Theory of Synaptic Plasticity in Visual Cortex, N. Intrator, M. F. Bear, L. N. Cooper, M. A. Paradiso - A Theoretical and Experimental Strategy for Realizing a Biologically Based Model of the Hippocampus, T. W. Berger et al - Synaptic Plasticity, Learning, and Memory, S. P. Rose - Synaptic Plasticity and Memory Storage, R. F. Thompson et al
Cellular And Molecular Mechanisms Of Synaptic Plasticity At Hippocampal And Cortical Synapses
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Author : Roberto De Pasquale
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-11
Cellular And Molecular Mechanisms Of Synaptic Plasticity At Hippocampal And Cortical Synapses written by Roberto De Pasquale and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-11 with Science categories.
Small Molecules In Neurodegeneration
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Author : Nawab John Dar
language : en
Publisher: CRC Press
Release Date : 2025-03-13
Small Molecules In Neurodegeneration written by Nawab John Dar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-13 with Medical categories.
Neurodegenerative diseases, like Alzheimer's, Parkinson's, and Huntington's, cast a long shadow over millions of lives, stealing memories, independence, and futures. The rising tide of these age-related disorders threatens to overwhelm healthcare systems worldwide, prompting an urgent search for effective treatments. While current options offer temporary relief, they fail to halt the relentless march of these devastating conditions. However, a beacon of hope shines at the intersection of cutting-edge neuroscience and the world of small molecules. These tiny chemical warriors, with their inherent advantages of cost-effectiveness, scalability, and diverse functionalities, are emerging as powerful weapons in the fight against neurodegeneration. This book stands as a testament to this increasing revolution. It investigates deep into the intricacies of small molecules, exploring their potential to unravel the mysteries of neurodegenerative diseases and pave the way for innovative therapeutic interventions. Key Features: Provides a comprehensive and accessible overview of the emerging field of small molecules in neurodegenerative diseases. Bridges the gap in current literature by addressing the specific impact of small molecules on these devastating conditions. Offers an in-depth exploration of the various mechanisms by which small molecules can combat neurodegeneration. Serves as a valuable resource for a wide audience, from students to professionals in the field. Lays the foundation for a deeper understanding of neurodegenerative diseases and unlocks new avenues for the development of effective therapies.
Synaptic Plasticity
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Author : Michel Baudry
language : en
Publisher: CRC Press
Release Date : 2005-04-12
Synaptic Plasticity written by Michel Baudry and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-12 with Medical categories.
This reference provides a clear understanding of the basic mechanisms of synaptic transmission and information processing and illustrates potential clinical applications for the recovery of lost function as a result of gene defects, injury, or disease-relating the most recent advances in the design of new therapeutics, the treatment of neurological
Nutraceutical Fruits And Foods For Neurodegenerative Disorders
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Author : Raj K. Keservani
language : en
Publisher: Elsevier
Release Date : 2023-11-21
Nutraceutical Fruits And Foods For Neurodegenerative Disorders written by Raj K. Keservani and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-21 with Technology & Engineering categories.
Nutraceutical Fruits and Foods for Neurodegenerative Disorders presents food-based strategies, specifically related to nutraceuticals, in delaying the onset and slowing down of the propensity of neuronal devastation. In addition to highlighting the positive effects of nutraceutical fruits and foods on brain health, the book also explores the medicinal properties of fruits, vegetables, berries and nutraceuticals, along with their contribution to environmental factors, potential hazards and the need for specific regulatory actions. This book will be a welcomed reference for nutrition researchers, dieticians, nutritionists and academicians studying related fields. - Presents the positive aspects of nutraceutical fruits and food effect on brain health - Highlights the structure activity relationship of constituents present in nutraceuticals in the treatment and cure of neurodegenerative diseases - Explores the nuances of novelty in dosage form design, production, authentication, quality control and market authorization of nutraceuticals