Computer Simulation In Cell Radiobiology

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Computer Simulation In Cell Radiobiology

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Author : Andrej Yu. Yakovlev
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Computer Simulation In Cell Radiobiology written by Andrej Yu. Yakovlev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Mathematics categories.

This research monograph demonstrates the possible ways of using stochastic simulation for exploring cell kinetics, emphasising the effects of cell radiobiology. In vitro kinetics of normal and irradiated cells is the main subject, but some approaches to the simulation of controlled cell systems are considered as well: the epithelium of the small intestine in mice taken as a case in point. Of particular interest is the evaluation of simulation modelling as a tool for gaining insight into biological processes and hence the new inferences from concrete experimental data, concerning regularities in cell population response to irradiation. The book is intended to stimulate interest among computer science specialists in developing new, more efficient means for the simulation of cell systems and to help radiobiologists in interpreting the experimental data. The reader is expected to be acquainted with fundamentals of the theory of probability and stochastic processes. Applications are addressed to a biologically educated reader.

International Journal Of Radiation Biology And Related Studies In Physics Chemistry And Medicine

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Author :
language : en
Publisher:
Release Date : 1991

International Journal Of Radiation Biology And Related Studies In Physics Chemistry And Medicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with categories.

Radiobiology For The Radiologist

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Author : Eric J. Hall
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2012-03-28

Radiobiology For The Radiologist written by Eric J. Hall and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-28 with Medical categories.

In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.

Transient Processes In Cell Proliferation Kinetics

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Author : Andrej Yu. Yakovlev
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08

Transient Processes In Cell Proliferation Kinetics written by Andrej Yu. Yakovlev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Mathematics categories.

A mathematician who has taken the romantic decision to devote himself to biology will doubtlessly look upon cell kinetics as the most simple and natural field of application for his knowledge and skills. Indeed, the thesaurus he is to master is not so complicated as, say, in molecular biology, the structural elements of the system, i. e. ceils, have been segregated by Nature itself, simple considerations of balance may be used for deducing basic equations, and numerous analogies in other areas of science also superficial add to one"s confidence. Generally speaking, this number of impression is correct, as evidenced by the very great theoretical studies on population kinetics, unmatched in other branches of mathematical biology. This, however, does not mean that mathematical theory of cell systems has traversed in its development a pathway free of difficulties or errors. The seeming ease of formalizing the phenomena of cell kinetics not infrequently led to the appearance of mathematical models lacking in adequacy or effectiveness from the viewpoint of applications. As in any other domain of science, mathematical theory of cell systems has its own intrinsic logic of development which, however, depends in large measure on the progress in experimental biology. Thus, during a fairly long period running into decades activities in that sphere were centered on devising its own specific approaches necessitated by new objectives in the experimental in vivo and in vitro investigation of cell population kinetics in different tissues.

International Journal Of Radiation Biology

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Author :
language : en
Publisher:
Release Date : 2004

International Journal Of Radiation Biology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.

National Library Of Medicine Current Catalog

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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1988

National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medicine categories.

Biomathematical Problems In Optimization Of Cancer Radiotherapy

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Author : A.Y. Yakovlev
language : en
Publisher: CRC Press
Release Date : 2020-11-25

Biomathematical Problems In Optimization Of Cancer Radiotherapy written by A.Y. Yakovlev and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Health & Fitness categories.

Biomathematical Problems in Optimization of Cancer Radiotherapy provides insight into the role of cell population heterogeneity in the optimal control of fractionated irradiation of tumors. The book emphasizes the mathematical modeling aspect of the problem and presents the state of the art in the stochastic description of irradiated cell survival. Some of the results are of general theoretical interest and can be applied to other areas of optimal control methodology. Detailed explanations of all mathematical statements are provided throughout the text. The book is excellent for biomathematicians, radiotherapists, oncologists, health physicists, and other researchers and students interested in the topic.

Advances In Mathematical Population Dynamics Molecules Cells And Man Proceedings Of The 4th International Conference On Mathematical Population Dynamics

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Author : O Arino
language : en
Publisher: World Scientific
Release Date : 1997-12-04

Advances In Mathematical Population Dynamics Molecules Cells And Man Proceedings Of The 4th International Conference On Mathematical Population Dynamics written by O Arino and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-12-04 with Mathematics categories.

This book presents a new approach to the subject of cosmology. It fully exploits Einstein's theory of general relativity. It is found that the most general formal expression of the theory replaces the (10-component) tensor formalism with a (16-component) quaternion formalism. This leads to a unified field theory, where one field incorporates gravitation and electromagnetism. The theory predicts an oscillating universe cosmology with a spiral configuration. Dark matter is explained in terms of a sea of particle-antiparticle pairs, each in a particular (derived) ground state. This leads to an explanation for the separation between matter and antimatter in the universe. There is a brief discussion of black holes and pulsars. The final chapter delves into philosophical considerations such as the different types of ‘truth’, positivism versus realism and a discussion of the role of the Mach principle in physics and cosmology./a

Computational Approaches In Molecular Radiation Biology

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Author : Matesh N. Varma
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Computational Approaches In Molecular Radiation Biology written by Matesh N. Varma and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.

The Office of Health and Environmental Research (OHER) has supported and continues to support development of computational approaches in biology and medicine. OHER's Radiological and Chemical Physics Program initiated development of computational approaches to determine the effects produced by radiation of different quality (such as high energy electrons, protons, helium and other heavy ions, etc. ) in a variety of materials of biological interest-such as water, polymers and DNA; these include molecular excitations and sub-excitations and the production of ionization and their spatial and temporal distribution. In the past several years, significant advances have been made in computational methods for this purpose. In particular, codes based on Monte Carlo techniques have ·been developed that provide a realistic description of track-structure produced by charged particles. In addition, the codes have become sufficiently sophisticated so that it is now possible to calculate the spatial and temporal distribution of energy deposition patterns in small volumes of subnanometer and nanometer dimensions. These dimensions or resolution levels are relevant for our understanding of mechanisms at the molecular level by which radiations affect biological systems. Since the Monte Carlo track structure codes for use in radiation chemistry and radiation biology are still in the developmental stage, a number of investigators have been exploring different strategies for improving these codes.

Statistical Modeling For Biological Systems

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Author : Anthony Almudevar
language : en
Publisher: Springer Nature
Release Date : 2020-03-11

Statistical Modeling For Biological Systems written by Anthony Almudevar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-11 with Medical categories.

This book commemorates the scientific contributions of distinguished statistician, Andrei Yakovlev. It reflects upon Dr. Yakovlev’s many research interests including stochastic modeling and the analysis of micro-array data, and throughout the book it emphasizes applications of the theory in biology, medicine and public health. The contributions to this volume are divided into two parts. Part A consists of original research articles, which can be roughly grouped into four thematic areas: (i) branching processes, especially as models for cell kinetics, (ii) multiple testing issues as they arise in the analysis of biologic data, (iii) applications of mathematical models and of new inferential techniques in epidemiology, and (iv) contributions to statistical methodology, with an emphasis on the modeling and analysis of survival time data. Part B consists of methodological research reported as a short communication, ending with some personal reflections on research fields associated with Andrei and on his approach to science. The Appendix contains an abbreviated vitae and a list of Andrei’s publications, complete as far as we know. The contributions in this book are written by Dr. Yakovlev’s collaborators and notable statisticians including former presidents of the Institute of Mathematical Statistics and of the Statistics Section of the AAAS. Dr. Yakovlev’s research appeared in four books and almost 200 scientific papers, in mathematics, statistics, biomathematics and biology journals. Ultimately this book offers a tribute to Dr. Yakovlev’s work and recognizes the legacy of his contributions in the biostatistics community.