Control Of Cancer Cell Invasion By Nuclear Deformability
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Control Of Cancer Cell Invasion By Nuclear Deformability
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Author : Marina Krause-Vortmeyer
language : en
Publisher:
Release Date : 2015
Control Of Cancer Cell Invasion By Nuclear Deformability written by Marina Krause-Vortmeyer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Cancer Biology And The Nuclear Envelope
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Author : Eric C. Schirmer
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-02-22
Cancer Biology And The Nuclear Envelope written by Eric C. Schirmer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-22 with Medical categories.
"Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer."
Physics Of Cancer
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Author : Claudia Mierke
language : en
Publisher: Iph001
Release Date : 2018-10-24
Physics Of Cancer written by Claudia Mierke and has been published by Iph001 this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-24 with Science categories.
This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.
The Biology Of Cancer
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Author : Weinberg, Robert A.
language : en
Publisher: W.W. Norton & Company
Release Date : 2013-05-24
The Biology Of Cancer written by Weinberg, Robert A. and has been published by W.W. Norton & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Science categories.
Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.
The Physics Of Cancer
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Author : Caterina A. M. La Porta
language : en
Publisher: Cambridge University Press
Release Date : 2017-04-20
The Physics Of Cancer written by Caterina A. M. La Porta and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-20 with Science categories.
An introduction to the emerging field of cancer physics, integrating cancer biology with approaches from theoretical and applied physics.
Mechanotransduction
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Author :
language : en
Publisher: Academic Press
Release Date : 2014-07-29
Mechanotransduction written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-29 with Science categories.
Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. Volume 126 features in-depth reviews that focus on the tools required to investigate mechanotransduction. Additional chapters focus on how we can use these tools to answer fundamental questions about the interaction of physical forces with cell biology, morphogenesis, and function of mature structures. Chapters in the volume are authored by a unique combination of cell biologists and engineers, providing a range of perspectives on mechanotransduction. Provides a unique combination of perspectives from biologists and engineers Engaging to people of many training backgrounds
Molecular And Cellular Mechanobiology
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Author : Shu Chien
language : en
Publisher: Springer
Release Date : 2016-08-10
Molecular And Cellular Mechanobiology written by Shu Chien and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-10 with Medical categories.
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.
The Unfolded Protein Response In Cancer
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Author : Robert Clarke
language : en
Publisher: Springer
Release Date : 2019-03-01
The Unfolded Protein Response In Cancer written by Robert Clarke and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-01 with Medical categories.
This volume presents state-of-the-art information on each of the arms of the unfolded protein response (UPR), how their activation/repression are regulated, integrated, and coordinated, how UPR components affect cancer cell biology and responsiveness to therapeutic interventions, and how UPR components/activities offer potentially novel targets for drug discovery, repurposing, and development. The volume will provide the most recent information on the signaling and regulation of the UPR, explore examples of how the UPR and/or specific components contribute to cancer biology, and identify and explore specific examples of potently new actionable targets for drug discovery and development from within the UPR and its regulation. Unique to the volume will be a specific focus on the UPR and its role in cancer biology, as well as a discussion of the role of the UPR in drug responses and resistance in cancer.
The Linc Complex
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Author : Gregg G. Gundersen
language : en
Publisher:
Release Date : 2018
The Linc Complex written by Gregg G. Gundersen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Cytoskeleton categories.
Aacr 2017 Proceedings Abstracts 1 3062
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Author : American Association for Cancer Research
language : en
Publisher: CTI Meeting Technology
Release Date : 2017-03-13
Aacr 2017 Proceedings Abstracts 1 3062 written by American Association for Cancer Research and has been published by CTI Meeting Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-13 with Medical categories.
The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.