Copper Catalyzed Electrophilic Amination Of Sp2 And Sp3 C H Bonds
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Copper Catalyzed Electrophilic Amination Of Sp2 And Sp3 C H Bonds
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Author : Stacey L. McDonald
language : en
Publisher: Springer
Release Date : 2016-08-18
Copper Catalyzed Electrophilic Amination Of Sp2 And Sp3 C H Bonds written by Stacey L. McDonald and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-18 with Science categories.
This thesis reports the latest developments in the direct amination of various C−H bonds using an H−Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines. The material outlined in this book shows how McDonald achieved C−H zincation using strong, non-nucleophilic zinc bases and subsequent electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines as the electrophilic nitrogen source. McDonald’s findings are of relevance to medicinal chemistry, drug discovery and materials science. Her thesis is a source of inspiration for scientists entering the field and students beginning their PhD in a related area.
Green Techniques For Organic Synthesis And Medicinal Chemistry
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Author : Wei Zhang
language : en
Publisher: John Wiley & Sons
Release Date : 2018-03-19
Green Techniques For Organic Synthesis And Medicinal Chemistry written by Wei Zhang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-19 with Science categories.
An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
Transition Metal Catalyzed Heterocycle Synthesis Via C H Activation
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Author : Xiao-Feng Wu
language : en
Publisher: John Wiley & Sons
Release Date : 2016-03-07
Transition Metal Catalyzed Heterocycle Synthesis Via C H Activation written by Xiao-Feng Wu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-07 with Technology & Engineering categories.
Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.
Advances In Organometallic Chemistry
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Author : Pedro J. Perez
language : en
Publisher: Academic Press
Release Date : 2020-03-17
Advances In Organometallic Chemistry written by Pedro J. Perez and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-17 with Science categories.
Advances in Organometallic Chemistry, Volume 73, the latest release in this longstanding serial, is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications. Specific chapters in this new release include Metal carbonyl promoted multicomponent coupling of alkyne for synthesis of heterocyclic compounds, Group 10 metal(0) complexes stabilized by phosphorus and carbon donor ligands, Synthesis of Nitrogen-containing Molecules via Transition Metal-Catalyzed Reactions on Isoxazoles, Anthraniils and Benzoisoxazoles, and more. Contains contributions from leading authorities in the field of organometallic chemistry Covers topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more Informs and updates readers on the latest developments in the field Carefully edited to provide easy-to-read material
Ruthenium In Catalysis
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Author : Pierre H. Dixneuf
language : en
Publisher: Springer
Release Date : 2014-10-18
Ruthenium In Catalysis written by Pierre H. Dixneuf and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-18 with Science categories.
The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics in pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors.
Oxidative Cross Coupling Reactions
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Author : Aiwen Lei
language : en
Publisher: John Wiley & Sons
Release Date : 2016-08-12
Oxidative Cross Coupling Reactions written by Aiwen Lei and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-12 with Technology & Engineering categories.
The first handbook on this emerging field provides a comprehensive overview of transition metal-catalyzed coupling reactions in the presence of an oxidant. Following an introduction to the general concept and mechanism of this reaction class, the team of authors presents chapters on C-C cross-coupling reactions using organometallic partners, C-Heteroatom bond forming reactions via oxidative couplings, and C-H couplings via C-H activation. The text also covers such groundbreaking topics as recent achievements in the fields of C-C and C-X bond formation reactions as well as C-H activation involving oxidative couplings. With its novel and concise approach towards important building blocks in organic chemistry and its focus on synthetic applications, this handbook is of great interest to all synthetic chemists in academia and industry alike.
Rhodium Catalysis
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Author : Carmen Claver
language : en
Publisher: Springer
Release Date : 2017-12-15
Rhodium Catalysis written by Carmen Claver and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-15 with Science categories.
The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published OnlineFirst with an individual DOI. In references, Topics in Organometallic Chemistry is abbrev iated as Top Organomet Chem and cited as a journal.
Fluorination
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Author : Jinbo Hu
language : en
Publisher: Springer
Release Date : 2020-08-12
Fluorination written by Jinbo Hu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-12 with Science categories.
This volume reviews the recent advances in formation of C-F bonds and X-F bonds (X = heteroatom) to produce useful fluorinated molecules for pharmaceuticals, materials and more. Reactions and methods associated with fluorination, including monofluorination, difluorination, trifluorination and other polyfluorination that have emerged within the past few years are systematically discussed. With contributions from front-line researchers in this field from both academia and industry, this book provides a valuable resource for scholars, graduate students as well as professionals.
Chiral Amine Synthesis
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Author : Thomas C. Nugent
language : en
Publisher: John Wiley & Sons
Release Date : 2010-01-14
Chiral Amine Synthesis written by Thomas C. Nugent and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-14 with Science categories.
This first comprehensive presentation of this hot and important topic compiles the most up-to-date methods for chiral amine synthesis. The international list of authors reads like a "Who's Who" of the subject, providing a large array of highly practical information concentrated into the useful and essential methods. Following an introductory chapter devoted to helping readers quickly determine which strategies to choose for their investigation, this handbook and ready reference focuses on the examination of methods that are reliable and simultaneously efficient for the synthesis of structurally diverse aliphatic and aromatic chiral amines. Modern methods and applications found in (pharmaceutical) industry are also covered.
Remote C H Bond Functionalizations
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Author : Debabrata Maiti
language : en
Publisher: John Wiley & Sons
Release Date : 2021-04-26
Remote C H Bond Functionalizations written by Debabrata Maiti and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-26 with Science categories.
A guide to contemporary advancements in the field of distal C-H functionalizations An important and dynamic topic within the modern field of organic synthesis, selective functionalization of C-H bonds can be used in a variety of applications across the pharmaceutical and agrochemical industries. Remote C-H Bond Functionalizations presents an inclusive account of the most recent developments and potential applications of performing variegated functionalizations selectively at the distal positions of organic compounds. Featuring contributions by an international team of experts, this authoritative volume provides deep insight into distal functionalizations, including detailed discussion of mechanisms, the engineering of templates, and the design of strategies. The text covers a diverse range of topics including C-H functionalization of palladium/norbornene catalysis, ruthenium-catalyzed remote functionalization, the non-directed distal C(sp2)-H, functionalization, transition metal catalyzed distal para-selective C-H functionalization, and much more. Reviewing contemporary advancements in the field while laying the foundation for future research, this important resource: Provides the most recent research and thorough coverage of the subject available in a single volume Offers practical information on C-H functionalizations in various industries Includes an up-to-date introduction to distal C-H functionalizations Remote C-H Bond Functionalizations is a must-read for every synthetic chemist, including chemists working with organometallics, organic chemists and researchers, and industrial chemists.