Crystallography Made Crystal Clear
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Crystallography Made Crystal Clear
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Author : Gale Rhodes
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Crystallography Made Crystal Clear written by Gale Rhodes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Crystallography Made Crystal Clear is designed to meet the need for an X-ray analysis that is between brief textbook sections and complete treatments. The book provides non-crystallographers with an intellectually satisfying explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts will foster wise use of the models, including the recognition of the strengths and weaknesses of pictures or computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells and carry out biologically important tasks, the book will be of interest to biologists. Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science background Leads the reader through clear, thorough, unintimidating explanations of the mathematics behind crystallography Explains how to read crystallography papers in research journals If you use computer-generated models of proteins or nucleic acids for: Studying molecular interactions Designing ligands, inhibitors, or drugs Engineering new protein functions Interpreting chemical, kinetic, thermodynamic, or spectroscopic data Studying protein folding Teaching macromolecule structure,and if you want to read new structure papers intelligently; become a wiser user of macromolecular models; and want to introduce undergraduates to the important subject of x-ray crystallography, then this book is for you.
Crystallography Made Crystal Clear
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Author : Gale Rhodes
language : en
Publisher: Turtleback Books
Release Date : 2006-02-01
Crystallography Made Crystal Clear written by Gale Rhodes and has been published by Turtleback Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-01 with Science categories.
Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs. * Helps readers to understand where models come from, so they don't use them blindly and inappropriately * Provides many visual and geometric models for understanding a largely mathematical method * Allows readers to judge whether recently published models are of sufficiently high quality and detail to be useful in their own work * Allows readers to study macromolecular structure independently and in an open-ended fashion on their own computers, without being limited to textbook or journals illustrations * Provides access to web tools ina format that will not go out of date. Links will be updated and added as existing resources change location or are added
Crystallography Made Crystal Clear
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Author : Arwen R. Pearson
language : en
Publisher: Academic Press
Release Date : 2022-01-15
Crystallography Made Crystal Clear written by Arwen R. Pearson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-15 with Science categories.
Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. It provides a comprehensive and concise reference for beginning macromolecular crystallographers and non-specialist users of crystallographic models. Visual and geometric models are used to help readers understand the physics and mathematics that form the basis of X-ray crystallography, and to understand both the extent but also limitations of the information that can be obtained in a diffraction experiment. Importantly, readers will learn how to use modern web-based tools to evaluate model and data quality. This updated and expanded new edition also includes discussion of the recent advances in infrastructure and automation and how these have impacted structural biology. Uses accessible language and updated graphics to explain complex topics Covers both traditional single crystal data collection as well as serial data collection and long-wavelength crystallography-the unique aspects of which are not currently covered in any other text Includes new chapters describing model building and model validation procedures with step-by-step guidance
Introduction To Crystallography
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Author : Frank Hoffmann
language : en
Publisher: Springer Nature
Release Date : 2020-07-31
Introduction To Crystallography written by Frank Hoffmann and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-31 with Science categories.
This book invites you on a systematic tour through the fascinating world of crystals and their symmetries. The reader will gain an understanding of the symmetry of external crystal forms (morphology) and become acquainted with all the symmetry elements needed to classify and describe crystal structures. The book explains the context in a very vivid, non-mathematical way and captivates with clear, high-quality illustrations. Online materials accompany the book; including 3D models the reader can explore on screen to aid in the spatial understanding of the structure of crystals. After reading the book, you will not only know what a space group is and how to read the International Tables for Crystallography, but will also be able to interpret crystallographic specifications in specialist publications. If questions remain, you also have the opportunity to ask the author on the book's website.
Pharmaceutical Crystallography
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Author : Andrew Bond
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-07-24
Pharmaceutical Crystallography written by Andrew Bond and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-24 with Medical categories.
The pharmaceutical industry has become acutely aware of the importance of the solid state, but pharmaceutical scientists often lack specific training in topics related to solid-state structure and crystallography. This book provides needed support in this topical area. Taking an intuitive and informal approach to solid-state structure and crystallographic concepts, this book is written for anyone who needs a clear understanding of modern crystallography, with specific reference to small-molecule pharmaceutical solids. The author describes molecular crystals and crystal structures, symmetry, space groups, single-crystal and powder X-ray diffraction techniques and the analysis and interpretation of crystallographic data. Useful technical details are presented where necessary and case studies from the pharmaceutical literature put theory into a practical context. Written by an internationally leading figure and with its focus on molecular crystals, this book is equally applicable to chemists with a need to understand and apply X-ray crystal-structure determination.
Protein Crystallography
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Author : Eaton E. Lattman
language : en
Publisher: JHU Press
Release Date : 2008-04-28
Protein Crystallography written by Eaton E. Lattman and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-28 with Science categories.
The proteome remains a mysterious realm. Researchers have determined the structures of only a small fraction of the proteins encoded by the human genome. Crystallography continues to be the primary method used to determine the structures of the remaining unknown proteins. This imaging technique uses the diffraction of X-rays to determine a protein’s three-dimensional molecular structure. Drawing on years of research and teaching experience, Eaton E. Lattman and Patrick J. Loll use clear examples and abundant illustrations to provide a concise and accessible primer on protein crystallography. Discussing the basics of diffraction, the behavior of two- and three-dimensional crystals, phase determination (including MIR and MAD phasing and molecular replacement), the Patterson function, and refinement, Lattman and Loll provide a complete overview of this important technique, illuminated by physical insights. The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.
Foundations Of Crystallography With Computer Applications
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Author : Maureen M. Julian
language : en
Publisher: CRC Press
Release Date : 2011-03-05
Foundations Of Crystallography With Computer Applications written by Maureen M. Julian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-05 with Science categories.
X-ray crystallography provides a unique opportunity to study the arrangement of atoms in a molecule. This book's modern computer-graphics centered approach facilitates the extrapolation of these valuable observations. A unified treatment of crystal systems, the book explains how atoms are arranged in crystals using the metric matrix. Featuring t
Crystallization Of Nucleic Acids And Proteins
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Author : Arnaud Ducruix
language : en
Publisher:
Release Date : 1999
Crystallization Of Nucleic Acids And Proteins written by Arnaud Ducruix and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Science categories.
Crystallography is the major method of determining structures of biological macromolecules yet crystallization techniques are still regarded as difficult to perform. This new edition of Crystallization of Nucleic Acids and Proteins: A Practical Approach continues in the vein of the first edition by providing a detailed and rational guide to producing crystals of proteins and nucleic acids of sufficient quantity and quality for diffraction studies. It has been thoroughly updated to include all the major new techniques such as the uses of molecular biology in structural biology (maximizing expression systems, sequence modifications to enable crystallization, and the introduction of anomalous scatterers); diagnostic analysis of prenucleation and nucleation by spectroscopic methods; and the two- dimensional electron crystallography of soluble proteins on planar lipid films. As well as an introduction to crystallogenesis, the other topics covered are: Handling macromolecular solutions, experimental design, seeding, proceeding from solutions to crystals Crystallization in gels Crystallization of nucleic acid complexes and membrane proteins Soaking techniques Preliminary characterization of crystals in order to tell whether they are suitable for diffraction studies. As with all Practical Approach books the protocols have been written by experienced researchers and are tried an tested methods. The underlying theory is brought together with the laboratory protocols to provide researchers with the conceptual and methodological tools necessary to exploit these powerful techniques. Crystallization of Nucleic Acids and Proteins: A Practical Approach 2e will be an invaluable manual of practical crystallization methods to researchers in molecular biology, crystallography, protein engineering, and biological chemistry.
Supercomputing Frontiers
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Author : David Abramson
language : en
Publisher: Springer
Release Date : 2019-06-07
Supercomputing Frontiers written by David Abramson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-07 with Computers categories.
This open access book constitutes the refereed proceedings of the 5th Asian Supercomputing Conference, SCFA 2019, held in Singapore in March 2019. The 6 full papers presented in this book were carefully reviewed and selected from 33 submissions. They cover a range of topics including memory fault handling, linear algebra, image processing, heterogeneous computing, resource usage prediction, and data caching.
Symmetry Relationships Between Crystal Structures
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Author : Ulrich Müller
language : en
Publisher: Oxford University Press
Release Date : 2013-04-04
Symmetry Relationships Between Crystal Structures written by Ulrich Müller and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-04 with Science categories.
The book presents the basic information needed to understand and to organize the huge amount of known structures of crystalline solids. Its basis is crystallographic group theory (space group theory), with special emphasis on the relations between the symmetry properties of crystals.