Deciphering New Molecular Mechanisms Of Mast Cell Activation
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Deciphering New Molecular Mechanisms Of Mast Cell Activation
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Author : Ulrich Blank
language : en
Publisher: Frontiers E-books
Release Date : 2014-03-20
Deciphering New Molecular Mechanisms Of Mast Cell Activation written by Ulrich Blank and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-20 with categories.
Mast cells are tissue-localized cells that play an important role in immunity and inflammation. Following an offensive event they act as cellular sensors that via the activation of cell surface receptors launch a cellular response culminating in the release of a whole set of inflammatory mediators and products. This response is initially destined to restore tissue homeostasis, but in case of chronic injury or deregulation also promotes pathology. To further understand the action of mast cells in their environmental context it is necessary to decipher the molecular mechanisms of their activation as well as the ensuing cellular responses. This will allow identification of new strategies to promote their beneficial actions or, at the contrary, to interfere with their pathological consequences. While in the past many studies have focused on responses engaged by high affinity IgE receptor because of its implication in the allergic response, it has become clear that mast cells can be activated by multiple types of receptors initiating an intense molecular crosstalk between receptors and signaling pathways that can either synergize, antagonize and in some cases produce new types of responses. Mast cells can indeed react with an astounding diverse array of cellular responses that sometimes are engaged selectively. This Research Topic will focus on selected articles that shed some new light on the molecular mechanisms of mast cell activation, the possible crosstalk between signaling pathways and the ensuing cellular responses that allow mast cells to act as cellular sensors in tissues.
Decipher Cellular And Molecular Mechanism Of The Development And Degeneration Of Functional Spinal Unit With Potential Therapeutic Approaches
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Author : Bo Gao
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-09
Decipher Cellular And Molecular Mechanism Of The Development And Degeneration Of Functional Spinal Unit With Potential Therapeutic Approaches written by Bo Gao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-09 with Science categories.
Nih Almanac
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Author : National Institutes of Health (U.S.). Division of Public Information
language : en
Publisher:
Release Date :
Nih Almanac written by National Institutes of Health (U.S.). Division of Public Information and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Federal aid to medical care research categories.
Understanding Cancer
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Author : David Tarin
language : en
Publisher: Springer Nature
Release Date : 2023-02-02
Understanding Cancer written by David Tarin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-02 with Medical categories.
This book provides a unique, wide-ranging description of the phenomenon of cancer and its pathological effects in diverse species including humans, domesticated and wild animals, invertebrates, and plants. The broad scope of information presented is used to construct radical new insights into biological self-regulation and explain their relevance to its disruption by cancerous growth and spread within the human body. Mechanisms of action of carcinogenic agents, initiation, progression, metastasis, inappropriate gene expression, dormancy, latency, regression, and reasons for susceptibility and/or resistance to cancer are all considered. Also discussed are criteria for pathological diagnosis, advances in treatment, implications for public health, and pitfalls in diagnosis and interpretation of experimental results. The book describes operational mechanisms of cancer at the levels of whole individual, organ, tissue, cell, molecular, and even atomic (quantum) scales of structural and physiological order. Evidence is assembled from all these levels of organization to show that cancer is a dynamically changing disorder and that it is an inherent and perpetual risk of multicellular composition. This provides pragmatic new biological and clinical perspectives on malignant neoplasia. The biological insight is that it is a consequence of progressing miscommunication within a cellular society. The clinical perspective is realistic but optimistic in reasoning that, although cancer can never be completely eradicated from human life, because it is a disorder of our intrinsic biological constitution, it can be controlled and ameliorated and even cured in a proportion of individuals. The text is profusely illustrated with over 300 macroscopic and microscopic pictures. It will stimulate curiosity and interest specialists, as well as beginners, in many scientific disciplines and provides copious references to the medical and scientific literature supporting its conclusions. Readers from fields as diverse as medicine, pathology, veterinary sciences, cell biology, molecular biology, developmental biology, and epidemiology will find the information the book contains thought-provoking, interesting, and useful. Additionally, specialists in occupational and environmental health and legal experts focusing on exposure to carcinogenic materials and pollution will find the contents valuable and informative.
Understanding Allergic Airway Diseases
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Author : Parteek Prasher
language : en
Publisher: Springer Nature
Release Date : 2024-06-25
Understanding Allergic Airway Diseases written by Parteek Prasher and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-25 with Medical categories.
The book explores the intersection of nanotechnology and allergic airway diseases. With a focus on diagnosis and management, each chapter delves into specific areas of interest. Beginning with an introduction to the diseases, the book progresses to uncover the pathophysiology and immunology underlying allergic airway diseases. The epidemiology chapter provides insights into the prevalence and impact of these conditions. A significant portion of the book is dedicated to nanotechnology applications, with chapters on metal and metal oxide nanoparticles, nanomicelles, carbon nanotubes, liposomes, polymeric nanoparticles, solid lipid nanoparticles, dendrimers, nanofibers, and quantum dots. These chapters delve into the potential of these nanomaterials in managing allergic airway diseases, highlighting their unique properties, and promising therapeutic approaches. Finally, the book concludes with a chapter on future directions, exploring emerging trends and potential advancements in the field. This book will be a valuable resource for academics, caregivers, researchers, and industry professionals working in the field of airway allergic diseases. It includes translational and clinical researchers, under-graduates and postgraduates (Masters), PhDs, and post-doctoral researchers of various disciplines, including pharmaceutical sciences, biotechnology, immunology, and medical and health sciences.
Comprehensive Treatise On Balanitis Understanding Managing And Thriving
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Author : Dr. Spineanu Eugenia
language : en
Publisher: Dr. Spineanu Eugenia
Release Date : 2024-11-25
Comprehensive Treatise On Balanitis Understanding Managing And Thriving written by Dr. Spineanu Eugenia and has been published by Dr. Spineanu Eugenia this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-25 with Medical categories.
The Essential Guide to Balanitis: An In-Depth Exploration COMPREHENSIVE OVERVIEW: Discover the origins, causes, and complexities of balanitis, from its history to modern medical advancements. DIAGNOSIS MADE CLEAR: Gain insights into diagnostic tests and procedures to identify and address this common condition accurately. EVIDENCE-BASED MANAGEMENT: Explore proven treatment strategies for both infectious and non-infectious balanitis tailored to individual needs. PREVENTION AND HYGIENE TIPS: Learn practical approaches to reduce risks, emphasizing hygiene and lifestyle modifications. HOLISTIC HEALTH PERSPECTIVE: Understand the interplay of anatomy, immunity, and personal habits in maintaining optimal genital health. This book is your ultimate resource for understanding balanitis, a condition often shrouded in stigma but crucial for male health. With a focus on clarity and actionable information, it empowers readers with knowledge about symptoms, risk factors, and treatments. Whether you're a healthcare provider, researcher, or an individual seeking insights, this guide offers a wealth of expertise to improve health and well-being. Take control of your knowledge and embrace a healthier approach to male genital health.
Immune Mechanisms In The Pathologic Response To Particles Fibers And Nanomaterials
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Author : Qiang Ma
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-11
Immune Mechanisms In The Pathologic Response To Particles Fibers And Nanomaterials written by Qiang Ma and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-11 with Medical categories.
Multi Omics Approaches For Decoding Heterogeneity In Cancer Immunotherapy
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Author : Lin Qi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-22
Multi Omics Approaches For Decoding Heterogeneity In Cancer Immunotherapy written by Lin Qi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-22 with Science categories.
Essentials Of Experimental Surgery
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Author : H Gregerson
language : en
Publisher: CRC Press
Release Date : 1996-05-28
Essentials Of Experimental Surgery written by H Gregerson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-05-28 with Medical categories.
This book covers all aspects of experimental gastrointestinal research including anatomy, physiology, surgical procedures and animal experimental models As well as being a useful reference guide to established scientists, it serves as an ideal introduction to the field of gastroenterology By consulting the book, the appropriate animal species and experimental model can be chosen for physiological and pathophysiological studies
Wintrobe S Clinical Hematology
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Author : Robert J. Means, Jr.
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2023-05-22
Wintrobe S Clinical Hematology written by Robert J. Means, Jr. and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-22 with Medical categories.
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.