Deciphering New Molecular Mechanisms Of Mast Cell Activation
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Deciphering New Molecular Mechanisms Of Mast Cell Activation
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Author : Ulrich Blank
language : en
Publisher: Frontiers E-books
Release Date : 2014-03-20
Deciphering New Molecular Mechanisms Of Mast Cell Activation written by Ulrich Blank and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-20 with categories.
Mast cells are tissue-localized cells that play an important role in immunity and inflammation. Following an offensive event they act as cellular sensors that via the activation of cell surface receptors launch a cellular response culminating in the release of a whole set of inflammatory mediators and products. This response is initially destined to restore tissue homeostasis, but in case of chronic injury or deregulation also promotes pathology. To further understand the action of mast cells in their environmental context it is necessary to decipher the molecular mechanisms of their activation as well as the ensuing cellular responses. This will allow identification of new strategies to promote their beneficial actions or, at the contrary, to interfere with their pathological consequences. While in the past many studies have focused on responses engaged by high affinity IgE receptor because of its implication in the allergic response, it has become clear that mast cells can be activated by multiple types of receptors initiating an intense molecular crosstalk between receptors and signaling pathways that can either synergize, antagonize and in some cases produce new types of responses. Mast cells can indeed react with an astounding diverse array of cellular responses that sometimes are engaged selectively. This Research Topic will focus on selected articles that shed some new light on the molecular mechanisms of mast cell activation, the possible crosstalk between signaling pathways and the ensuing cellular responses that allow mast cells to act as cellular sensors in tissues.
Mast Cell Biology
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Author : Alasdair M. Gilfillan
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28
Mast Cell Biology written by Alasdair M. Gilfillan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
Decipher Cellular And Molecular Mechanism Of The Development And Degeneration Of Functional Spinal Unit With Potential Therapeutic Approaches
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Author : Bo Gao
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-09
Decipher Cellular And Molecular Mechanism Of The Development And Degeneration Of Functional Spinal Unit With Potential Therapeutic Approaches written by Bo Gao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-09 with Science categories.
Understanding Molecular Mechanisms In Diabetic Cardiomyopathy Dcm
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Author : VijayaKumar Sukumaran
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-03
Understanding Molecular Mechanisms In Diabetic Cardiomyopathy Dcm written by VijayaKumar Sukumaran and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-03 with Medical categories.
Indoor Allergens
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1993-02-01
Indoor Allergens written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-02-01 with Science categories.
More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other allergic diseases. Many of these conditions are caused by exposure to allergens in indoor environments such as the house, work, and schoolâ€"where we spend as much as 98 percent of our time. Developed by medical, public health, and engineering professionals working together, this unique volume summarizes what is known about indoor allergens, how they affect human health, the magnitude of their effect on various populations, and how they can be controlled. The book addresses controversies, recommends research directions, and suggests how to assist and educate allergy patients, as well as professionals. Indoor Allergens presents a wealth of information about common indoor allergens and their varying effects, from significant hay fever to life-threatening asthma. The volume discusses sources of allergens, from fungi and dust mites to allergenic chemicals, plants, and animals, and examines practical measures for their control. Indoor Allergens discusses how the human airway and immune system respond to inhaled allergens and assesses patient testing methods, covering the importance of the patient's medical history and outlining procedures and approaches to interpretation for skin tests, in vitro diagnostic tests, and tests of patients' pulmonary function. This comprehensive and practical volume will be important to allergists and other health care providers; public health professionals; specialists in building design, construction, and maintenance; faculty and students in public health; and interested allergy patients.
Clinical Immunology E Book
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Author : Robert R. Rich
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-01-13
Clinical Immunology E Book written by Robert R. Rich and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-13 with Medical categories.
Keep abreast of the latest advances in this complex field with the 5th Edition of Clinical Immunology: Principles and Practice. This substantially revised edition by Drs. Robert R. Rich, Thomas A. Fleisher, William T. Shearer, Harry W. Schroeder, Jr., Anthony J. Frew, and Cornelia M. Weyand, offers authoritative guidance from some of the most respected global leaders in immunology, helping you navigate today’s latest knowledge and evidence-based practices that result in improved patient care. This trusted resource features sweeping content updates, rewritten chapters, a highly clinical perspective, and an easy-to-use organization designed to enhance your diagnosis and management skills in daily practice. Includes new chapters on the Microbiota in Immunity and Inflammation, Immune Responses to Fungi, and Genetics and Genomics of Immune Response. Features extensive revisions to many chapters, including the Major Histocompatibility Complex, Multiple Sclerosis, Diabetes and Related Autoimmune Diseases, Biologic Modifiers of Inflammation and Tumor Immunotherapy. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Summarizes promising research and development anticipated over the next 5-10 years with "On the Horizon" boxes and discussion of translational research.
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 1986
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Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
language : en
Publisher:
Release Date : 1985
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 1986 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with United States categories.
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 1987
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Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
language : en
Publisher:
Release Date : 1986
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 1987 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with United States categories.
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 1987 Department Of Labor Pt 2 Department Of Health And Human Services
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Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
language : en
Publisher:
Release Date : 1986
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 1987 Department Of Labor Pt 2 Department Of Health And Human Services written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with United States categories.
Molecular And Multi Omic Approaches In Understanding Cancer Biology And Anticancer Therapies Current Perspectives And New Challenges
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Author : Basel A. Abdel-Wahab
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-03
Molecular And Multi Omic Approaches In Understanding Cancer Biology And Anticancer Therapies Current Perspectives And New Challenges written by Basel A. Abdel-Wahab and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-03 with Science categories.