Multi Omics Approaches For Decoding Heterogeneity In Cancer Immunotherapy
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Multi Omics Approaches For Decoding Heterogeneity In Cancer Immunotherapy
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Author : Lin Qi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-22
Multi Omics Approaches For Decoding Heterogeneity In Cancer Immunotherapy written by Lin Qi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-22 with Science categories.
Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy
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Author : Attila Szöllősi
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-19
Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy written by Attila Szöllősi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-19 with Medical categories.
Based on statistical data provided by the World Health Organization, cancer is widely acknowledged as the foremost contributor to global mortality and persists as a significant concern in the contemporary era. In recent times, immunotherapy has been demonstrated as an efficacious approach in diverse advanced solid tumors, especially in thoracic tumors, consequently emerging as a prominent area of focus in the investigation of antitumor pharmaceuticals. The utilization of immunotherapy directed towards programmed death ligand-1 (PD-L1) and programmed cell death protein-1 (PD-1) has emerged as a valid approach, resulting in substantial enhancements in both disease-free and overall survival rates among cancer patients. Moreover, applications of multi-omics analyses in thoracic tumors have made great progress. However, it also ushered in new challenges. Certain subtypes of thoracic cancer have been identified as immune-quiescent tumors, indicating that only a limited number of patients would derive benefits from immunotherapy while also experiencing a high incidence of severe adverse events. Besides, multi-omics analyses reveal patterns of drug resistance and relapse in the treatment of thoracic tumors, which help us identify the molecular mechanisms that lead to drug resistance and provide clues for overcoming it. Meanwhile, exploring the role of the tumor microenvironment (TME) in the development and metastasis of thoracic tumors can help us better understand the potential mechanisms of tumor spread and find approaches to intervene.
Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer
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Author : Hongda Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-24
Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer written by Hongda Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-24 with Medical categories.
According to the most recent projections of the International Agency for Research on Cancer (IARC), there would be around 19.3 million new cases of cancer and 10 million cancer-related deaths globally in 2022. Cancer research has never halted. In particular, research into the cancer immunological microenvironment is gaining popularity.
Multi Omics Analysis In Tumor Microenvironment And Tumor Heterogeneity
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Author : Jinhui Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-25
Multi Omics Analysis In Tumor Microenvironment And Tumor Heterogeneity written by Jinhui Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-25 with Science categories.
Omics Approaches And Technologies In Covid 19
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Author : Debmalya Barh
language : en
Publisher: Academic Press
Release Date : 2022-12-01
Omics Approaches And Technologies In Covid 19 written by Debmalya Barh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-01 with Medical categories.
The COVID-19 pandemic has affected the entire world in an unprecedented way since 2019. However, novel and innovative applications of various omics, computational, and smart technologies have helped manage the pandemic of the 21st century in a very effective manner. Omics approaches and technologies in COVID-19 presents up-to-date knowledge on omics, genetic engineering, mathematical and computational approaches, and advanced technologies in the diagnosis, prevention, monitoring, and management of COVID-19. This book contains 26 chapters written by academic and industry experts from more than 15 countries. Split into three sections (Omics; Artificial Intelligence and Bioinformatics; and Smart and Emerging Technologies), it brings an overview of novel technologies under omics such as, genomic, metagenomic, pangenomic, metabolomics and proteomics in COVID-19. In addition, it discusses hostpathogen interactions and interactomics, management options, application of genetic engineering, mathematical modeling andsimulations, systems biology, and bioinformatics approaches in COVID-19 drug discovery and vaccine development. This is a valuable resource for students, biotechnologists, bioinformaticians, virologists, clinicians, and pharmaceutical, biomedical, and healthcare industry people who want to understand the promising omics and other technologies used in combating COVID-19 from various aspects. - Provides novel technologies for rapid diagnostics, drug discovery, vaccine development, monitoring, prediction of future waves, etc. - Describes various omics applications including genomics, metagenomics, epigenomics, nutrigenomics, transcriptomics,miRNAomics, proteomics, metabolomics, phenomics, multiomics, etc., in COVID-19 - Presents applications of genetic engineering, CRISPR, artificial intelligence, mathematical and in silico modeling, systems biology,and other computational approaches in COVID-19 - Discusses emerging, digital, and smart technologies for the monitoring and management of COVID-19
Immunological Precision Therapeutics Integrating Multi Omics Technologies And Comprehensive Approaches For Personalized Immune Intervention
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Author : Wenyi Jin
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-20
Immunological Precision Therapeutics Integrating Multi Omics Technologies And Comprehensive Approaches For Personalized Immune Intervention written by Wenyi Jin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-20 with Medical categories.
In the realm of modern immunology, the pursuit of precision therapeutics has emerged as a paramount endeavor. This research field harnesses the power of advanced multi-omics technologies and comprehensive methodologies to revolutionize personalized immune interventions. Immunotherapy, a cornerstone of precision medicine, targets the intricate dynamics of the immune system to combat diseases ranging from cancer to autoimmune disorders. Integrating multi-omics analyses, including genomics, transcriptomics, proteomics, and metabolomics, enables a holistic understanding of immune responses at various molecular levels. Immune signatures derived from these analyses unveil individualized patterns, offering crucial insights into disease susceptibility and treatment efficacy. Leveraging this wealth of data through sophisticated computational models and machine learning algorithms enhances our ability to predict immune responses and identify optimal therapeutic strategies. By amalgamating diverse approaches, from single-cell profiling to spatial transcriptomics, we delve deeper into the complexities of immune regulation and cellular interactions within the microenvironment. Through collaborative efforts, the pursuit of immunological precision therapeutics aims to tailor interventions precisely to each patient's immune landscape, ushering in a new era of personalized immune modulation.
Combinatorial Approaches For Cancer Treatment From Basic To Translational Research
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Author : Daniela Spano
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-03
Combinatorial Approaches For Cancer Treatment From Basic To Translational Research written by Daniela Spano and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-03 with Science categories.
Characterizing The Multi Faceted Dynamics Of Tumor Cell Plasticity
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Author : Satyendra Chandra Tripathi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-01
Characterizing The Multi Faceted Dynamics Of Tumor Cell Plasticity written by Satyendra Chandra Tripathi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-01 with Science categories.
Single Cell Omics
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Author : Debmalya Barh
language : en
Publisher: Academic Press
Release Date : 2019-06-06
Single Cell Omics written by Debmalya Barh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-06 with Medical categories.
Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis. - Covers not only the technological aspects, but also the diverse applications of single cell omics in the biomedical field - Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis - Written by experts across the world, bringing different points-of-view and case studies to give a comprehensive overview on the topic
Single Cell Molecular Characterization For Improving Cancer Immunotherapy
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Author : Qihui Shi
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-22
Single Cell Molecular Characterization For Improving Cancer Immunotherapy written by Qihui Shi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-22 with Medical categories.
Topic Editor Qihui Shi is the scientific co-founder of JunHealth, a company aiming to developing single-cell sequencing technologies for clinical applications, and received research funding from BeiGene.