Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer
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Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer
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Author : Hongda Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-24
Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer written by Hongda Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-24 with Medical categories.
According to the most recent projections of the International Agency for Research on Cancer (IARC), there would be around 19.3 million new cases of cancer and 10 million cancer-related deaths globally in 2022. Cancer research has never halted. In particular, research into the cancer immunological microenvironment is gaining popularity.
Identification Of Biomarkers For Cancer Immunotherapy From Bench To Bedside Volume I
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Author : Chang Gu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-20
Identification Of Biomarkers For Cancer Immunotherapy From Bench To Bedside Volume I written by Chang Gu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-20 with Science categories.
During the past few decades, immunotherapy has become an established pillar of cancer treatment improving the survival of numerous patients with diverse solid and hematologic tumors. The leading causes behind the success are the discovery of immune checkpoint inhibitors (ICIs) and the development of chimeric antigen receptor (CAR) T/M/NK cells. As for ICIs, malignancies take advantage of the inhibitory programmed cell death protein 1/programmed cell death protein ligand 1 (PD-1/PD-L1) or cytotoxic T-lymphocyte-associated protein (CTLA-4) pathways to evade the immune system, and disruption of the axis by immune checkpoint inhibitors can achieve durable disease remissions, which has been proved by basic researches and (pre-) clinical studies among lung cancer, melanoma, renal cell cancer, head, and neck squamous cell carcinoma, urothelial cancer, and Hodgkin’s disease. However, the 5-year survival rate of patients treated with ICIs varies with each individual and also relies on tumor specific pathological or molecular subtypes. Besides, the efficacy of ICIs is still limited in terms of drug resistance and fewer potential responders. Thus, there is a big challenge to identify and develop more novel reliable ICIs, as well as sensibilize existing ICIs for patients with drug resistance or even for non-responders.
Exploring The Breast Tumor Microenvironment Association To Metastasis Novel Risk Factors And Novel Treatments And Immunotherapies
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Author : Jorge Morales-Montor
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-10
Exploring The Breast Tumor Microenvironment Association To Metastasis Novel Risk Factors And Novel Treatments And Immunotherapies written by Jorge Morales-Montor and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-10 with Medical categories.
Insights In Cancer Genetics And Oncogenomics 2022
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Author : Anton A. Buzdin
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-27
Insights In Cancer Genetics And Oncogenomics 2022 written by Anton A. Buzdin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-27 with Science categories.
Identification Of Multi Biomarker For Cancer Diagnosis And Prognosis Based On Network Model And Multi Omics Data
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Author : Chunquan Li
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-02
Identification Of Multi Biomarker For Cancer Diagnosis And Prognosis Based On Network Model And Multi Omics Data written by Chunquan Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-02 with Science categories.
Deep Learning For Cancer Diagnosis
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Author : Utku Kose
language : en
Publisher: Springer Nature
Release Date : 2020-09-12
Deep Learning For Cancer Diagnosis written by Utku Kose and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-12 with Technology & Engineering categories.
This book explores various applications of deep learning to the diagnosis of cancer,while also outlining the future face of deep learning-assisted cancer diagnostics. As is commonly known, artificial intelligence has paved the way for countless new solutions in the field of medicine. In this context, deep learning is a recent and remarkable sub-field, which can effectively cope with huge amounts of data and deliver more accurate results. As a vital research area, medical diagnosis is among those in which deep learning-oriented solutions are often employed. Accordingly, the objective of this book is to highlight recent advanced applications of deep learning for diagnosing different types of cancer. The target audience includes scientists, experts, MSc and PhD students, postdocs, and anyone interested in the subjects discussed. The book can be used as a reference work to support courses on artificial intelligence, medical and biomedicaleducation.
Immunotherapy Of Hepatocellular Carcinoma
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Author : Tim F. Greten
language : en
Publisher: Springer
Release Date : 2018-08-22
Immunotherapy Of Hepatocellular Carcinoma written by Tim F. Greten and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-22 with Medical categories.
In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.
Computational Methods For Single Cell Data Analysis
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Author : Guo-Cheng Yuan
language : en
Publisher: Humana Press
Release Date : 2019-02-14
Computational Methods For Single Cell Data Analysis written by Guo-Cheng Yuan and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-14 with Science categories.
This detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-type identification, and spatial transcriptomics analysis, all with a focus on hands-on implementation of computational methods for analyzing experimental data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Methods for Single-Cell Data Analysis aims to cover a wide range of tasks and serves as a vital handbook for single-cell data analysis.
Histopathology
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Author : Supriya Srivastava
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-09-19
Histopathology written by Supriya Srivastava and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-19 with Medical categories.
This book, "Histopathology-An Update" is a comprehensive book that deals with the latest advances in the field of histopathology. This book will be of help to pathologists, clinicians and researchers in the latest update in histopathology of various organs.
Oral Cancer
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Author : Gokul Sridharan
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-01-07
Oral Cancer written by Gokul Sridharan and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-07 with Medical categories.
Oral cancer is a common disease with a high incidence of morbidity and mortality. Despite technological advancements in diagnosis and treatment, the five-year survival rate is low. Researchers worldwide are attempting to identify new and novel methods for early diagnosis and better treatment of oral cancer to improve survival rate and quality of life post recovery. This book examines current concepts in oral cancer and emphasizes future perspectives for diagnosis and treatment of disease for better clinical outcomes and patient care.