Multi Omics Analysis In Tumor Microenvironment And Tumor Heterogeneity
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Multi Omics Analysis In Tumor Microenvironment And Tumor Heterogeneity
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Author : Jinhui Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-25
Multi Omics Analysis In Tumor Microenvironment And Tumor Heterogeneity written by Jinhui Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-25 with Science categories.
Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy
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Author : Attila Szöllősi
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-19
Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy written by Attila Szöllősi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-19 with Medical categories.
Based on statistical data provided by the World Health Organization, cancer is widely acknowledged as the foremost contributor to global mortality and persists as a significant concern in the contemporary era. In recent times, immunotherapy has been demonstrated as an efficacious approach in diverse advanced solid tumors, especially in thoracic tumors, consequently emerging as a prominent area of focus in the investigation of antitumor pharmaceuticals. The utilization of immunotherapy directed towards programmed death ligand-1 (PD-L1) and programmed cell death protein-1 (PD-1) has emerged as a valid approach, resulting in substantial enhancements in both disease-free and overall survival rates among cancer patients. Moreover, applications of multi-omics analyses in thoracic tumors have made great progress. However, it also ushered in new challenges. Certain subtypes of thoracic cancer have been identified as immune-quiescent tumors, indicating that only a limited number of patients would derive benefits from immunotherapy while also experiencing a high incidence of severe adverse events. Besides, multi-omics analyses reveal patterns of drug resistance and relapse in the treatment of thoracic tumors, which help us identify the molecular mechanisms that lead to drug resistance and provide clues for overcoming it. Meanwhile, exploring the role of the tumor microenvironment (TME) in the development and metastasis of thoracic tumors can help us better understand the potential mechanisms of tumor spread and find approaches to intervene.
Computational Methods For Multi Omics Data Analysis In Cancer Precision Medicine
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Author : Ehsan Nazemalhosseini-Mojarad
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-02
Computational Methods For Multi Omics Data Analysis In Cancer Precision Medicine written by Ehsan Nazemalhosseini-Mojarad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-02 with Science categories.
Cancer is a complex and heterogeneous disease often caused by different alterations. The development of human cancer is due to the accumulation of genetic and epigenetic modifications that could affect the structure and function of the genome. High-throughput methods (e.g., microarray and next-generation sequencing) can investigate a tumor at multiple levels: i) DNA with genome-wide association studies (GWAS), ii) epigenetic modifications such as DNA methylation, histone changes and microRNAs (miRNAs) iii) mRNA. The availability of public datasets from different multi-omics data has been growing rapidly and could facilitate better knowledge of the biological processes of cancer. Computational approaches are essential for the analysis of big data and the identification of potential biomarkers for early and differential diagnosis, and prognosis.
Multi Omics Approaches For Decoding Heterogeneity In Cancer Immunotherapy
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Author : Lin Qi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-22
Multi Omics Approaches For Decoding Heterogeneity In Cancer Immunotherapy written by Lin Qi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-22 with Science categories.
Multi Omic Data Integration In Oncology
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Author : Chiara Romualdi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-03
Multi Omic Data Integration In Oncology written by Chiara Romualdi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-03 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Molecular And Multi Omic Approaches In Understanding Cancer Biology And Anticancer Therapies Current Perspectives And New Challenges
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Author : Basel A. Abdel-Wahab
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-03
Molecular And Multi Omic Approaches In Understanding Cancer Biology And Anticancer Therapies Current Perspectives And New Challenges written by Basel A. Abdel-Wahab and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-03 with Science categories.
Integrative Analysis Of Single Cell And Or Bulk Multi Omics Sequencing Data
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Author : Geng Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-13
Integrative Analysis Of Single Cell And Or Bulk Multi Omics Sequencing Data written by Geng Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-13 with Science categories.
Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer
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Author : Hongda Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-24
Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer written by Hongda Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-24 with Medical categories.
According to the most recent projections of the International Agency for Research on Cancer (IARC), there would be around 19.3 million new cases of cancer and 10 million cancer-related deaths globally in 2022. Cancer research has never halted. In particular, research into the cancer immunological microenvironment is gaining popularity.
Advances In Methods And Tools For Multi Omics Data Analysis
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Author : Ornella Cominetti
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-12
Advances In Methods And Tools For Multi Omics Data Analysis written by Ornella Cominetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-12 with Science categories.
Metabolism Meets Function The Multifaced Role Of Metabolism In Cancer
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Author : Andrea Morandi
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-27
Metabolism Meets Function The Multifaced Role Of Metabolism In Cancer written by Andrea Morandi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-27 with Medical categories.