Immune Mechanisms In The Pathologic Response To Particles Fibers And Nanomaterials
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Immune Mechanisms In The Pathologic Response To Particles Fibers And Nanomaterials
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Author : Qiang Ma
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-11
Immune Mechanisms In The Pathologic Response To Particles Fibers And Nanomaterials written by Qiang Ma and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-11 with Medical categories.
Interaction Of Nanomaterials With The Immune System
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Author : James C. Bonner
language : en
Publisher: Springer Nature
Release Date : 2020-01-30
Interaction Of Nanomaterials With The Immune System written by James C. Bonner and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-30 with Medical categories.
This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs.
Unraveling The Safety Profile Of Nanoscale Particles And Materials
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Author : Andreia Ferreira de Castro Gomes
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-03-21
Unraveling The Safety Profile Of Nanoscale Particles And Materials written by Andreia Ferreira de Castro Gomes and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Technology & Engineering categories.
As nanomaterials become increasingly present in our daily lives, pertinent questions regarding their safety arise. Nanomaterial risk assessment, as in other areas, directs much of the effort worldwide in defining guidelines that may be translated into national or international directives. Nanomaterials encompass different entities, from nanoparticles to nanostructured materials, with specific effects over cells, tissues, organisms and ecosystems depending on their biophysical characteristics. Such interactions will directly affect the impact of novel nanotechnologies. This book aims to provide the reader with a comprehensive overview of the current state of the art in nanotoxicology, featuring the most important developments and critical issues regarding the use of and exposure to nanoparticles.
Human Immune System
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Author : Shyamasree Ghosh
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2022-02-21
Human Immune System written by Shyamasree Ghosh and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-21 with Science categories.
The fast development in the field of nanotechnology has led to a high variety of nanoparticles. Nanoparticles find importance in every sphere of human lives and more so in the recent years have tremendous applications in the sector of biomedical clinical medicine as diagnostic, prognostic and imaging tools. Their risk to human and animal life as well as to the environment is still unclear. Therefore, the study of the impact of nanoparticles on human and animal life is important. Volume I highlights the impact of nanoparticles on the human immune system. While discussing the basic biology of the immune system, this book highlights the downstream effect of nanoparticles on the human immune system. Research studies on the development of better and more effective nanoparticles with more precise and accurate effects and with toxic minimal side effects are discussed in the book. Both volumes are also included in a set ISBN 978-3-11-065666-4.
Reactive Oxygen Species Ros Nanoparticles And Endoplasmic Reticulum Er Stress Induced Cell Death Mechanisms
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Author : Loutfy H. Madkour
language : en
Publisher: Academic Press
Release Date : 2020-06-27
Reactive Oxygen Species Ros Nanoparticles And Endoplasmic Reticulum Er Stress Induced Cell Death Mechanisms written by Loutfy H. Madkour and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-27 with Medical categories.
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment
Biochemical Toxicology
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Author : Muharrem Ince
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-07-29
Biochemical Toxicology written by Muharrem Ince and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-29 with Medical categories.
Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.
Nanoparticles And The Immune System
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Author : Diana Boraschi
language : en
Publisher: Academic Press
Release Date : 2013-11-29
Nanoparticles And The Immune System written by Diana Boraschi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-29 with Medical categories.
Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage for amplifying immune responses in certain diseases or preventive strategies (e.g. vaccination). Identifies endpoints relevant for assessing hazardous situations, evaluating the impact on immunologically frail populations and how to gauge chronic/cumulative effects Raises the awareness of the importance of knowing the effects of the new nanomaterials on our immune system
Interaction Of Nanomaterials With The Immune System Role In Nanosafety And Nanomedicine
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Author : Paola Italiani
language : en
Publisher: Frontiers Media SA
Release Date : 2018-04-10
Interaction Of Nanomaterials With The Immune System Role In Nanosafety And Nanomedicine written by Paola Italiani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-10 with categories.
The immune system has the double role of maintaining tissue integrity and homeostasis and of protecting the organism from possible dangers, from invading pathogens to environmentally-borne dangerous chemicals. New chemicals recognisable by the immune system are engineered nanomaterials/ nanoparticles, new agents in our environment that are becoming common due to their presence in many products, from constructions and building material (e.g., solar cells, pigments and paints, tilesand masonry materials) to daily products (e.g., food packaging, cosmetics, and cigarettes). Human beings can be accidentally exposed to engineered nanomaterials when these are released from products containing them or during production in workplaces. Furthermore, intentional exposure occurs in medicine, as engineered nanoparticles are used as tools for improving delivery of drugs and vaccines, vaccine adjuvants and contrast agents in therapeutic, preventive and diagnostic strategies. Nanoparticles that come in contact with the immune system after unintentional exposure need to be eliminated from the organism as they represent a potential threat. In this case, however, due to their peculiar characteristics of size, shape, surface charge and persistence, nanoparticles may elicit undesirable reactions and have detrimental effects on the immune system, such as cytotoxicity, inflammation, anaphylaxis, immunosuppression. Conversely, nanomedicines need to escape immune recognition/elimination and must persist in the organism long enough for reaching their target and exerting their beneficial effects. Immune cells and molecules at the body surface (airway and digestive mucosae, skin) are the first that come in contact with nanomaterials upon accidental exposure, while immune effectors in blood are those that more easily come in contact with nanomedical products. Thus, evaluating the interaction of the immune system with nanoparticles/nanomaterials is a topic of key importance both in nanotoxicology and in nanomedicine. Immuno-nanosafety studies consider both accidental exposure to nanoparticles, which may occur by skin contact, ingestion or inhalation (at doses and with a frequency that are not known), and medical exposure, which takes place with a defined administration schedule (route, dose, frequency). Many studies focus on the interaction between the immune system and nanoparticles that, for medical purposes, have been specifically modified to stimulate immunity or to avoid immune recognition, as in the case of vaccine carriers/adjuvants or drug delivery systems, respectively. The aims of this Research Topic is to provide an overview of recent strategies: 1.for assessing the immunosafety of engineered nanomaterials/nanoparticles, in particular in terms of activation of inflammatory responses, such as complement activation and allergic reactions, based on the nanomaterial intrinsic characteristics and on the possible carry-over of bioactive contaminants such as LPS. Production of new nanoparticles taking into account their effects on immune responses, in order to avoid undesirable effects on one hand, and to design particles with desirable effects for medical applications on the other hand; 2.for designing more effective nanomedicines by either avoiding or exploiting their interaction with the immune systems, with particular focus on cancer diagnosis and therapy, and vaccination. This collection of articles gives a comprehensive view of the state-of-the-art of the interaction of nanoparticles with the immune system from the two perspectives of safety and medical use, and aims at providing immunologists with the relevant knowledge for designing improved strategies for immunologically safe nanomaterial applications.
Phagocytes In Immunity Linking Material Internalization To Immune Responses And Therapeutic Strategies
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Author : Johnathan Canton
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-12
Phagocytes In Immunity Linking Material Internalization To Immune Responses And Therapeutic Strategies written by Johnathan Canton and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-12 with Medical categories.
Green Synthesis Characterization And Applications Of Nanoparticles
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Author : Ashutosh Kumar Shukla
language : en
Publisher: Elsevier
Release Date : 2018-11-26
Green Synthesis Characterization And Applications Of Nanoparticles written by Ashutosh Kumar Shukla and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-26 with Technology & Engineering categories.
Green Synthesis, Characterization and Applications of Nanoparticles shows how eco-friendly nanoparticles are engineered and used. In particular, metal nanoparticles, metal oxide nanoparticles and other categories of nanoparticles are discussed. The book outlines a range of methodologies and explores the appropriate use of each. Characterization methods include spectroscopic, microscopic and diffraction methods, but magnetic resonance methods are also included as they can be used to understand the mechanism of nanoparticle synthesis using organisms. Applications covered include targeted drug delivery, water purification and hydrogen generation. This is an important research resource for those wishing to learn more about how eco-efficient nanoparticles can best be used. Theoretical details and mathematical derivations are kept to a necessary minimum to suit the need of interdisciplinary audiences and those who may be relatively new to the field. Explores recent trends in growth, characterization, properties and applications of nanoparticles Gives readers an understanding on how they are applied through the use of case studies and examples Assesses the advantages and disadvantages of a variety of synthesis and characterization techniques for green nanoparticles in different situations