Design And Development Of New Therapeutics Against Infectious Diseases Using Computational And Experimental Approaches
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Design And Development Of New Therapeutics Against Infectious Diseases Using Computational And Experimental Approaches
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Author : Parth Sarthi Sen Gupta
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-15
Design And Development Of New Therapeutics Against Infectious Diseases Using Computational And Experimental Approaches written by Parth Sarthi Sen Gupta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-15 with Science categories.
Infectious diseases are caused by bacteria, fungus, viruses, and other microorganisms. Biomolecules such as proteins, DNA, and/or RNA play a crucial role in the infections of these disorders. These infectious illnesses are often transmissible, meaning they may be passed from one person to another by a variety of means. Even though medical technology has progressed, some illnesses continue to cause anxiety among individuals worldwide. If we examine the situation of COVID-19, the entire world is terrified of the pandemic. Similarly, In the last decades, other infections including Dengue, Chikungunya, Zika, Ebola, Japanese Encephalitis Virus (JEV), influenza, the common cold, tuberculosis (TB), Hepatitis A and B and human immunodeficiency syndrome (HIV) have also challenged the human population.
Multidisciplinary Research In Arts Science Commerce Volume 19
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Author : Chief Editor- Biplab Auddya, Editor- Abhishek Bajaj, Dr. Jay Prakash Rajak, Dr. Srilatha.Y, Megha Thankachan, Dr. Vidya G, Dr. Santanu Bhattacharya
language : en
Publisher: The Hill Publication
Release Date : 2025-01-24
Multidisciplinary Research In Arts Science Commerce Volume 19 written by Chief Editor- Biplab Auddya, Editor- Abhishek Bajaj, Dr. Jay Prakash Rajak, Dr. Srilatha.Y, Megha Thankachan, Dr. Vidya G, Dr. Santanu Bhattacharya and has been published by The Hill Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-24 with Antiques & Collectibles categories.
Structure Based Drug Design
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Author : Marcelo A. Marti
language : en
Publisher: Springer Nature
Release Date : 2024-10-15
Structure Based Drug Design written by Marcelo A. Marti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-15 with Medical categories.
This volume focuses on target-oriented approximations to drug discovery, including target selection, binding pocket detection, and current uses and variants of molecular dynamics and molecular docking. The primary audience is PhD and graduates working in the field of molecular biology, structural biology, pharmaceutical sciences.
Small Molecules And Peptide Based Candidates As Therapeutics And Vaccines For Covid 19 Pandemic
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Author : Da’san Mahmoud Mousa Jaradat
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-16
Small Molecules And Peptide Based Candidates As Therapeutics And Vaccines For Covid 19 Pandemic written by Da’san Mahmoud Mousa Jaradat and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Science categories.
Topic Editor Dr. Balakumar Chandrasekaran holds patents relating to N-substituted isatin hydrazones as antimycobacterial and antimicrobial agents, and Pharmaceutical Compounds. Topic Editor Dr. Munir Al-Zeer holds a patent relating to Method for the Preparation of an Influenza Virus. All other Topic Editors declare no competing interests.
Bioinformatics Of Human Proteomics
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Author : Xiangdong Wang
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-01-26
Bioinformatics Of Human Proteomics written by Xiangdong Wang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-26 with Science categories.
“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.
Translational Bioinformatics
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-03-06
Translational Bioinformatics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-06 with Science categories.
Translational Bioinformatics is an emerging field in the direction of biomedical research. High throughput technologies can be applied to the generated biological data to develop the vaccine and personalized medicine. This volume consists of the chapters from different stalwart of the field covering the topics such as drug development, vector engineering, vaccine development and translational genomics. Chapters covered in this volume discuss the translational research related with cancer, Alzheimer disease and cardiovascular diseases. This volume includes the chapter describing the importance of computational resources and chemoinformatics for the translational health research. How Omics studies are helping to translate the laboratory data into the development of tools which are beneficial in the clinics have been described. How translational bioinformatics helpful in plant genomics to improve the crops have also been included in this volume. This volume has a chapter which describes the secrets of resistance development and further how these resistance are associated with human infectious diseases. This volume will be useful to the early career researcher in the development of research idea and develop their methodologies in the direction of bioinformatics and it will also give the insight to translate their findings. - Translational Bioinformatics - Health Informatics - Multi-omics
Current Trends In The Identification And Development Of Antimicrobial Agents
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Author : M. Amin-ul Mannan
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-03-08
Current Trends In The Identification And Development Of Antimicrobial Agents written by M. Amin-ul Mannan and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-08 with Science categories.
Despite an increase in life expectancy over the past 20 years, the number of novel, multidrug resistant microorganisms has also risen dramatically. To reduce the risk of reemerging infections, and limit the spread of multidrug resistant microorganisms, it is urgently necessary to develop safe and effective therapeutic countermeasures. New antimicrobial chemicals are mostly produced with the help of microorganisms, and the bulk of medications now on the market are of this type. The use of high therapeutic screening and recent developments in analytical instrumentation has allowed the researchers to identify novel antimicrobial compounds from bacteria, fungi, plants, mushrooms, algae, and other sources more quickly. The second volume of Frontiers in Antimicrobial Agents highlights the ongoing requirement for researching and creating novel antimicrobial medications. Current Trends in the Identification and Development of Antimicrobial Agents aims to bring together the expertise of notable academics to examine all facets of antimicrobial research while keeping recent advancements in perspective. Antibiotic discovery, sources of novel antimicrobial chemicals, developing and reemerging microbial infections, various elements of drug resistance, and the need for antimicrobial medications in the future are all covered in this book. It is a timely reference for anyone involved in the discovery and development of new drugs, including microbiologists, biotechnologists, pharmacologists, doctors, and researchers.
Biopharmaceutical Informatics
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Author : Sandeep Kumar
language : en
Publisher: CRC Press
Release Date : 2025-01-22
Biopharmaceutical Informatics written by Sandeep Kumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-22 with Science categories.
Despite the phenomenal clinical success of antibody-based biopharmaceuticals in recent years, discovery and development of these novel biomedicines remains a costly, time-consuming, and risky endeavor with low probability of success. To bring better biomedicines to patients faster, we have come up with a strategic vision of Biopharmaceutical Informatics which calls for syncretic use of computation and experiment at all stages of biologic drug discovery and pre-clinical development cycles to improve probability of successful clinical outcomes. Biopharmaceutical Informatics also encourages industry and academic scientists supporting various aspects of biotherapeutic drug discovery and development cycles to learn from our collective experiences of successes and, more importantly, failures. The insights gained from such learnings shall help us improve the rate of successful translation of drug discoveries into drug products available to clinicians and patients, reduce costs, and increase the speed of biologic drug discovery and development. Hopefully, the efficiencies gained from implementing such insights shall make novel biomedicines more affordable for patients. This unique volume describes ways to invent and commercialize biomedicines more efficiently: Calls for digital transformation of biopharmaceutical industry by appropriately collecting, curating, and making available discovery and pre-clinical development project data using FAIR principles Describes applications of artificial intelligence and machine learning (AIML) in discovery of antibodies in silico (DAbI) starting with antigen design, constructing inherently developable antibody libraries, finding hits, identifying lead candidates, and optimizing them Details applications of AIML, physics-based computational design methods, and other bioinformatics tools in fields such as developability assessments, formulation and excipient design, analytical and bioprocess development, and pharmacology Presents pharmacokinetics/pharmacodynamics (PK/PD) and Quantitative Systems Pharmacology (QSP) models for biopharmaceuticals Describes uses of AIML in bispecific and multi-specific formats Dr Sandeep Kumar has also edited a collection of articles dedicated to this topic which can be found in the Taylor and Francis journal mAbs.
Multidisciplinary Research In Arts Science Commerce Volume 15
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Author : Chief Editor- Biplab Auddya, Editor- Dr. Bijikumary P, Dr. Pravin Vivek Kaslikar, Prof. Rohit Kulkarni, Mr. Enock I, Dr. J.Sathish Kumar, Dr. Balaji Shivraj Hokarne
language : en
Publisher: The Hill Publication
Release Date : 2024-12-19
Multidisciplinary Research In Arts Science Commerce Volume 15 written by Chief Editor- Biplab Auddya, Editor- Dr. Bijikumary P, Dr. Pravin Vivek Kaslikar, Prof. Rohit Kulkarni, Mr. Enock I, Dr. J.Sathish Kumar, Dr. Balaji Shivraj Hokarne and has been published by The Hill Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-19 with Antiques & Collectibles categories.
Computational Neuropharmacology
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Author : Bhupendra Prajapati
language : en
Publisher: John Wiley & Sons
Release Date : 2025-04-18
Computational Neuropharmacology written by Bhupendra Prajapati and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-18 with Science categories.
The book gives comprehensive insights into the cutting-edge intersection of computational methods and neuropharmacology, making it an essential resource for understanding and advancing medication for neurological and psychiatric disorders. Computational Neuropharmacology is an in-depth exploration of the convergence of computational methods with neuropharmacology, a science concerned with understanding pharmacological effects on the nervous system. This volume explores the most recent breakthroughs and potential advances in computational neuropharmacology, providing an extensive overview of the computational tools that are transforming medication discovery and development for neurological and psychiatric illnesses. Fundamental principles of computational neuropharmacology, descriptions of molecular-level interactions and their consequences for modern neuropharmacology, and an introduction to theoretical neuroscience are highlighted throughout this resource. Additionally, this study addresses computational attitudes in counseling psychology to improve therapeutic procedures through data-driven insights. Computational psychiatry uses computational technologies to bridge the gap between the molecular basis and clinical symptoms of psychiatric diseases. This volume covers computational approaches to drug discovery in neurohumoral transmission and signal transduction, Parkinson’s disease, epilepsy, and Alzheimer’s disease, and the use of molecular docking and machine learning in drug development for neurological disorders. It also discusses the use of computational methods to uncover potential treatments for autism spectrum disorder, depression, and anxiety. Audience This book is a valuable resource for computer scientists, engineers, researchers, clinicians, and students, providing a detailed understanding of the computational tools that are changing the developing field of neuropharmacology, leading the future of medication discovery and development for neurological and psychiatric illnesses by combining modern computational approaches with neuropharmacological research.