Directed Evolution For Development And Production Of Bioactive Agents


Directed Evolution For Development And Production Of Bioactive Agents
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Directed Evolution For Development And Production Of Bioactive Agents


Directed Evolution For Development And Production Of Bioactive Agents
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2013-05-15

Directed Evolution For Development And Production Of Bioactive Agents written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-15 with Political Science categories.


In 2012, the Defense Intelligence Agency (DIA) approached the National Research Council and asked that a committee be formed to develop a list of workshop topics to explore the impact of emerging science and technology. One topic that came out of that list was directed evolution for development and production of bioactive agents. This workshop was held on February 21-22, 2013. Directed Evolution for Development and Production of Bioactive Agents explains the objectives of the workshop, which were to explore the potential use of directed evolution1 for military science and technology. Understanding the current research in this area, and the potential opportunities for U.S. adversaries to use this research, might allow the DIA to advise U.S. policy makers in an appropriate and timely manner. The workshop featured invited presentations and discussions that aimed to: -Inform the U.S. intelligence community of the current status of directed evolution technology and related research, and -Discuss possible approaches involving directed evolution that might be used by an adversary to develop toxic biological agents that could pose a threat to the United States or its allies, and how they could be identified. Members of the Committee on Science and Technology for Defense Warning planned the agenda for the workshop, selected the presenters, and helped moderate discussions in which meeting participants probed issues of national security related to directed evolution in an effort to gain an understanding of potential vulnerabilities. Experts were invited from the areas of directed evolution, biosynthesis, detection, and biological agents.



Directed Evolution For Development And Production Of Bioactive Agents


Directed Evolution For Development And Production Of Bioactive Agents
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Author : Committee on Science and Technology for Defense Warning
language : en
Publisher: National Academies Press
Release Date : 2013-05-15

Directed Evolution For Development And Production Of Bioactive Agents written by Committee on Science and Technology for Defense Warning and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-15 with History categories.


In 2012, the Defense Intelligence Agency (DIA) approached the National Research Council and asked that a committee be formed to develop a list of workshop topics to explore the impact of emerging science and technology. One topic that came out of that list was directed evolution for development and production of bioactive agents. This workshop was held on February 21-22, 2013. Directed Evolution for Development and Production of Bioactive Agents explains the objectives of the workshop, which were to explore the potential use of directed evolution1 for military science and technology. Understanding the current research in this area, and the potential opportunities for U.S. adversaries to use this research, might allow the DIA to advise U.S. policy makers in an appropriate and timely manner. The workshop featured invited presentations and discussions that aimed to: -Inform the U.S. intelligence community of the current status of directed evolution technology and related research, and -Discuss possible approaches involving directed evolution that might be used by an adversary to develop toxic biological agents that could pose a threat to the United States or its allies, and how they could be identified. Members of the Committee on Science and Technology for Defense Warning planned the agenda for the workshop, selected the presenters, and helped moderate discussions in which meeting participants probed issues of national security related to directed evolution in an effort to gain an understanding of potential vulnerabilities. Experts were invited from the areas of directed evolution, biosynthesis, detection, and biological agents.



Recent Advances In Application Of Synthetic Biology For Production Of Bioactive Compounds


Recent Advances In Application Of Synthetic Biology For Production Of Bioactive Compounds
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Author : Luan Luong Chu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-09

Recent Advances In Application Of Synthetic Biology For Production Of Bioactive Compounds written by Luan Luong Chu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-09 with Science categories.




Biotechnological Production Of Bioactive Compounds


Biotechnological Production Of Bioactive Compounds
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Author : Madan L. Verma
language : en
Publisher: Elsevier
Release Date : 2019-07-20

Biotechnological Production Of Bioactive Compounds written by Madan L. Verma and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-20 with Technology & Engineering categories.


Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits “bioactives’’ from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. Outlines technological advances in bioactives extraction Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules



Evolutionary Diversity As A Source For Anticancer Molecules


Evolutionary Diversity As A Source For Anticancer Molecules
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Author : Akhileshwar Kumar Srivastava
language : en
Publisher: Academic Press
Release Date : 2020-09-21

Evolutionary Diversity As A Source For Anticancer Molecules written by Akhileshwar Kumar Srivastava and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-21 with Science categories.


Evolutionary Diversity as a Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes, and gymnosperms. The book goes over the isolation of anticancer agents and the technologyenabled screening process used to develop anticancer drugs. The book also includes discussion of the nutraceuticals and natural productsderived from invertebrates that can be used as part of cancer treatment. Evolutionary Diversity as a Source for Anticancer Molecules also deals with some of the current challenges in the prevention of cancer as well as the side effects of conventional drugs used for cancer patients.This book is a valuable resource for cancer researchers, oncologists, biotechnologists, pharmacologists, and any member of the biomedicalfield interested in understanding more about natural products with anticancer potential. Discusses the application of natural products in place of conventional drugs to minimize the side effects in cancer treatment Explains the relation between evolutionary mechanisms and climate change for production of secondary metabolites



Metabolic Engineering For Bioactive Compounds


Metabolic Engineering For Bioactive Compounds
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2017-10-07

Metabolic Engineering For Bioactive Compounds written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-07 with Medical categories.


This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.



Microbial Cell Factories Engineering For Production Of Biomolecules


Microbial Cell Factories Engineering For Production Of Biomolecules
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Author : Vijai Singh
language : en
Publisher: Academic Press
Release Date : 2021-02-13

Microbial Cell Factories Engineering For Production Of Biomolecules written by Vijai Singh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-13 with Science categories.


Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. Offers basic understanding and a clear picture of various MCFs Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications Highlights the advances, challenges, and future opportunities in designing MCFs



Biomass Biofuels Biochemicals


Biomass Biofuels Biochemicals
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Author : Ram Sarup Singh
language : en
Publisher: Elsevier
Release Date : 2019-03-04

Biomass Biofuels Biochemicals written by Ram Sarup Singh and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-04 with Technology & Engineering categories.


Biomass, Biofuels and Biochemicals: Advances in Enzyme Technology provides state-of-the-art information on the fundamental aspects and current perspectives in enzyme technology to graduate students, postgraduates and researchers working in industry and academia. The book provides information about the use of enzyme technology as an important tool for biotechnological processes, including food, feed, fuels, textiles, paper, energy and environmental applications. The search for improvements in existing enzyme-catalyzed processes dictates the need to update information on various enzyme technologies. The book gives a snapshot of current practice and research in the area of enzyme technology. Includes current and emerging technologies for the development of novel enzyme catalysis Outlines immobilized enzymes and their implications Refers to enzymes as diagnostic tools Includes metabolic engineering principles for improving industrial enzymes



Chemistry And Pharmacology Of Naturally Occurring Bioactive Compounds


Chemistry And Pharmacology Of Naturally Occurring Bioactive Compounds
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Author : Goutam Brahmachari
language : en
Publisher: CRC Press
Release Date : 2013-02-20

Chemistry And Pharmacology Of Naturally Occurring Bioactive Compounds written by Goutam Brahmachari and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-20 with Medical categories.


Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure–activity relationships.



Bioeconomy For Sustainable Development


Bioeconomy For Sustainable Development
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Author : Chetan Keswani
language : en
Publisher: Springer Nature
Release Date : 2019-10-14

Bioeconomy For Sustainable Development written by Chetan Keswani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-14 with Science categories.


The current era of incredible innovations has made science and technology one of the most powerful tools to meet the goals of incremental prosperity for humans and sustainable development. The development of the biotech industry in any given country is shaped by the characteristics of the technology—particularly its close relation to scientific knowledge—and by country-specific factors—the level and nature of the scientific knowledge base, the institutional set-up, and the role assumed by the government—which influence the country's ability to exploit new opportunities and appropriate the respective results. This book presents an integrated approach for sustained innovation in various areas of biotechnology. Focusing mainly on the industrial, socio-economic and legal implications of biotechnological advances, it examines in detail not only the implications of IPR in omics-based research but also the ethical and intellectual standards and how these can be developed for sustained innovation. Integrating science and business, it offers a peek behind the scenes of the biotech industry and provides a comprehensive analysis of the foundations of the present day industry for students and professionals alike. The book is divided into three parts: Food and Agricultural BiotechnologyIndustrial BiotechnologyPharmaceutical Biotechnology