Dopaminergic Mechanisms
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Dopaminergic Mechanisms
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Author : Donald Brian Calne
language : en
Publisher:
Release Date : 1975
Dopaminergic Mechanisms written by Donald Brian Calne and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Dopamine categories.
Dopaminergic Mechanisms In Vision
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Author : Marco Piccolino
language : en
Publisher:
Release Date : 1988
Dopaminergic Mechanisms In Vision written by Marco Piccolino and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
Dopaminergic Mechanisms In Vision
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Author : Bodis
language : en
Publisher: John Wiley & Sons
Release Date : 1988-01-01
Dopaminergic Mechanisms In Vision written by Bodis and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-01 with categories.
Studies On Key Developmental Regulatory Mechanisms Associated With Dopaminergic Neuron During Degeneration And Regeneration
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Author : Tippabathani Jayakrishna S
language : en
Publisher: Independent Author
Release Date : 2023-03-19
Studies On Key Developmental Regulatory Mechanisms Associated With Dopaminergic Neuron During Degeneration And Regeneration written by Tippabathani Jayakrishna S and has been published by Independent Author this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-19 with Education categories.
Dopamine (DA) is involved in many metabolic and regulating functions such as reward, motivation, memory, attention, and regulating body movements. In the mammalian central nervous system (CNS), mesencephalic dopaminergic (mDA) neurons are the main source of dopamine (Holzschuh et al., 2001). The selective loss of mDA neurons of the substantia nigra pars compacta (SNpc) is the hallmark of Parkinson's disease (PD) (DeMaagd and Philip, 2015). PD is associated with impairment of cognitive capabilities and symptoms like bradykinesia, tremor, and akinesia. Scientific reports are working to decipher the cellular and molecular mechanisms driving PD pathogenesis, as it is not well understood. Symptoms manifest only after 70-80% of mDA neurons have been degenerated (Cheng et al., 2010) and may be devastating because the adult CNS has extremely limited intrinsic regeneration to replace the lost neurons (Horner and Gage, 2000). Unfortunately, the loss of DA neurons cannot be rescued or reversed by drug administration. It is mandatory to decipher the neurogenesis and their mechanism, as they assist the scientific community towards inducing human stem cells to express a dopaminergic phenotype.
Dopaminergic Neuron Transplantation In The Weaver Mouse Model Of Parkinson S Disease
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Author : Lazaros Triarhou
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-01-31
Dopaminergic Neuron Transplantation In The Weaver Mouse Model Of Parkinson S Disease written by Lazaros Triarhou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-31 with Medical categories.
Parkinson's disease, a degenerative brain disorder, affects an estimated 0.25-0.50% of the population. Symptoms result from neuronal degeneration in the nigrostriatal dopaminergic pathway and include tremor, rigidity and gradual slow- ness of spontaneous movement. The cause of Parkinson's disease is only partially understood; both environmental factors and a genetic predisposition have been im- plicated in its etiopathogenesis. Neural transplantation is being used experimentally for providing an alternative biological source of dopamine both in animal studies and in experimental clinical trials. This book is the result of 15 years of research on the transplantation of dopaminergic neurons in the striatum of the weaver mouse, a neurological mutant characterized by genetically-determined degeneration of midbrain dopamine neurons. The weaver mouse constitutes the only available laboratory model with a chronic progressive disease that mimics Parkinsonism. The other two models currently used to investigate dopaminergic mechanisms rely on the use of the neurotoxins- hydroxydopamine and methylphenyltetrahydropyridine for the selective removal of dopaminergic neurons from an otherwise healthy organism. Structural and functional aspects of transplantation of mesencephalic dopamin- ergic grafts into the striatum of weaver mice are reviewed, including histochemical correlates of graft survival and integration, numerical aspects of donor neuron survival, ultrastructural findings on synaptogenesis, neurochemical indices of dopam- ine uptake function and receptor binding, gene expression of several structural and neurotransmitter-receptor related molecules, the levels of striatal amino acid receptors, and the behavioral effects of unilateral and bilateral neuronal transplantations.
Mechanisms Of Degeneration And Protection Of The Dopaminergic System
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Author : Juan Segura-Aguila
language : en
Publisher: F P Graham Company
Release Date : 2001-01-01
Mechanisms Of Degeneration And Protection Of The Dopaminergic System written by Juan Segura-Aguila and has been published by F P Graham Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-01 with Dopamine categories.
Dopamine
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Author : Endo Kudo
language : en
Publisher:
Release Date : 2012
Dopamine written by Endo Kudo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Dopamine categories.
In this book, the authors present current research in the functions, regulation and health effects of dopamine. Topics include N-Acylated dopamine; the molecular and genetic basis of the regulation of dopamine transporter; dopaminergic and glutamatergic dysfunctions in the neuropathophysiology of schizophrenia; regulation of synapsin II by dopaminergic mechanisms; dopamine agonists and paraphilias and gene therapy for continuous dopamine production in Parkinson's disease. (Imprint: Nova Biomedical)
Lisuride And Other Dopamine Agonists
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Author : Donald Brian Calne
language : en
Publisher: Raven Press (ID)
Release Date : 1983
Lisuride And Other Dopamine Agonists written by Donald Brian Calne and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
Dopamine
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Author :
language : en
Publisher: Elsevier
Release Date : 2014-06-23
Dopamine written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-23 with Science categories.
Progress in Brain Research is a well-established international series examining major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume, concentrates on state-of-the-art of dopamine research: from basic science to clinical applications. It covers topics including thalamostriatal synapses as a substrate for dopamine action; the multilingual nature of dopamine neurons; ethanol-mechanisms along the mesolimbic dopamine system, and much more.Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry, and the behavioral sciences. The most acclaimed and accomplished series in neuroscience This volume looks at dopamine research in the light of the newest scholarly discoveries and insights
Dopamine In The Cns Ii
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Author : Gaetano Di Chiara
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Dopamine In The Cns Ii written by Gaetano Di Chiara and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
With contributions by numerous experts
