Dynamic Models For Structural Plasticity
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Dynamic Models For Structural Plasticity
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Author : William J. Stronge
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Dynamic Models For Structural Plasticity written by William J. Stronge and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
Our topic is irreversible or plastic deformation of structural elements composed of relatively thin ductile materials. These deformations are commonly used in sheet metal forming operations to produce lightweight parts of any particular shape. In another context, this type of plastic deformation is described as impact damage in the case of structural components involved in collision. Here we are concerned with mechanics of both static and dynamic deformation processes. The purpose is to use typical material properties and structural characteristics to calculate the deformation for certain types of load; in particular to find the final deflection and shape of the deformed structure and to illustrate how the development of this final shape depends on the constitutive model used to represent the material behavior. The major issue to be addressed is which structural and constitutive properties are important for calculating response to either static or brief but intense dynamic loads. Furthermore, how do the results of various constitutive models compare with observed behavior.
Anatomy And Plasticity In Large Scale Brain Models
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Author : Markus Butz
language : en
Publisher: Frontiers Media SA
Release Date : 2017-01-05
Anatomy And Plasticity In Large Scale Brain Models written by Markus Butz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-05 with categories.
Supercomputing facilities are becoming increasingly available for simulating activity dynamics in large-scale neuronal networks. On today's most advanced supercomputers, networks with up to a billion of neurons can be readily simulated. However, building biologically realistic, full-scale brain models requires more than just a huge number of neurons. In addition to network size, the detailed local and global anatomy of neuronal connections is of crucial importance. Moreover, anatomical connectivity is not fixed, but can rewire throughout life (structural plasticity)—an aspect that is missing in most current network models, in which plasticity is confined to changes in synaptic strength (synaptic plasticity). The papers in this Ebook, which may broadly be divided into three themes, aim to bring together high-performance computing with recent experimental and computational research in neuroanatomy. In the first theme (fiber connectivity), new methods are described for measuring and data-basing microscopic and macroscopic connectivity. In the second theme (structural plasticity), novel models are introduced that incorporate morphological plasticity and rewiring of anatomical connections. In the third theme (large-scale simulations), simulations of large-scale neuronal networks are presented with an emphasis on anatomical detail and plasticity mechanisms. Together, the articles in this Ebook make the reader aware of the methods and models by which large-scale brain networks running on supercomputers can be extended to include anatomical detail and plasticity.
Synaptic Plasticity In Neurodegenerative Disorders
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Author : Sangeeta Singh
language : en
Publisher: CRC Press
Release Date : 2024-12-24
Synaptic Plasticity In Neurodegenerative Disorders written by Sangeeta Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Science categories.
This book explores the pivotal role of synaptic plasticity in the pathogenesis, progression, and potential treatment of neurodegenerative disorders. The initial chapter provides an in-depth understanding of the complexity and impact of neurodegenerative conditions. It discusses the association of mitochondrial dysfunction, epigenetic influences, and neuroinflammation with synaptic plasticity in neurodegenerative diseases. The following chapters review the dynamic changes that occur at the cellular and synaptic levels in Parkinson's disease, Alzheimer's disease, and Huntington's disease, paving the way for innovative therapeutic strategies. Furthermore, the book presents various computational tools and methodologies essential for enhancing our understanding of synaptic plasticity. It examines the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases. Discusses the role of synaptic plasticity in neurodegenerative diseases, shedding light on how dynamic changes occur at the cellular and synaptic levels Explores the transformative role of artificial intelligence tools in addressing synaptic impairment across various neurodegenerative diseases Provides a comprehensive overview of neurodegenerative disorders, including pathogenesis, etiology, and treatment strategies Presents tools and techniques used to simulate the complex system biology of synaptic plasticity Examines the role of computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis Toward the end, the book explores the role of synaptic impairment and computational neuroscience in understanding and potentially treating conditions such as multiple sclerosis and amyotrophic lateral sclerosis. With its multifaceted approach, this book serves as a useful resource for researchers, clinicians, and students in the fields of neuroscience, computational biology, and neurology.
Nonlinear Dynamics Of Structures Under Extreme Transient Loads
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Author : Adnan Ibrahimbegovic
language : en
Publisher: CRC Press
Release Date : 2019-05-21
Nonlinear Dynamics Of Structures Under Extreme Transient Loads written by Adnan Ibrahimbegovic and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-21 with Technology & Engineering categories.
The effect of combined extreme transient loadings on a structure is not well understood—whether the source is man-made, such as an explosion and fire, or natural, such as an earthquake or extreme wind loading. A critical assessment of current knowledge is timely (with Fukushima-like disasters or terrorist threats). The central issue in all these problems is structural integrity, along with their transient nature, their unexpectedness, and often the uncertainty behind their cause. No single traditional scientific discipline provides complete answers, rather, a number of tools need to be brought together: nonlinear dynamics, probability theory, some understanding of the physical nature of the problem, as well as modeling and computational techniques for representing inelastic behavior mechanisms. Nonlinear Dynamics of Structures Under Extreme Transient Loads covers model building for different engineering structures and provides detailed presentations of extreme loading conditions. A number of illustrations are given quantifying; a plane crash or explosion induced impact loading, the effects of strong earthquake motion, and the impact and long-duration effects of strong stormy winds—along with a relevant framework for using modern computational tools. The book considers the levels of reserve in existing structures, and ways of reducing the negative impact of high-risk situations by employing sounder design procedures.
Rock Mechanics Achievements And Ambitions
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Author : Meifeng Cai
language : en
Publisher: CRC Press
Release Date : 2011-09-22
Rock Mechanics Achievements And Ambitions written by Meifeng Cai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-22 with Technology & Engineering categories.
The present work provides an important stimulus for the next generation of rock engineers, because in the future there will be more emphasis on the use of the Earth's resources and their sustainability, and more accountability of engineers' decisions. The increasing energy demand will be met by the continued operation and development of new coal mines, hydroelectric plants and nuclear power stations with one or more underground nuclear waste repositories. In particular, enhanced methods of site investigation, rock characterisation, rock failure understanding, computer modelling, and rock excavation and support are needed. Many of the 200 papers indicate that we can be confident in the continuing development of rock mechanics and r
The Functional Role Of Critical Dynamics In Neural Systems
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Author : Nergis Tomen
language : en
Publisher: Springer
Release Date : 2019-07-23
The Functional Role Of Critical Dynamics In Neural Systems written by Nergis Tomen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Science categories.
This book offers a timely overview of theories and methods developed by an authoritative group of researchers to understand the link between criticality and brain functioning. Cortical information processing in particular and brain function in general rely heavily on the collective dynamics of neurons and networks distributed over many brain areas. A key concept for characterizing and understanding brain dynamics is the idea that networks operate near a critical state, which offers several potential benefits for computation and information processing. However, there is still a large gap between research on criticality and understanding brain function. For example, cortical networks are not homogeneous but highly structured, they are not in a state of spontaneous activation but strongly driven by changing external stimuli, and they process information with respect to behavioral goals. So far the questions relating to how critical dynamics may support computation in this complex setting, and whether they can outperform other information processing schemes remain open. Based on the workshop “Dynamical Network States, Criticality and Cortical Function", held in March 2017 at the Hanse Institute for Advanced Studies (HWK) in Delmenhorst, Germany, the book provides readers with extensive information on these topics, as well as tools and ideas to answer the above-mentioned questions. It is meant for physicists, computational and systems neuroscientists, and biologists.
Applied Mechanics Reviews
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Author :
language : en
Publisher:
Release Date : 1995
Applied Mechanics Reviews written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Mechanics, Applied categories.
Validating Neuro Computational Models Of Neurological And Psychiatric Disorders
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Author : Basabdatta Sen Bhattacharya
language : en
Publisher: Springer
Release Date : 2015-10-30
Validating Neuro Computational Models Of Neurological And Psychiatric Disorders written by Basabdatta Sen Bhattacharya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-30 with Medical categories.
This book is a collection of articles by leading researchers working at the cutting edge of neuro-computational modelling of neurological and psychiatric disorders. Each article contains model validation techniques used in the context of the specific problem being studied. Validation is essential for neuro-inspired computational models to become useful tools in the understanding and treatment of disease conditions. Currently, the immense diversity in neuro-computational modelling approaches for investigating brain diseases has created the need for a structured and coordinated approach to benchmark and standardise validation methods and techniques in this field of research. This book serves as a step towards a systematic approach to validation of neuro-computational models used for studying brain diseases and should be useful for all neuro-computational modellers.
Self Organized Criticality Three Decades Later
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Author : Subhrangshu Sekhar Manna
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-28
Self Organized Criticality Three Decades Later written by Subhrangshu Sekhar Manna and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-28 with Science categories.
Structures Under Shock And Impact Xii
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Author : G. Schleyer
language : en
Publisher: WIT Press
Release Date : 2013
Structures Under Shock And Impact Xii written by G. Schleyer and has been published by WIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Technology & Engineering categories.
Of interest to engineers from civil, military, nuclear, offshore, aeronautical, transportation and other backgrounds, this book contains the proceedings of a well-established conference on the subject that was first held in 1989. Topics covered include: Impact and Blast Loading Characteristics; Protection of Structures from Blast Loads; Energy Absorbing Issues; Structural Crashworthiness; Hazard Mitigation and Assessment; Behaviour of Steel Structures; Behaviour of Structural Concrete; Material Response to High Rate Loading; Seismic Engineering Applications; Interaction Between Computational and Experimental Results; Innovative Materials and Material Systems; Fluid Structure Interaction.The shock and impact behaviour of structures presents challenges to researchers not only because it has obvious time-dependent aspects, but also because it is difficult to specify the external dynamic loading characteristics and to obtain the full dynamic properties of materials. It is crucial that we find ways to share the contributions and understanding that are developing from various theoretical, numerical and experimental studies, as well as investigations into material properties under dynamic loading conditions. This book helps to meet that need.