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Dynamic Regression Models For Survival Data


Dynamic Regression Models For Survival Data
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Dynamic Regression Models For Survival Data


Dynamic Regression Models For Survival Data
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Author : Torben Martinussen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-24

Dynamic Regression Models For Survival Data written by Torben Martinussen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-24 with Medical categories.


This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and alternative models with the aim of describing time-varying effects of explanatory variables. Use of the suggested models and methods is illustrated on real data examples, using the R-package timereg developed by the authors, which is applied throughout the book with worked examples for the data sets.



Dynamic Prediction In Clinical Survival Analysis


Dynamic Prediction In Clinical Survival Analysis
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Author : Hans van Houwelingen
language : en
Publisher: CRC Press
Release Date : 2011-11-09

Dynamic Prediction In Clinical Survival Analysis written by Hans van Houwelingen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-09 with Mathematics categories.


There is a huge amount of literature on statistical models for the prediction of survival after diagnosis of a wide range of diseases like cancer, cardiovascular disease, and chronic kidney disease. Current practice is to use prediction models based on the Cox proportional hazards model and to present those as static models for remaining lifetime after diagnosis or treatment. In contrast, Dynamic Prediction in Clinical Survival Analysis focuses on dynamic models for the remaining lifetime at later points in time, for instance using landmark models. Designed to be useful to applied statisticians and clinical epidemiologists, each chapter in the book has a practical focus on the issues of working with real life data. Chapters conclude with additional material either on the interpretation of the models, alternative models, or theoretical background. The book consists of four parts: Part I deals with prognostic models for survival data using (clinical) information available at baseline, based on the Cox model Part II is about prognostic models for survival data using (clinical) information available at baseline, when the proportional hazards assumption of the Cox model is violated Part III is dedicated to the use of time-dependent information in dynamic prediction Part IV explores dynamic prediction models for survival data using genomic data Dynamic Prediction in Clinical Survival Analysis summarizes cutting-edge research on the dynamic use of predictive models with traditional and new approaches. Aimed at applied statisticians who actively analyze clinical data in collaboration with clinicians, the analyses of the different data sets throughout the book demonstrate how predictive models can be obtained from proper data sets.



Dynamic Prediction In Clinical Survival Analysis


Dynamic Prediction In Clinical Survival Analysis
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Author : Hans van Houwelingen
language : en
Publisher: CRC Press
Release Date : 2011-11-09

Dynamic Prediction In Clinical Survival Analysis written by Hans van Houwelingen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-09 with Mathematics categories.


There is a huge amount of literature on statistical models for the prediction of survival after diagnosis of a wide range of diseases like cancer, cardiovascular disease, and chronic kidney disease. Current practice is to use prediction models based on the Cox proportional hazards model and to present those as static models for remaining lifetime after diagnosis or treatment. In contrast, Dynamic Prediction in Clinical Survival Analysis focuses on dynamic models for the remaining lifetime at later points in time, for instance using landmark models. Designed to be useful to applied statisticians and clinical epidemiologists, each chapter in the book has a practical focus on the issues of working with real life data. Chapters conclude with additional material either on the interpretation of the models, alternative models, or theoretical background. The book consists of four parts: Part I deals with prognostic models for survival data using (clinical) information available at baseline, based on the Cox model Part II is about prognostic models for survival data using (clinical) information available at baseline, when the proportional hazards assumption of the Cox model is violated Part III is dedicated to the use of time-dependent information in dynamic prediction Part IV explores dynamic prediction models for survival data using genomic data Dynamic Prediction in Clinical Survival Analysis summarizes cutting-edge research on the dynamic use of predictive models with traditional and new approaches. Aimed at applied statisticians who actively analyze clinical data in collaboration with clinicians, the analyses of the different data sets throughout the book demonstrate how predictive models can be obtained from proper data sets.



Forecasting With Dynamic Regression Models


Forecasting With Dynamic Regression Models
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Author : Alan Pankratz
language : en
Publisher: John Wiley & Sons
Release Date : 2012-01-20

Forecasting With Dynamic Regression Models written by Alan Pankratz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-20 with Mathematics categories.


One of the most widely used tools in statistical forecasting, single equation regression models is examined here. A companion to the author's earlier work, Forecasting with Univariate Box-Jenkins Models: Concepts and Cases, the present text pulls together recent time series ideas and gives special attention to possible intertemporal patterns, distributed lag responses of output to input series and the auto correlation patterns of regression disturbance. It also includes six case studies.



Applied Survival Analysis


Applied Survival Analysis
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Author : David W. Hosmer, Jr.
language : en
Publisher: John Wiley & Sons
Release Date : 2008-03-07

Applied Survival Analysis written by David W. Hosmer, Jr. and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-07 with Mathematics categories.


THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.



Handbook Of Survival Analysis


Handbook Of Survival Analysis
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Author : John P. Klein
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Handbook Of Survival Analysis written by John P. Klein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.


Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians



The Statistical Analysis Of Recurrent Events


The Statistical Analysis Of Recurrent Events
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Author : Richard J. Cook
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-02

The Statistical Analysis Of Recurrent Events written by Richard J. Cook and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-02 with Medical categories.


This book presents models and statistical methods for the analysis of recurrent event data. The authors provide broad, detailed coverage of the major approaches to analysis, while emphasizing the modeling assumptions that they are based on. More general intensity-based models are also considered, as well as simpler models that focus on rate or mean functions. Parametric, nonparametric and semiparametric methodologies are all covered, with procedures for estimation, testing and model checking.



Bayesian Forecasting And Dynamic Models


Bayesian Forecasting And Dynamic Models
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Author : Mike West
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Bayesian Forecasting And Dynamic Models written by Mike West and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Mathematics categories.


In this book we are concerned with Bayesian learning and forecast ing in dynamic environments. We describe the structure and theory of classes of dynamic models, and their uses in Bayesian forecasting. The principles, models and methods of Bayesian forecasting have been developed extensively during the last twenty years. This devel opment has involved thorough investigation of mathematical and sta tistical aspects of forecasting models and related techniques. With this has come experience with application in a variety of areas in commercial and industrial, scientific and socio-economic fields. In deed much of the technical development has been driven by the needs of forecasting practitioners. As a result, there now exists a relatively complete statistical and mathematical framework, although much of this is either not properly documented or not easily accessible. Our primary goals in writing this book have been to present our view of this approach to modelling and forecasting, and to provide a rea sonably complete text for advanced university students and research workers. The text is primarily intended for advanced undergraduate and postgraduate students in statistics and mathematics. In line with this objective we present thorough discussion of mathematical and statistical features of Bayesian analyses of dynamic models, with illustrations, examples and exercises in each Chapter.



Survival And Event History Analysis


Survival And Event History Analysis
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Author : Odd Aalen
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-09-16

Survival And Event History Analysis written by Odd Aalen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-16 with Mathematics categories.


The aim of this book is to bridge the gap between standard textbook models and a range of models where the dynamic structure of the data manifests itself fully. The common denominator of such models is stochastic processes. The authors show how counting processes, martingales, and stochastic integrals fit very nicely with censored data. Beginning with standard analyses such as Kaplan-Meier plots and Cox regression, the presentation progresses to the additive hazard model and recurrent event data. Stochastic processes are also used as natural models for individual frailty; they allow sensible interpretations of a number of surprising artifacts seen in population data. The stochastic process framework is naturally connected to causality. The authors show how dynamic path analyses can incorporate many modern causality ideas in a framework that takes the time aspect seriously. To make the material accessible to the reader, a large number of practical examples, mainly from medicine, are developed in detail. Stochastic processes are introduced in an intuitive and non-technical manner. The book is aimed at investigators who use event history methods and want a better understanding of the statistical concepts. It is suitable as a textbook for graduate courses in statistics and biostatistics.



The Frailty Model


The Frailty Model
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Author : Luc Duchateau
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-23

The Frailty Model written by Luc Duchateau and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-23 with Mathematics categories.


Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clustered survival data. In contrast to the large number of research publications on frailty models, relatively few statistical software packages contain frailty models. It is demanding for statistical practitioners and graduate students to grasp a good knowledge on frailty models from the existing literature. This book provides an in-depth discussion and explanation of the basics of frailty model methodology for such readers. The discussion includes parametric and semiparametric frailty models and accelerated failure time models. Common techniques to fit frailty models include the EM-algorithm, penalised likelihood techniques, Laplacian integration and Bayesian techniques. More advanced frailty models for hierarchical data are also included. Real-lifeexamples are used to demonstrate how particular frailty models can be fitted and how the results should be interpreted. The programs to fit all the worked-out examples in the book are available from the Springer website with most of the programs developed in the freeware packages R and Winbugs. The book starts with a brief overview of some basic concepts in classical survival analysis, collecting what is needed for the reading on the more complex frailty models.