Emerging Concepts In Ribosome Structure Biogenesis And Function
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Emerging Concepts In Ribosome Structure Biogenesis And Function
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Author : Vijay Kumar
language : en
Publisher: Academic Press
Release Date : 2021-09-25
Emerging Concepts In Ribosome Structure Biogenesis And Function written by Vijay Kumar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-25 with Science categories.
Ribosome biogenesis is the process of making ribosomes which are responsible for mRNA translation into proteins. It is a tightly regulated process closely linked to nearly all biochemical and cellular processes, including cell division, growth, and development. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides a synthesized overview of all the parts engaged in this process. The book begins by providing an introduction to the ribosome factory, its origin, and its evolution of translation. It then goes on to describe ribosome structure including subunits, RNA, and protein components. Ribosome biogenesis and its emergence as a frontier research area for translational potential in cancer and other diseases are also discussed. In addition, the book explores current developments in ribosome research like the emergence of ribosomopathies, how deregulation of ribosome biogenesis can impact disease mechanisms and aging, and the discovery of specialized ribosomes that have specific functions that may translate differentially with consequences on normal and pathological processes. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides fundamental coverage and emerging research on ribosomes, biogenesis, and their structure and function and is a resourceful introduction for new researchers and those engaged in interdisciplinary ribosomal research. - Provides an overview of ribosome biogenesis and examines its involvement in cell transformation and cancerous growth - Covers disorders related to the ribosome (ribosomopathies) and explains the significance of ribosome dysfunction in human diseases - Includes commonly used methods to study ribosomes, such as polysome preparation, RNA profiling and proteomics, CryoEM, and Cell-free assays along with proper illustrations
Mitochondrial Oxphos System Emerging Concepts And Technologies And Role In Disease
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Author : David Pacheu-Grau
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-06
Mitochondrial Oxphos System Emerging Concepts And Technologies And Role In Disease written by David Pacheu-Grau and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-06 with Science categories.
New Concepts Of Antiviral Therapy
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Author : Elke Bogner
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-31
New Concepts Of Antiviral Therapy written by Elke Bogner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-31 with Science categories.
Antiviral drugs are important tools for treatment or prevention of viral infections. These drugs were first used for monotherapy, but nowadays combinations of antiviral agents are often part of a standard treatment as evidenced by e.g. HAART (highly active antiretroviral therapy). However, in almost every case of antiviral therapy, drug resistant viruses appear. In addition, the low oral bioavailability, toxicity and the number of severe side effects still pose significant problems. All of the latter issues limit the clinical usefulness and drive the need for improved antiviral strategies. These strategies include new drugs and targets, novel modes of action, vector-based treatments and even the block of defined genes by inhibiting mRNA formation (siRNA). Highlights of this book include the discussion of: - novel, promising compounds - concepts of therapy for new/emerging viruses - managing drug resistance - new therapeutic strategies This book presents an overview of the most recent developments. Contributions were carefully selected to ensure quality coverage by acknowledged experts over a wide spectrum and should prove to be of great value to students and serve as a compendium for R and D and educational professionals.
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1971
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medicine categories.
International Review Of Cell And Molecular Biology
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Author : Kwang W. Jeon
language : en
Publisher: Academic Press
Release Date : 2010-11-19
International Review Of Cell And Molecular Biology written by Kwang W. Jeon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-19 with Science categories.
International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2008: 4.935. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists
The Biogenesis Of Cellular Organelles
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Author : Chris Mullins
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-06
The Biogenesis Of Cellular Organelles written by Chris Mullins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Medical categories.
The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by describing past scientific strategies, theories, and findings and relating these foundations to current investigations. Reviews of protein and lipid mediators important for organelle biogenesis are then presented, and are followed by summaries focused on the endoplasmic reticulum, Golgi, lysosome, nucleus, mitochondria, and peroxisome.
The Nucleolus
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Author : Mark O. J. Olson
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-15
The Nucleolus written by Mark O. J. Olson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-15 with Science categories.
Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1982
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medicine categories.
Archaeal Ribosomes Biogenesis Structure And Function
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Author : Paola Londei
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-24
Archaeal Ribosomes Biogenesis Structure And Function written by Paola Londei and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Science categories.
Cryo Electron Microscopy In Structural Biology
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Author : Krishnarao Appasani
language : en
Publisher: CRC Press
Release Date : 2024-10-17
Cryo Electron Microscopy In Structural Biology written by Krishnarao Appasani and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-17 with Science categories.
Cryo-electron microscopy, in combination with tomography, has emerged as a new technology for visualizing molecular structures at a resolution beyond even 1 Å. Using this technology has revealed the native molecular details of viruses, membranes, enzymes, ribosomes, and cells. This comprehensive volume brings together authoritative overviews of these methods from structural and biological perspectives. It is a must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, structural biology, crystallography, and genomics. Key Features • Focuses on the applications of cryo-EM to structural biology • Documents the importance of cryo-EM/ET approaches in studying the structural determinants of cellular organelle and membrane protein biochemistry • Reviews the applications of high-resolution structures of viruses • Emphasizes structural insights of nuclear and gene machineries • Includes a section focused entirely on the applications of cryo-EM/ET in drug discovery and therapeutic development