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Epithelial Transport Physiology


Epithelial Transport Physiology
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Epithelial Transport Physiology


Epithelial Transport Physiology
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Author : George A. Gerencser
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10

Epithelial Transport Physiology written by George A. Gerencser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Science categories.


Biological cell membranes regulate the transfer of matter and information between the intracellular and extracellular compartments as basic survival and maintenance functions for an organism. This volume contains a series of reviews that are c- cerned with how epithelial plasma membranes regulate the transport of solutes between the intracellular and extracellular compartments of a cell. This book is also an attempt to analyze the molecular basis for the movement of various solutes across an epithelial cell membrane. This volume is devoted to a diversity of epithelial transport mechanisms in rep- sentative cell membranes of a variety of living things. The ?rst section of the book (Chapters 1–6) focuses on mechanisms of solute transport in epithelia of inver- brates. The last section which comprises ten chapters (Chapters 7–16) deals with solute transporters in epithelial cell membranes of vertebrates. It is hoped that with this particular ordering the reader can glean a telescopic view of the evolutionary history of the various epithelial solute transporters.



Basic Epithelial Ion Transport Principles And Function


Basic Epithelial Ion Transport Principles And Function
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Author : Kirk L. Hamilton
language : en
Publisher: Springer Nature
Release Date : 2020-11-26

Basic Epithelial Ion Transport Principles And Function written by Kirk L. Hamilton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-26 with Medical categories.


This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.



Epithelial Transport


Epithelial Transport
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Author : N.K. Wills
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Epithelial Transport written by N.K. Wills and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Building from general principles, the authors clearly explain the fundamental role of epithelia in plasma electrolyte and water balance. Emphasis is placed on experimental approaches and methodology. A comprehensive glossary of terms is included.



Epithelial Transport Physiology


Epithelial Transport Physiology
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Author :
language : en
Publisher:
Release Date : 2011-07

Epithelial Transport Physiology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07 with categories.




Transporting Epithelia


Transporting Epithelia
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Author : Michael Berridge
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Transporting Epithelia written by Michael Berridge and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Transporting Epithelia summarizes the progress that has been made in understanding a wide range of epithelial transport systems. This book discusses the epithelia involved in osmotic and ionic regulation from protonephridia to the mammalian kidney. It also explains the digestive and absorptive epithelia, as well as the epithelia that produce special secretions, such as milk, endolymph, aqueous humor, cerebrospinal fluid, sweat, and tears. Furthermore, this book describes the role of the epithelium in the physiology of the animal and the structure of the epithelium. Then, the structure of the epithelium is correlated with its physiological properties. This book will be valuable both for teaching and as a reference for research workers interested in comparative aspects of transport phenomena.



Ion Channels And Transporters Of Epithelia In Health And Disease


Ion Channels And Transporters Of Epithelia In Health And Disease
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Author : Kirk L. Hamilton
language : en
Publisher: Springer
Release Date : 2015-12-14

Ion Channels And Transporters Of Epithelia In Health And Disease written by Kirk L. Hamilton and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-14 with Medical categories.


This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.



Nacl Transport In Epithelia


Nacl Transport In Epithelia
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Author : R. Greger
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Nacl Transport In Epithelia written by R. Greger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia. This aspect triggered the publica tion of this book, and in fact the various chapters emphasize that the funetional eomponents, expressed in the various epithelia, are not in finite in number, but they occur in epithelia which are separated in evolu tion by several hundred million years. The authors come both from the field of veterinary and human physiology as weIl as from biology. In my opinion, the close contacts and eollaborations between physiologists and biologists have been essential for the progress in this field. I wish to thank all authors for their con tributions, and I hope that the reader will appreciate this collection of up to date reviews on epithelia in nonvertebrates and vertebrates.



Ion Transport Across Epithelial Tissues And Disease


Ion Transport Across Epithelial Tissues And Disease
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Author : Kirk L. Hamilton
language : en
Publisher: Springer Nature
Release Date : 2020-12-12

Ion Transport Across Epithelial Tissues And Disease written by Kirk L. Hamilton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-12 with Medical categories.


This book discusses the unique ion channels and transporters found within the epithelial tissues of various organs, including the kidney, intestine, pancreas and respiratory tract. Authors focus on demonstrating the crucial roles that each of these channels and transporters play in transepithelial ion and fluid transport across epithelia, as well as in maintaining homeostasis. It allows readers to gain an understanding of the fundamentals of ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the second of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on a wide array of epithelial tissues and the use of organoids to study epithelial function. Furthermore, clinical researchers and basic scientists from various fields provide a medical perspective on the physiology of a number of tissues and organs of the body including the pancreas, intestine, sweat glands, mammary gland, inner ear epithelia, retinal pigment epithelia of the eye, choroid plexus, and the ectodermal epithelia in dental enamel formation. This volume aims to ‘round out’ the reader’s journey from basic science to the laboratory bench and clinical management of molecular diseases, making Volume 2 a must-read for students and scientists in the field of physiology, as well as for clinicians.



Studies Of Epithelial Transporters And Ion Channels


Studies Of Epithelial Transporters And Ion Channels
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Author : Kirk L. Hamilton
language : en
Publisher: Springer Nature
Release Date : 2021-03-04

Studies Of Epithelial Transporters And Ion Channels written by Kirk L. Hamilton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-04 with Medical categories.


This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.



Nacl Transport In Epithelia


Nacl Transport In Epithelia
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Author : R. Greger
language : en
Publisher: Springer
Release Date : 1988-05-30

Nacl Transport In Epithelia written by R. Greger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-05-30 with Science categories.


After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia. This aspect triggered the publica tion of this book, and in fact the various chapters emphasize that the funetional eomponents, expressed in the various epithelia, are not in finite in number, but they occur in epithelia which are separated in evolu tion by several hundred million years. The authors come both from the field of veterinary and human physiology as weIl as from biology. In my opinion, the close contacts and eollaborations between physiologists and biologists have been essential for the progress in this field. I wish to thank all authors for their con tributions, and I hope that the reader will appreciate this collection of up to date reviews on epithelia in nonvertebrates and vertebrates.