Establishing And Maintaining Cell Polarity
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Establishing And Maintaining Cell Polarity
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Author : Benjamin Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-22
Establishing And Maintaining Cell Polarity written by Benjamin Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Science categories.
Polarity In Plants
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Author : K. Lindsey
language : en
Publisher: John Wiley & Sons
Release Date : 2004
Polarity In Plants written by K. Lindsey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.
The establishment of polarity is a fundamental feature in eukaryotic development. Polarity in Plants provides an account of current research into the mechanisms by which polarity is generated at the level of the cell, organ and organism in plants, drawing especially on recent work with model organisms. The emphasis is on the use of the techniques of molecular genetics to dissect molecular mechanisms. This is the first volume to bring together the diverse aspects of polarity in plant development.
The Cytoskeleton
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Author : James Spudich
language : en
Publisher:
Release Date : 1996
The Cytoskeleton written by James Spudich and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Actin categories.
Neuronal Polarity Establishment And Maintenance
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Author : Froylan Calderon de Anda
language : en
Publisher: Frontiers Media SA
Release Date : 2018-07-12
Neuronal Polarity Establishment And Maintenance written by Froylan Calderon de Anda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-12 with categories.
The term polarity in a biological context is used to describe an asymmetry in morphology and distribution of molecules. In neurons, their complex shape with typically one axon and several dendrites reflects this asymmetry. Although neurons assume many different shapes and sizes they always maintain these two domains, which are essential for neuronal function. In the most simple view, neurons use their axon to transmit signals over long distances due to its capacity to extend to enormous lengths. Dendrites, on the other hand, are shorter and receive and integrate signals from different locations. The selection of the site where the axon and dendrites initially emerge during embryonic development is a tightly regulated event, eventually important for the correct formation of neuronal circuits, and disturbances of these processes can have pathological consequences due to circuit malformation. An important question is which mechanisms neurons utilize to specify the sites where axonal and dendrite outgrowth occurs and how their identities are maintained during and after development. The formation of these functionally diverse domains is the result of polarized differences of membrane and protein delivery, mitochondria transport, actin dynamics and microtubule stability. However how and in which temporal order all those events which coordinate the selection and maintenance of axons and dendrites is still under investigation. This selection of articles shall highlight new findings, which help to unravel all molecular and cellular events important for neuronal polarity establishment and maintenance.
Trafficking Inside Cells
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Author : Nava Segev
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-30
Trafficking Inside Cells written by Nava Segev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-30 with Science categories.
This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.
Cell Polarity
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Author : J.R. Bartles
language : en
Publisher: Elsevier
Release Date : 1998-08-25
Cell Polarity written by J.R. Bartles and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-25 with Science categories.
Few cells conform to the stereotype of the spherical blob hastily scribbled on chalkboards and, regrettably, sometimes even displayed prominently in textbooks. Instead, real cells display a remarkable degree of structural and functional asymmetry. In modern cell biological parlance, this asymmetry has come to be lumped under the general heading of "cell polarity". Cell polarity is by no means restricted to the cells of tissues and organs, but can also be displayed by cells that lead a more solitary existence. The amazing extent to which cell morphology is correlated with function has long been a source of inspiration for biologists. Today the fascination continues unabated in the field of cell polarity, where it is fueled by an ever-deepening appreciation for the ways that fundamental cellular processes, such as membrane trafficking and cytoskeleton assembly, contribute to the establishment and maintenance of cell polarity. In the ensuing chapters, a collection of experts will summarize and interpret the findings obtained from basic research on cell polarity in a diverse array of experimental systems.
Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2004
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.
Amphibian Models Of Development And Disease
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Author : Sergei Y. Sokol
language : en
Publisher: Elsevier
Release Date : 2021-06-09
Amphibian Models Of Development And Disease written by Sergei Y. Sokol and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-09 with Science categories.
Intro -- Amphibian Models of Development and Disease -- Copyright -- Contents -- Contributors -- Preface -- Amphibian models: Pros and cons -- Looking ahead -- Acknowledgments -- Section I: From early development to morphogenesis and tissue patterning -- Chapter One: Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells -- 1. Introduction -- 2. MCC specification and differentiation -- 2.1. Notch signaling controls the balance of ciliated and secretory cell fates -- 2.2. Transcriptional regulation for MCC differentiation -- 2.2.1. Upstream regulation by geminin-like proteins -- 2.2.2. Downstream activators of MCC differentiation -- 3. Radial intercalation in the Xenopus epithelium -- 3.1. The role of cytoskeletal networks during radial intercalation -- 3.1.1. Actin cytoskeleton -- 3.1.2. Microtubule cytoskeleton -- 3.1.3. Coordination of actin and MT dynamics -- 3.2. Role of small GTPases during radial intercalation -- 3.2.1. RhoA -- 3.2.2. Other Rho GTPases (Rac/Cdc42) -- 3.2.3. Rab GTPases -- 3.3. Interactions with the surrounding microenvironment (cell-ECM/cell-cell interactions) -- 3.3.1. Cell-ECM interactions -- 3.3.2. Cell-cell interactions -- 4. Conclusions -- Acknowledgments -- References -- Chapter Two: Xenopus neural tube closure: A vertebrate model linking planar cell polarity to actomyosin contractions -- 1. Introduction -- 2. Mechanisms leading to PCP -- 2.1. Assembly of core PCP complexes -- 2.2. PCP cues -- 3. PCP and actomyosin contractility -- 3.1. Rho GTPases and Myosin II in actomyosin contractility and force generation -- 3.2. Linking PCP signaling to the Rho-ROCK-Myosin II pathway -- 4. The PCP pathway in neural tube closure -- 4.1. Cell behaviors and PCP protein localization in the neural plate -- 4.2. Cross-talk between PCP protein localization and actomyosin contractility.
Tight Junctions In Cancer Metastasis
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Author : Tracey A. Martin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-02-26
Tight Junctions In Cancer Metastasis written by Tracey A. Martin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-26 with Medical categories.
There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.
Heart Development And Regeneration
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Author : Nadia Rosenthal
language : en
Publisher: Academic Press
Release Date : 2010-05-28
Heart Development And Regeneration written by Nadia Rosenthal and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-28 with Science categories.
The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration. - Authored by world experts in heart development and disease - New research on epigenetic modifiers in cardiac development - Comprehensive coverage of stem cells and prospects for cardiac regeneration - Up-to-date research on transcriptional and proteomic circuits in cardiac disease - Full-color, detailed illustrations