Expanding The Cure Model
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Expanding The Cure Model
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Author : Rory Waterman
language : en
Publisher:
Release Date : 2018
Expanding The Cure Model written by Rory Waterman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Extending The Cure
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Author : Ramanan Laxminarayan
language : en
Publisher: Routledge
Release Date : 2010-09-30
Extending The Cure written by Ramanan Laxminarayan and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-30 with Medical categories.
Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.
Extending The Cure
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Author : Ramanan Professor Laxminarayan
language : en
Publisher: Routledge
Release Date : 2010-09-30
Extending The Cure written by Ramanan Professor Laxminarayan and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-30 with Medical categories.
Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.
The Expanded Red Hook Streetcar Project A Cure For Transportation Deserts
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Author : Bob Diamond
language : en
Publisher: Lulu.com
Release Date :
The Expanded Red Hook Streetcar Project A Cure For Transportation Deserts written by Bob Diamond and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Cure Models
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Author : Yingwei Peng
language : en
Publisher: CRC Press
Release Date : 2021-03-22
Cure Models written by Yingwei Peng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-22 with Mathematics categories.
Cure Models: Methods, Applications and Implementation is the first book in the last 25 years that provides a comprehensive and systematic introduction to the basics of modern cure models, including estimation, inference, and software. This book is useful for statistical researchers and graduate students, and practitioners in other disciplines to have a thorough review of modern cure model methodology and to seek appropriate cure models in applications. The prerequisites of this book include some basic knowledge of statistical modeling, survival models, and R and SAS for data analysis. The book features real-world examples from clinical trials and population-based studies and a detailed introduction to R packages, SAS macros, and WinBUGS programs to fit some cure models. The main topics covered include the foundation of statistical estimation and inference of cure models for independent and right-censored survival data, cure modeling for multivariate, recurrent-event, and competing-risks survival data, and joint modeling with longitudinal data, statistical testing for the existence and difference of cure rates and sufficient follow-up, new developments in Bayesian cure models, applications of cure models in public health research and clinical trials.
Exploring Novel Approaches To Eliminate Hiv Reservoirs To Achieve A Cure For Hiv
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Author : Renee Marije Van Der Sluis
language : en
Publisher: Frontiers Media SA
Release Date : 2021-04-07
Exploring Novel Approaches To Eliminate Hiv Reservoirs To Achieve A Cure For Hiv written by Renee Marije Van Der Sluis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-07 with Science categories.
Healthcare S Out Sick Predicting A Cure Solutions That Work
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Author : Gary D. Miner
language : en
Publisher: CRC Press
Release Date : 2019-01-04
Healthcare S Out Sick Predicting A Cure Solutions That Work written by Gary D. Miner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-04 with Medical categories.
The U.S. healthcare system is in "complete chaos-disarray." Medical costs have increased significantly over the past 6 years with 70% increase for deductibles and 24% or more for health insurance premiums. All the while, workers earnings have either not increased or if they did, the pay raises were for less than the increase in the cost of medical care. The situation is unsustainable and the public wants the system fixed. This book offers ways of fixing the problems in healthcare. HEALTHCARE's OUT SICK - PREDICTING A CURE - Solutions that WORK !!!! first defines the "healthcare in crisis" problem. Through real patient experiences, the book describes the difficulties of getting through the maze of complexity among the plethora of "silo providers" which make up the industry. The heart of the book provides readers with a comprehensive solution that can work, a disruption that is necessary to provide Americans the medical care they need without the US public and healthcare providers and payors going into bankruptcy, insolvency or closure. This book delves into digitized medicine, payor and provider reimbursement models, and value-based healthcare delivery. It also includes a philosophy or mode of thinking and operation for the solutions that are needed for diagnosis-effective, cost-effective, and time-efficient healthcare delivery, of which digitized medicine, value-based care, and payor reimbursement modes are just some of the factors. The authors propose that the real solution involves having the patient at the center of the issues and changing from an archaic gold standard way of thinking to a "Predictive Analytic thinking" where one gets at the real truth by doing "real science" that in the end becomes effective not only for the population but for the individual person. This all leads to real person-centered and person-directed medicine and healthcare delivery.
Lymph Node T Cell Dynamics And Novel Strategies For Hiv Cure
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Author : Constantinos Petrovas
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-11
Lymph Node T Cell Dynamics And Novel Strategies For Hiv Cure written by Constantinos Petrovas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-11 with categories.
Currently, more than 36 million people are infected with HIV. Although the introduction of highly active anti-retroviral therapy (HAART) has led to substantial advances in the clinical management of HIV infected individuals, HAART cannot completely eliminate the virus. This is because CD4 T helper cells, harboring the virus, remain dormant reservoirs. These reservoirs are difficult to measure and are present even in HAART-treated HIV infected individuals with undetectable levels of HIV in the blood. A growing body of studies has revealed follicular helper (Tfh) CD4 T cells, a highly differentiated CD4 T cell population localized in immunologically sanctuary sites (follicle/germinal center), as a major reservoir of HIV. The present Frontiers in Immunology eBook compiles 16 timely review articles focusing on the dynamics of major follicular immune cell types in HIV/SIV infection and their potential role for disease pathogenesis and the viral persistence in the lymph node. This eBook provides a comprehensive presentation of recent published work on lymph node and especially Tfh cell dynamics in HIV infection and we hope that it will be useful for our further understanding of how such dynamics affect the interplay between virus and host as well as for the discovery of novel therapeutic targets in the fight against HIV.
Rapid Cure Composites
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Author : Nishar Hameed
language : en
Publisher: Elsevier
Release Date : 2023-05-17
Rapid Cure Composites written by Nishar Hameed and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-17 with Technology & Engineering categories.
Rapid Cure Composites: Materials, Processing and Manufacturing presents up-to-date information on the design criteria to formulate matrix systems for rapid curing. Emphasis is placed on the role different materials [resin compound and fiber reinforcement] play in developing fast curing composites, assessment of current and novel manufacturing techniques for adapting fast curing processes, the comparison between conventional curing and rapid curing, and different applications in various industrial sectors [e.g., aerospace, automotive, renewables and marine]. The book will be an essential reference resource for academic and industrial researchers working in the field of composite materials, processing and manufacturing organizations, materials scientists, and more. Polymer composites are widely used in several industries, including aerospace, automobile, spray and coatings, and electronics due to their lightweight and superior mechanical properties. However, one of the dominant hurdles towards their growth in commercial industries is the long curing cycle and slow production. Comprehensively addresses the scientific and technological development of rapid cured epoxy composites Covers, in detail, the chemistry, processing, structure and performance of rapid cured epoxy composites Provides detailed comparisons of how/why rapid cure composites are different to conventional composites Discusses the challenges of the existing technology and future trends
Joint Modeling Of Longitudinal And Time To Event Data
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Author : Robert Elashoff
language : en
Publisher: CRC Press
Release Date : 2016-10-04
Joint Modeling Of Longitudinal And Time To Event Data written by Robert Elashoff and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-04 with Mathematics categories.
Longitudinal studies often incur several problems that challenge standard statistical methods for data analysis. These problems include non-ignorable missing data in longitudinal measurements of one or more response variables, informative observation times of longitudinal data, and survival analysis with intermittently measured time-dependent covariates that are subject to measurement error and/or substantial biological variation. Joint modeling of longitudinal and time-to-event data has emerged as a novel approach to handle these issues. Joint Modeling of Longitudinal and Time-to-Event Data provides a systematic introduction and review of state-of-the-art statistical methodology in this active research field. The methods are illustrated by real data examples from a wide range of clinical research topics. A collection of data sets and software for practical implementation of the joint modeling methodologies are available through the book website. This book serves as a reference book for scientific investigators who need to analyze longitudinal and/or survival data, as well as researchers developing methodology in this field. It may also be used as a textbook for a graduate level course in biostatistics or statistics.