From Experimental Network To Meta Analysis

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From Experimental Network To Meta Analysis

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Author : David Makowski
language : en
Publisher: Springer
Release Date : 2019-05-07

From Experimental Network To Meta Analysis written by David Makowski and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-07 with Technology & Engineering categories.

This book has been designed as a methodological guide and shows the interests and limitations of different statistical methods to analyze data from experimental networks and to perform meta-analyses. It is intended for engineers, students and researchers involved in data analysis in agronomy and environmental science.

Machine Learning And Knowledge Discovery In Databases

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Author : José L. Balcázar
language : en
Publisher: Springer
Release Date : 2010-08-18

Machine Learning And Knowledge Discovery In Databases written by José L. Balcázar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-18 with Computers categories.

Annotation. This book constitutes the refereed proceedings of the joint conference on Machine Learning and Knowledge Discovery in Databases: ECML PKDD 2010, held in Barcelona, Spain, in September 2010. The 120 revised full papers presented in three volumes, together with 12 demos (out of 24 submitted demos), were carefully reviewed and selected from 658 paper submissions. In addition, 7 ML and 7 DM papers were distinguished by the program chairs on the basis of their exceptional scientific quality and high impact on the field. The conference intends to provide an international forum for the discussion of the latest high quality research results in all areas related to machine learning and knowledge discovery in databases. A topic widely explored from both ML and DM perspectives was graphs, with motivations ranging from molecular chemistry to social networks.

Data Management Of Protein Interaction Networks

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Author : Mario Cannataro
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-03

Data Management Of Protein Interaction Networks written by Mario Cannataro and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-03 with Computers categories.

Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed.

Multimodality Therapy For Older Cancer Patients

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Author : Nam Phong Nguyen
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-01

Multimodality Therapy For Older Cancer Patients written by Nam Phong Nguyen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-01 with Medical categories.

Older cancer patients are frequently excluded from clinical trials due to the concern about toxicity. Chronologically older cancer patients may not receive curative treatment especially when it involves multi-modality such as surgery and radiotherapy or chemotherapy and radiotherapy even when they are physically fit. As there is a paucity of data on older cancer patients, clinicians are often faced with a difficult choice on how to manage those patients who have many co-morbidities. As an international research organization dedicated to the care of older cancer patients, minorities, and women, the International Geriatric Radiotherapy Group would like to investigate the pattern of care across the world on the specific topic of multi-modality treatment for older cancer patients. The primary goal of our Research Topic is to assess older cancer patients' tolerance to a multimodality approach for cure or for palliation in light of new modality treatments such as targeted agents or immunotherapy which may improve outcome and toxicity in selected patients. The underlying molecular biology rationale for such an approach may also lead to new paradigms to improve the quality of care. The secondary goal of the collection is to assess treatment outcomes such as survival, disease-free survival, and loco-regional control of older cancer patients compared to younger ones.

Knowledge Translation In Health Care

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Author : Sharon E. Straus
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24

Knowledge Translation In Health Care written by Sharon E. Straus and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Medical categories.

Health care systems worldwide are faced with the challenge of improving the quality of care. Providing evidence from health research is necessary but not sufficient for the provision of optimal care and so knowledge translation (KT), the scientific study of methods for closing the knowledge-to-action gap and of the barriers and facilitators inherent in the process, is gaining significance. Knowledge Translation in Health Care explains how to use research findings to improve health care in real life, everyday situations. The authors define and describe knowledge translation, and outline strategies for successful knowledge translation in practice and policy making. The book is full of examples of how knowledge translation models work in closing the gap between evidence and action. Written by a team of authors closely involved in the development of knowledge translation this unique book aims to extend understanding and implementation worldwide. It is an introductory guide to an emerging hot topic in evidence-based care and essential for health policy makers, researchers, managers, clinicians and trainees.

Human Motor Development

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Author : V. Gregory Payne
language : en
Publisher: Taylor & Francis
Release Date : 2024-08-13

Human Motor Development written by V. Gregory Payne and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-13 with Medical categories.

Human Motor Development: A Lifespan Approach, Eleventh Edition provides an overview of the academic field of study known as human motor development, the examination of lifelong changes in human movement. The book uses a holistic approach and emphasizes the importance of intellectual, social, and physical development and their impact on human motor development at all ages. The unique approach of this book includes the relationships between motor development and critical interactions with cognitive, social, and physical changes across the lifespan. Organized into five parts, the book examines key topics in motor development, including the relationship between cognitive and social development and motor development, factors affecting development, changes across the lifespan, and assessment in motor development, with special attention being applied to adulthood and older adulthood, given the increasing numbers of people in those age groups worldwide. Each chapter includes chapter objectives, a summary, a list of key concepts, questions for reflection, a list of related online resources, and an extensive reference list. Highly illustrated and written for student accessibility by providing access to a fully updated companion website, which includes laboratory exercises, an instructors’ manual, a test bank, and lecture slides, Human Motor Development: A Lifespan Approach is essential reading for students of motor control and development, kinesiology, and human performance and for students interested in physical therapy, physical education, and exercise science.

Complementary And Alternative Therapies For Sleep Disorders From Bench To Bedside

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Author : Guanhu Yang
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-12

Complementary And Alternative Therapies For Sleep Disorders From Bench To Bedside written by Guanhu Yang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-12 with Medical categories.

Sleep disorders encompass a range of conditions that can significantly impact overall health, safety, and quality of life. Symptoms of sleep disorders include excessive daytime sleepiness, irregular breathing or movements during sleep, disrupted sleep, and difficulty falling asleep. If these conditions are not promptly and effectively treated, patients often experience various physical and mental complications, such as psychiatric disorders, cardiovascular disease, stroke, type 2 diabetes, and obesity, leading to a decreased overall quality of life. Complementary and alternative therapy (CAT) presents a potential approach for the prevention and treatment of sleep disorders. It encompasses a range of management practices, including cognitive behavioral therapy, exercise, mindfulness, meditation, transcranial magnetic stimulation, yoga, herbal medicine, acupuncture, acupressure, Gua Sha, moxibustion, Qigong, Tai Chi, acupoint catgut embedding, acupotomy, nutritional supplements, and vitamin supplements. However, the adoption of CAT for sleep disorders in clinical practice faces numerous challenges due to a limited understanding of their mechanisms and clinical effects.

Quantitative Assessment And Validation Of Network Inference Methods In Bioinformatics

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Author : Benjamin Haibe-Kains
language : en
Publisher: Frontiers Media SA
Release Date : 2015-04-14

Quantitative Assessment And Validation Of Network Inference Methods In Bioinformatics written by Benjamin Haibe-Kains and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-14 with Bioengineering categories.

Scientists today have access to an unprecedented arsenal of high-tech tools that can be used to thoroughly characterize biological systems of interest. High-throughput “omics” technologies enable to generate enormous quantities of data at the DNA, RNA, epigenetic and proteomic levels. One of the major challenges of the post-genomic era is to extract functional information by integrating such heterogeneous high-throughput genomic data. This is not a trivial task as we are increasingly coming to understand that it is not individual genes, but rather biological pathways and networks that drive an organism’s response to environmental factors and the development of its particular phenotype. In order to fully understand the way in which these networks interact (or fail to do so) in specific states (disease for instance), we must learn both, the structure of the underlying networks and the rules that govern their behavior. In recent years there has been an increasing interest in methods that aim to infer biological networks. These methods enable the opportunity for better understanding the interactions between genomic features and the overall structure and behavior of the underlying networks. So far, such network models have been mainly used to identify and validate new interactions between genes of interest. But ultimately, one could use these networks to predict large-scale effects of perturbations, such as treatment by multiple targeted drugs. However, currently, we are still at an early stage of comprehending methods and approaches providing a robust statistical framework to quantitatively assess the quality of network inference and its predictive potential. The scope of this Research Topic in Bioinformatics and Computational Biology aims at addressing these issues by investigating the various, complementary approaches to quantify the quality of network models. These “validation” techniques could focus on assessing quality of specific interactions, global and local structures, and predictive ability of network models. These methods could rely exclusively on in silico evaluation procedures or they could be coupled with novel experimental designs to generate the biological data necessary to properly validate inferred networks.

Encyclopedia Of Bioinformatics And Computational Biology

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Author :
language : en
Publisher: Elsevier
Release Date : 2018-08-21

Encyclopedia Of Bioinformatics And Computational Biology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-21 with Medical categories.

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Understanding The Complex Phenomenon Of Suicide From Research To Clinical Practice

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Author : Domenico De Berardis
language : en
Publisher: Frontiers Media SA
Release Date : 2018-05-08

Understanding The Complex Phenomenon Of Suicide From Research To Clinical Practice written by Domenico De Berardis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-08 with categories.

Suicide is undoubtedly a worldwide major challenge for the public health. It is estimated that more than 150,000 persons in Europe die as a result of suicide every year and in several European countries suicide represents the principal cause of death among young people aged 14–25 years. It is true that suicide is a complex (and yet not fully understood) phenomenon and may be determined by the interaction between various factors, such as neurobiology, personal and familiar history, stressful events, sociocultural environment, etc. The suicide is always a plague for the population at risk and one of the most disgraceful events for a human being. Moreover, it implies a lot of pain often shared by the relatives and persons who are close to suicide subjects. Furthermore, it has been widely demonstrated that the loss of a subject due to suicide may be one of the most distressing events that may occur in mental health professionals resulting in several negative consequences, such as burnout, development of psychiatric symptoms and lower quality of life and work productivity. All considered, it is clear that the suicide prevention is a worldwide priority and every effort should be made in order to improve the early recognition of imminent suicide, manage suicidal subjects, and strengthen suicide prevention strategies. In our opinion, the first step of prevention is the improvement of knowledge in the field: this was the aim of this present special issue on Frontiers in Psychiatry. In this special issue, several papers have contributed to the suicide knowledge from several viewpoints and we hope that this will contribute to improve and disseminate knowledge on this topic.