Frontiers In The Pharmacological Manipulation Of Intracellular Camp Levels
DOWNLOAD
Download Frontiers In The Pharmacological Manipulation Of Intracellular Camp Levels PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Frontiers In The Pharmacological Manipulation Of Intracellular Camp Levels book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Frontiers In The Pharmacological Manipulation Of Intracellular Camp Levels
DOWNLOAD
Author : George S. Baillie
language : en
Publisher: Frontiers Media SA
Release Date : 2016-04-08
Frontiers In The Pharmacological Manipulation Of Intracellular Camp Levels written by George S. Baillie and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-08 with Electronic book categories.
Cyclic adenosine monophosphate (cAMP) is a second messenger of paramount biological importance, involved in the regulation of a significant number of cellular functions through the cAMP-dependent intracellular signal transduction pathways. The aim of this "Frontiers in Pharmacology" Research Topic was to attract contributions that highlight emerging ideas in the cAMP field that: (i) describe its role in cellular function and homeostasis, (ii) present the current approaches to its pharmacological manipulation, and (iii) clarify its central role in the development of more targeted therapeutic approaches toward a spectrum of diseases. The present collection of articles highlights, in a representative (but certainly not exhaustive) way, the research activity and emerging concepts in the field, while it also reveals the therapeutic potential that targeted pharmacological manipulation of intracellular cAMP levels could exert on a number of pathological conditions.
Frontiers In The Pharmacological Manipulation Of Intracellular Camp Levels
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2016
Frontiers In The Pharmacological Manipulation Of Intracellular Camp Levels written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Cyclic adenosine monophosphate (cAMP) is a second messenger of paramount biological importance, involved in the regulation of a significant number of cellular functions through the cAMP-dependent intracellular signal transduction pathways. The aim of this "Frontiers in Pharmacology" Research Topic was to attract contributions that highlight emerging ideas in the cAMP field that: (i) describe its role in cellular function and homeostasis, (ii) present the current approaches to its pharmacological manipulation, and (iii) clarify its central role in the development of more targeted therapeutic approaches toward a spectrum of diseases. The present collection of articles highlights, in a representative (but certainly not exhaustive) way, the research activity and emerging concepts in the field, while it also reveals the therapeutic potential that targeted pharmacological manipulation of intracellular cAMP levels could exert on a number of pathological conditions.
Survival In Extreme Environments Adaptation Or Decompensation Volume I
DOWNLOAD
Author : Torkjel Tveita
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-28
Survival In Extreme Environments Adaptation Or Decompensation Volume I written by Torkjel Tveita and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-28 with Science categories.
Frontiers In Clinical Drug Research Alzheimer Disorders
DOWNLOAD
Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2018-11-02
Frontiers In Clinical Drug Research Alzheimer Disorders written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Science categories.
Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD), a disease that causes dementia, or loss of brain function. This disease affects parts of the brain that affect memory, thought, and language. Chapters in each volume focus on drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.
Myelin Mediated Inhibition Of Axonal Regeneration Past Present And Future
DOWNLOAD
Author : Sari Hannila
language : en
Publisher: Frontiers Media SA
Release Date : 2017-07-06
Myelin Mediated Inhibition Of Axonal Regeneration Past Present And Future written by Sari Hannila and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with Electronic book categories.
Pioneering studies conducted in the 1980’s laid the foundation for the hypothesis that axonal regeneration is limited by CNS myelin, and the identification of myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte myelin glycoprotein (OMgp) as inhibitors of neurite outgrowth firmly established myelin as a key factor in regenerative failure. Mechanistically, it has been shown that MAG, Nogo, and OMgp mediate inhibition by binding to either Nogo receptor (NgR) or paired immunoglobulin receptor B (PirB), and initiating a signaling cascade that culminates in the activation of RhoA. Since the discovery of these proteins, there has been tremendous interest in identifying compounds and molecular mechanisms that are capable of overcoming myelin-mediated inhibition. Many studies have focused on pharmacological antagonism of receptors and signaling intermediates, while others have sought to identify and enhance endogenous pro-regenerative pathways. The most notable example of the latter is the conditioning lesion effect, which led to the discovery of cyclic AMP’s ability to overcome inhibition by MAG and myelin. Many of the agents tested in these studies have been shown to promote axonal regeneration in vivo, and this research topic allows researchers to share information about new treatments that have been developed in both academia and industry. As we look toward the future, it is becoming increasingly clear that reversal of myelin-mediated inhibition alone will not be sufficient to produce functional recovery from spinal cord injury, and that other factors, such as astroglial scarring, the expression of chondroitin sulfate proteoglycans, neuronal cell death, and lack of neurotrophic support, must also be taken into consideration. Combinatorial approaches therefore hold a great deal of promise, and we hope to initiate a dialogue on how stem cell transplantation, chondroitinase ABC, gene therapy, growth-promoting agents, and other methods can be combined to optimize functional recovery. We introduce this topic in honor of the life and work of Dr. Marie T. Filbin (1955-2014). Through these articles, we highlight past achievements in the field, novel findings, unanswered questions and innovative ideas that we hope will lead to new advances in axonal regeneration.
Purinergic Pharmacology
DOWNLOAD
Author : Francisco Ciruela
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-16
Purinergic Pharmacology written by Francisco Ciruela and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-16 with categories.
The Endocannabinoid System Filling The Translational Gap Between Neuroscience And Psychiatry
DOWNLOAD
Author : Marco Colizzi
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-24
The Endocannabinoid System Filling The Translational Gap Between Neuroscience And Psychiatry written by Marco Colizzi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Medical categories.
Adenylyl Cyclase Isoforms As Potential Drug Targets
DOWNLOAD
Author : Tarsis Brust
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-09
Adenylyl Cyclase Isoforms As Potential Drug Targets written by Tarsis Brust and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-09 with Science categories.
Insights In Gastrointestinal And Hepatic Pharmacology 2021
DOWNLOAD
Author : Angelo A. Izzo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-05
Insights In Gastrointestinal And Hepatic Pharmacology 2021 written by Angelo A. Izzo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-05 with Science categories.
Endocrine Frailty In The Elderly
DOWNLOAD
Author : Sandro La Vignera
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-04
Endocrine Frailty In The Elderly written by Sandro La Vignera and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-04 with categories.