Function And Regulation Of Chemoreceptors

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Function And Regulation Of Chemoreceptors

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Author : Dieter Wicher
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-08

Function And Regulation Of Chemoreceptors written by Dieter Wicher and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-08 with categories.

To perceive environmental chemical compounds and to convert these external signals into an intracellular message might be the oldest way for a living being to get information from the outside world. Chemoreceptors are proteins or protein complexes that detect molecules from the outside world either at distance (olfaction) or at close range (gustation). Chemoreceptors can operate as ionotropic or as metabotropic receptors. Ionotropic receptors form ion channels that are activated via ligand binding. Activation of a metabotropic receptor initiates an intracellular signaling cascade that could include a change of enzymatic activity, production of second messenger or activation of ion channels. The receptor performance has to be fine-tuned according to the actual physiological requirements and the presentation of the chemical signal. This Research Topic collects reports and reviews on structure and function of chemoreceptors in the animal kingdom, and how these receptors are regulated.

Neuromodulatory Control Of Brainstem Function In Health And Disease

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Author : Brian R. Noga
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-25

Neuromodulatory Control Of Brainstem Function In Health And Disease written by Brian R. Noga and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-25 with categories.

Airway Chemoreceptors In Vertebrates

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Author : Giacomo Zaccone
language : en
Publisher: CRC Press
Release Date : 2019-04-23

Airway Chemoreceptors In Vertebrates written by Giacomo Zaccone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-23 with Science categories.

The book provides a comprehensive and up-to-date account of the information available on the morphological, physiological and evolutionary aspects of specialized cells distributed within the epithelia of the airways in the vertebrates. A lot of work has been done on the cell and molecular biology of these cells which are regarded as as oxygen recep

Essentials Of Pathophysiology

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Author : Carol Porth
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2011

Essentials Of Pathophysiology written by Carol Porth and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.

Porth Pathophysiology: understanding made easy, delivered however you need it. Porth's "Essentials of Pathophysiology" 3e delivers exceptional student understanding and comprehension of pathophysiology. An expanded, robust and flexible suite of supplements makes it easy for you to select the best course resources, so you can meet your students' changing needs. For both discrete and hybrid courses, the flexibility and power of Porth allows you to customize the amount of pathophysiology that you need for effective teaching and learning. Including a resource DVD with text!

The Role Of Mixed Venous Chemoreceptors In The Reflex Regulation Of Cardiac Output In The Sheep

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Author : Nitin Bhalchandra Kulkarni
language : en
Publisher:
Release Date : 1994

The Role Of Mixed Venous Chemoreceptors In The Reflex Regulation Of Cardiac Output In The Sheep written by Nitin Bhalchandra Kulkarni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.

Ph And Brain Function

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Author : Kai Kaila
language : en
Publisher: John Wiley & Sons
Release Date : 1998-09-15

Ph And Brain Function written by Kai Kaila and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-09-15 with Medical categories.

"PH and Brain Function offers thorough coverage of this increasingly important area of research, beginning with the fundamental concepts, which include methodological and theoretical issues such as the measurement of pH and the concept of pH in neurobiology. It explores aspects of regulation and modulation of intracellular pH in brain cells, surveys the changes in pH that occur with neural activity and how these changes affect neural activity, and discusses the role of pH in the pathophysiology of neurological diseases." "pH and Brain Function is an important resource for researchers in all areas of neuroscience as well as cell biology and physiology." --Book Jacket.

Hypertensive Crisis Pathophysiology Management And Prognosis

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Author : Dr. Spineanu Eugenia
language : en
Publisher: Dr. Spineanu Eugenia
Release Date : 2025-02-19

Hypertensive Crisis Pathophysiology Management And Prognosis written by Dr. Spineanu Eugenia and has been published by Dr. Spineanu Eugenia this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-19 with Medical categories.

Explore "Hypertensive Crisis: Pathophysiology, Management, and Prognosis," a comprehensive guide revealing insights into the intricate mechanisms, urgent management strategies, and long-term prognosis of hypertensive emergencies and urgencies. Delve into the complexities of blood pressure regulation, from neurohormonal pathways to acute end-organ damage. Discover evidence-based approaches to immediate intervention, including pharmacological treatments and non-pharmacological measures like mechanical ventilation. Gain invaluable perspectives on chronic complications affecting vital organs and cognitive functions. This treatise illuminates the latest advancements in therapeutic innovations and public health strategies aimed at reducing the global burden of hypertensive crises. Essential reading for healthcare professionals and researchers dedicated to optimizing patient outcomes and enhancing cardiovascular health worldwide.

Arterial Chemoreceptors

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Author : Constancio Gonzalez
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-21

Arterial Chemoreceptors written by Constancio Gonzalez and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-21 with Medical categories.

This book offers an updated review of the physiology of the carotid body chemoreceptors. It provides the trends in the field as it contains results in the topics that are at the frontiers of future developments in O2-sensing in chemoreceptor cells.

Carotid Body A New Target For Rescuing Neural Control Of Cardiorespiratory Balance In Disease

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Author : Rodrigo Del Rio
language : en
Publisher: Frontiers Media SA
Release Date : 2016-12-12

Carotid Body A New Target For Rescuing Neural Control Of Cardiorespiratory Balance In Disease written by Rodrigo Del Rio and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-12 with Physiology categories.

The carotid body (CB) is in charge of adjusting ventilatory and cardiovascular function during changes in arterial blood gases. Regardless this essential function, the CB has been implicated in the sensing of other physiological signals such as changes in blood flow and glucose levels. More important, malfunction of the CB chemoreceptors has been associated with the progression and deterioration of several disease states such as hypertension, heart failure, renal failure, insulin resistance, diabetes and sleep apnea. Although the mechanisms involved in the alterations of the CB function in pathophysiology are currently under intense research, the development of therapeutic approaches to restore normal CB chemoreflex function remains unsolved. Recent studies showing the effect of CB denervation in pathophysiology have unveiled a key role of these arterial chemoreceptors in the development of autonomic imbalance and respiratory disturbances, and suggest that targeting the CB could represent a novel strategy to improve disease outcome. Unfortunately, classical pharmacotherapy intended to normalize CB function may be hard to establish since several cellular pathways are involved in the CB dysfunction. Augmented levels of angiotensin II, endothelin-1, cytokines and free radicals along with decreases in nitric oxide had all been related to the CB dysfunction. Moreover, changes in expression of angiotensin receptors, nitric oxide synthases and cytokines that take place within the CB tissue in pathological states also contribute to the enhanced CB chemoreflex drive. It has been shown in heart failure, hypertension and obstructive sleep apnea that the CB becomes tonically hyper-reactive. During the progression of the disease this CB chemosensory facilitation process induces central nervous system plasticity. The altered autonomic-respiratory control leads to increased cardiorespiratory distress and the deterioration of the condition. The focus of this e-book will be to cover the role of the CB in pathophysiology and to provide new evidence of the pathways involved in the maladaptive potentiation of the CB chemoreflex function. In memory of Professor Mashiko Shirahata and Professor Constancio Gonzalez.

Subject Index Of Current Research Grants And Contracts Administered By The National Heart And Lung Institute

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Author : National Heart and Lung Institute
language : en
Publisher:
Release Date : 1975

Subject Index Of Current Research Grants And Contracts Administered By The National Heart And Lung Institute written by National Heart and Lung Institute and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Cardiology categories.