Gastrointestinal Tumorigenesis
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Advances In The Molecular Mechanisms In Gastrointestinal Tumorigenesis And Treatment
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Author : Ruowen Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-16
Advances In The Molecular Mechanisms In Gastrointestinal Tumorigenesis And Treatment written by Ruowen Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-16 with Medical categories.
Intestinal Tumorigenesis
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Author : Vincent W. Yang
language : en
Publisher: Springer
Release Date : 2015-09-19
Intestinal Tumorigenesis written by Vincent W. Yang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-19 with Medical categories.
This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tumorigenesis lead to further understanding of mechanisms involved in colon cancer. Additionally, advancements in techniques and methods open the doors for new approaches to better define the molecular and organismal mechanisms of intestinal tumorigenesis. Chapters are authored by widely published authorities in the field. Each year, there are close to 150,000 new cases of colorectal cancer, which results in approximately 50,000 deaths per year in the United States; these figures render colorectal cancer a significant health concern. Studies attempting to understand the mechanisms of development and progression of colorectal cancer have been ongoing for decades and each year brings new discoveries yielding a better comprehension of the underlying processes at work.
Gastrointestinal Tumorigenesis
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Author : Maesha Deheragoda
language : en
Publisher: World Scientific Publishing Company
Release Date : 2011
Gastrointestinal Tumorigenesis written by Maesha Deheragoda and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
This book explains tumorigenic mechanisms underlying common cancers from different sites of the gut, using illustrations of important mechanisms and pathways. There is emphasis on the importance of stem cells and the spread of mutations during tumorigenesis. Photographs will be used to enable pathologists and other clinicians to relate histological appearances to underlying tumorigenic processes, thereby putting these appearances into context. The volume considers how current management regimes affect tumorigenesis and how an understanding of underlying mechanisms can lead to the development of new strategies for screening, diagnosis and therapy.
Disease Progression And Carcinogenesis In The Gastrointestinal Tract
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Author : P.R. Galle
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-09-30
Disease Progression And Carcinogenesis In The Gastrointestinal Tract written by P.R. Galle and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-30 with Medical categories.
Development and progression of gastrointestinal disease involves inflammatory, vascular, fibrogenetic and immune reactions accompanied by deregulation of cellular growth and death often resulting in cancer of the organs affected. This book, the proceedings of Falk Symposium 132 on `Disease Progression and Carcinogenesis in the Gastrointestinal Tract', held in Freiburg, Germany, October 9-10, 2002, addresses these various cellular processes in five sections in order to build up a broad pathogenic concept of gastrointestinal disease, purposely going beyond organ-specific research. Each section combines experts in the various fields of molecular medicine together with clinical scientists in order to stimulate interdisciplinary discussion. In addition, clinical chapters focus on new findings in both diagnostics and therapeutics.
Intestinal Tumorigenesis
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Author : Vincent W. Yang
language : en
Publisher:
Release Date : 2015
Intestinal Tumorigenesis written by Vincent W. Yang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tumorigenesis lead to further understanding of mechanisms involved in colon cancer. Additionally, advancements in techniques and methods open the doors for new approaches to better define the molecular and organismal mechanisms of intestinal tumorigenesis. Chapters are authored by widely published authorities in the field. Each year, there are close to 150,000 new cases of colorectal cancer, which results in approximately 50,000 deaths per year in the United States; these figures render colorectal cancer a significant health concern. Studies attempting to understand the mechanisms of development and progression of colorectal cancer have been ongoing for decades and each year brings new discoveries yielding a better comprehension of the underlying processes at work.
Gastrointestinal Cancer
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Author : William Robert Bruce
language : en
Publisher:
Release Date : 1981
Gastrointestinal Cancer written by William Robert Bruce and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Breast categories.
Inflammation Infection And Microbiome In Cancers
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Author : Jun Sun
language : en
Publisher: Springer Nature
Release Date : 2021-04-20
Inflammation Infection And Microbiome In Cancers written by Jun Sun and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-20 with Medical categories.
This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
Therapeutic Targets For Inflammation And Cancer Novel Therapies For Digestive Diseases
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Author : Cho Chi-hin
language : en
Publisher: World Scientific
Release Date : 2017-04-20
Therapeutic Targets For Inflammation And Cancer Novel Therapies For Digestive Diseases written by Cho Chi-hin and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-20 with Medical categories.
This unique book deals with both inflammation and cancer in a single source of publication. They are seldom grouped together although it has been known that both diseases are closely associated, particularly in the gastrointestinal tract and liver. As the book touches on two such major areas of diseases in humans, it should be of interest to a wider audience of researchers and readers. It is noted that the book combines the effort of both basic scientists and clinicians from different countries with extensive experiences in molecular biology and clinical practice to unveil the most updated picture of the pathogenesis and therapeutic strategies in the treatment of inflammation and cancer in the digestive tract. In this regard, potential pathogenic modulators and also therapeutic options are widely discussed. These types of information would definitely broaden our knowledge in better understanding these diseases. Contents:General Introduction to Inflammation and Cancer in the Digestive Tract (Ming Xing Li and Chi Hin Cho)Inflammation and Therapeutics in the Digestive Tract:Brain–Gut Relationship on Mucosal Inflammation in the Gastrointestinal Tract (Klara Gyires and Ágnes Fehér)Nesfatin-1: The Novel Appetite Peptide with Therapeutic Efficacy to Prevent Acute Hemorrhagic Gastric Lesions and Accelerate Gastric Ulcer Healing (Aleksandra Szlachcic, Jolanta Majka, and Tomasz Brzozowski)Chemoprophylaxis in Inflammatory Bowel Disease (Nikola Mitrev, Aladdin Alswaifi, and Rupert W Leong)Targeting the Nuclear Receptor HNF4α as a Potential Therapy for Gut Inflammation and Cancer (Jean-Philippe Babeu and François Boudreau)Established Therapies and New Therapeutic Strategies in Alcoholic Liver Disease (Helmut Karl Seitz and Sebastian Mueller)Carcinogenesis and Therapeutic Targets in the Gastrointestinal Tract:Targets of Tumor Epigenetics and Its Microenvironment in Gastrointestinal Cancer (Ssu-Yin Yen, Hong-Meng Chuang, Mao-Hsuan Huang, Sheng-Feng Tsai, Tzyy-Wen Chiou, Hong-Lin Su, Li-Ing Ho, Shinn-Zong Lin, and Horng-Jyh Harn)Esophageal Cancer: From Bench to Bedside (Gang Ma and Zhihua Liu)Angiogenesis and Lymphangiogenesis in Gastric MALT Lymphoma: Relation of VEGF and VASH2 (Masahiko Nakamura, Anders Øverby, and Hidenori Matsui)NF-κB as a Potential Molecular Target for Therapy of Gastrointestinal Cancers (Nathan Palmer, Muthu K Shanmugam, Gautam Sethi, and Philipp Kaldis)Hypoxia-Inducible Factor-1κ Modulation in Colorectal Carcinogenesis (Francesco Mariani, Stefano Mancini, Paola Sena, and Luca Roncucci)Therapeutic Approaches Targeting the Serrated Pathway of Colorectal Cancer Characterized by Mutation in the BRAF Gene and Overexpression of GTPase Rac1b (Paulo Matos, Vânia Gonçalves, and Peter Jordan)The "Yin" and "Yang" of Target-Oriented Anticancer Phytochemicals Derived from Herbal Medicines (Kathy K Auyeung and Joshua K S Ko)The Degradation System of Prostaglandin E2 in Gastrointestinal Cancer (Tetsuya Tanigawa, Toshio Watanabe, Shogo Takeda, Hiroshi Tatsuwaki, Masatsugu Shiba, Kazunari Tominaga, Yasuhiro Fujiwara, and Tetsuo Arakawa)Prostaglandin and Its Receptors: Potential Targets for Gastrointestinal Inflammation and Cancer (Vivian Y Shin and Ava Kwong)Autophagy and microRNAs as the Therapeutic Targets in Gastrointestinal Cancers:Modulation of Autophagy as a Potential Therapeutic Target for Gastrointestinal Cancers: Promises and Uncertainties (Li Ma)microRNAs as Therapeutic Targets for Gastric Cancer (Takatsugu Ishimoto and Hideo Baba)microRNA-based Novel Therapeutic Development in Gastrointestinal Cancer (Andrew Fesler and Jingfang Ju)Unraveling the Relationship between Autophagy and microRNA in Gastrointestinal Cancer (Yuanyuan Yin, Peiqi Wang, Yaxin Zheng, Yi Chen, and Jinhui Wang) Readership: Basic and clinical researchers in the fields of inflammation, hepatology, pathology, pharmacology, oncology and gastroenterology. Can be used as a reference for their research and clinical practice in academic and industrial sectors.
Antimicrobial Peptides In Gastrointestinal Diseases
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Author : Chi Hin Cho
language : en
Publisher: Academic Press
Release Date : 2018-06-06
Antimicrobial Peptides In Gastrointestinal Diseases written by Chi Hin Cho and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-06 with Medical categories.
Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application
Role Of The Gut Flora In Toxicity And Cancer
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Author : I Rowland
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Role Of The Gut Flora In Toxicity And Cancer written by I Rowland and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Role of the Gut Flora in Toxicity and Cancer examines the relationship between the gut microflora and its host. The aim is to provide a comprehensive view of the contribution of the gut flora to foreign compound metabolism in man and laboratory animals. The object has been to relate this bacterial metabolism to toxic events occurring in mammals and to consider the interrelationships of bacterial and mammalian metabolic pathways. The early chapters are set the scene and provide a background to the sections on metabolism of specific groups of compounds which follow. Subsequent chapters encompass the bacterial metabolism of both xenobiotics and food components, and concentrate on those reactions which have actual or potential toxicological and/or clinical importance. The concluding chapters provide assessments of the role of the gut flora in the etiology of cancer, in particular from the point of view of the formation of carcinogens, mutagens, and promotors within the large bowel.