Generation And Effector Functions Of Regulatory Lymphocytes
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Generation And Effector Functions Of Regulatory Lymphocytes
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Author : Gregory R. Bock
language : en
Publisher: John Wiley & Sons
Release Date : 2004-01-19
Generation And Effector Functions Of Regulatory Lymphocytes written by Gregory R. Bock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-19 with Science categories.
Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a much more detailed picture of these cells, they are still highly controversial. Several unresolved issues responsible for this dilemma are discussed in this book: it is difficult to grow and clone such cells, their phenotypes and effector functions are diverse and can sometimes easily be lost, and it is not well understood how they interact with antigen-presenting cells. This book contains contributions from leading investigators from around the world, including lively discussion of the current state of the art in studies of regulatory lymphocytes. Topics featured are the physiological control of autoimmunity, the role of antigen-specific cells in various diseases and disease models and effector mechanisms. Therapeutic applications are considered, particularly for type 1 diabetes, tissue transplantation and the control of viral infection. This important and groundbreaking book should be of interest to all immunologists. Related Novartis Foundation symposia: 254 Immunoinformatics: bioinformatic strategies for better understanding of immune function Chair: Hans-Georg Rammensee 256 Cancer and inflammation Chair: Siamon Gordon
Lymphocyte Activation And Immune Regulation Ix
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Lymphocyte Activation And Immune Regulation Ix written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented. Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans. Novel methods of visualization of immune cells and immune systems are reviewed in Section III.
Regulatory T Lymphocytes
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Author : Benvenuto Pernis
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Regulatory T Lymphocytes written by Benvenuto Pernis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Regulatory T Lymphocytes documents the proceedings of a symposium on ""Regulatory T Lymphocytes"" held at Arden House on the Harriman Campus of Columbia University from June 8-10, 1979. The meeting was the fourth of the P&S Biomedical Sciences Symposia. Starting with the opening address on regulatory T lymphocytes and their antigen receptors, the remainder of the book presents the contributions made by researchers at the symposium. These contributions are organized into seven parts. Part I contains studies T cell receptors. Part II presents studies on T cell subpopulations. Parts III and IV examine helper T cells. Parts V and VI deal with suppressor T cells. Part VII contains papers on regulatory T cell circuits.
Defining Optimal Immunotherapies For Type 1 Diabetes
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Author : Gregory R. Bock
language : en
Publisher: John Wiley & Sons
Release Date : 2008-07-31
Defining Optimal Immunotherapies For Type 1 Diabetes written by Gregory R. Bock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-31 with Science categories.
This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). Brings together contributions from the leaders in the arena of clinical immunotherapy, not limited to the diabetes field exclusively, in order to delineate a road-map that would lead to future clinical trials. The book integrates information from human and animal studies. The book considers T1D within the broader context of autoimmune disease. The format contains several discussions, which address specific questions and provides guidelines for future strategies and solutions for discovering a cure.
Mechanisms Of Lymphocyte Activation And Immune Regulation Iii
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mechanisms Of Lymphocyte Activation And Immune Regulation Iii written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Recent advances in the understanding of the major events that shape the immune recog nition system have been remarkable. The analysis of immunoglobulin (Ig) gene organization and Ig repertoire diversification in lower vertebrates has provided new insight into this process in mammals. Similarly, the understanding of the early development of lymphocytes and of the acquisition of immunological tolerance has been aided by elegant studies in quail/chicken chimeras, using the power of the distinctive markers of the constitutive cells of these birds. Great strides have been made in understanding the role played by major histocompatibility complex (MHC) molecules in antigen presentation and in repertoire selec tion within the thymus. The use of transgenic mice expressing specific T-cell receptor (TCR) genes has elucidated the process of both positive and negative selection. In parallel, there has been considerable progress in our understanding of tolerance, based in part on the use of markers for the V fJ genes of T-cell receptors and in part on the analysis of the behavior of long term T-cell lines. This has led to the realization that both clonal deletion and clonal anergy may play critical roles in the maintenance of unresponsiveness to self antigen. Molecular analysis of the requirements for expression of membrane immunoglobulin molecules has revealed the existence of a complex that appears to be of critical importance in mediating signalling through Ig receptors. In addition, major insights have been obtained into the regulation of expression of genes of immunologic interest.
Lymphocyte Functional Crosstalk And Regulation
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Author : Anil Shanker
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-20
Lymphocyte Functional Crosstalk And Regulation written by Anil Shanker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-20 with categories.
Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004
Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
T Lymphocyte Differentiation Antigens Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
T Lymphocyte Differentiation Antigens Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
T-Lymphocyte Differentiation Antigens: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about T-Lymphocyte Differentiation Antigens in a concise format. The editors have built T-Lymphocyte Differentiation Antigens: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about T-Lymphocyte Differentiation Antigens in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of T-Lymphocyte Differentiation Antigens: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1976
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Medicine categories.
Cellular And Molecular Immunology E Book
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Author : Abul K. Abbas
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-05-06
Cellular And Molecular Immunology E Book written by Abul K. Abbas and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-06 with Medical categories.
Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. This reference is the up-to-date and readable textbook you need to master the complex subject of immunology. - Recognize the clinical relevance of the immunology through discussions of the implications of immunologic science for the management of human disease. - Grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. - Stay abreast of the latest advances in immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more. - Visualize immunologic processes more effectively through a completely revised art program with redrawn figures, a brighter color palette, and more 3-dimensional art. - Find information more quickly and easily through a reorganized chapter structure and a more logical flow of material.