Genetic Determinants Of Skeletal Diseases
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The Genetics Of Osteoporosis And Metabolic Bone Disease
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Author : Michael J. Econs
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-05-12
The Genetics Of Osteoporosis And Metabolic Bone Disease written by Michael J. Econs and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-05-12 with Medical categories.
The explosive growth in the field of molecular biology over the last two decades has started to make a great impact on clinical medicine. Genes have been cloned for diseases that were poorly understood only a decade ago. Additionally, investigators are increasingly aware that there are strong genetic components to complex disorders, such as osteoporosis, that are not classically thought of as genetic disorders. New insights into the pathogenesis of metabolic bone diseases have been obtained from investigations into the molecular biology of these diseases and new therapies will become available based on these new insights. In The Genefies of Osteoporosis and Metabolie Bane Disease, I have assembled an internationally renowned group of experts to write the various chapters. Each of the authors is an expert in his/her field who is currently performing research on the content of their chapter and have made important contributions to the understanding of the clinical fea tures and pathophysiology of metabolic bone disease and genetics. The first part of The Genefies of Osteoporosis and Metabolie Bane Disease addresses issues related to genetic contributions to the development of osteoporosis and the many factors that must be considered when searching for genesthat predispose to osteoporosis. The second sec tion addresses recent advances in the clinical and molecular biological aspects of inherited metabolic bone disorders. The last section reviews the latest techniques for finding genes that predispose to metabolic bone diseases.
Genetic Determinants Of Skeletal Diseases
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Author :
language : en
Publisher:
Release Date : 2015
Genetic Determinants Of Skeletal Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Genetics Of Bone Biology And Skeletal Disease
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Author : Rajesh V. Thakker
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Genetics Of Bone Biology And Skeletal Disease written by Rajesh V. Thakker and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Medical categories.
This book identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluations of treatments. The book is aimed at all students of bone biology and genetics, and with this in mind, it includes general introductory chapters on genetics and bone biology and more specific disease-orientated chapters, which comprehensively summarize the clinical, genetic, molecular genetic, animal model, functional and molecular pathology, diagnostic, counselling and treatment aspects of each disorder. Saves academic, medical, and pharma researchers time in quickly accessing the very latest details on a broad range of genetic bone issues, as opposed to searching through thousands of journal articles Provides a common language for bone biologists and geneticists to discuss the development of bone cells and genetics and their interactions in the development of disease Researchers in all areas bone biology and genetics will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays For those clinical researchers who are also MDs, correct diagnosis (and therefore correct treatment) of bone diseases depends on a strong understanding of the molecular basis for the disease
Skeletal And Genetic Determinants Of Osteoporosis
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Author : Angelique Elisabeth Adriana Maria Weel
language : en
Publisher:
Release Date : 2001
Skeletal And Genetic Determinants Of Osteoporosis written by Angelique Elisabeth Adriana Maria Weel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Bone Dysplasias
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Author : Jürgen W. Spranger
language : en
Publisher: Oxford University Press, USA
Release Date : 2018
Bone Dysplasias written by Jürgen W. Spranger and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
The definitive guide to genetic bone disorders, now revised and expanded with glossy photographs and radiographs.This updated and expanded fourth edition of Bone Dysplasias presents age-related radiographs, photographs and clinical guidelines for more than 250 rare constitutional skeletal diseases. Focusing on diagnostically essential imaging and clinical features, each chapter is supplemented with prognosticand therapeutic information, a guide to differential diagnoses, and a short list of the most relevant publications.Organized in accordance with the most recent International Nosology and Classification of Genetic Skeletal Disorders, this new Bone Dysplasias distills the insights of a small, world-class author team on diagnosis and clinical approaches to this most difficult class of disorders.
Genetic Determinants Of Peak Bone Mineral Density
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Author : Brasen
language : en
Publisher:
Release Date : 2010
Genetic Determinants Of Peak Bone Mineral Density written by Brasen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Bone Health And Osteoporosis
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Author : United States Public Health Service
language : en
Publisher:
Release Date : 2004-12
Bone Health And Osteoporosis written by United States Public Health Service and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12 with Health & Fitness categories.
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Environmental And Genetic Factors Affecting Bone Diseases And Phenotypes In Mouse Models
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Author : Wei Dong
language : en
Publisher:
Release Date : 2021
Environmental And Genetic Factors Affecting Bone Diseases And Phenotypes In Mouse Models written by Wei Dong and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
In conclusion, our studies on genetic and environmental factors regulating bone phenotypes and diseases have significant implications. Not only have they raised the concept of sexual dimorphism in disease, but they have highlighted the influence of genetic background on bone disease. The link between different sources of vitamins and immune-mediated disease is intriguing and warrants further research, as is the bone protective effect of BCP.
Genetic Determinants Of Bone Size In The Human Adult Skeleton
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Author : Ushadevi Chinappen-Horsley
language : en
Publisher:
Release Date : 2009
Genetic Determinants Of Bone Size In The Human Adult Skeleton written by Ushadevi Chinappen-Horsley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Bones categories.
Genetic Determinants Of Bone Mineral Density And Osteoporosis
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Author : John Peter Kemp
language : en
Publisher:
Release Date : 2013
Genetic Determinants Of Bone Mineral Density And Osteoporosis written by John Peter Kemp and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.