Genetically Engineered Viruses
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Genetically Engineered Viruses
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Author : Dr Eddie Blair
language : en
Publisher: Taylor & Francis
Release Date : 2023-05-31
Genetically Engineered Viruses written by Dr Eddie Blair and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-31 with Science categories.
This book combines an up-to-date summary of how best to genetically engineer viruses with an overview of basic virology. This unique combination makes it an invaluable research tool for virologists and molecular biologists seeking to exploit viruses for a range of applications. Written by highly respected authors, the book also provides comparisons to and guidelines for the use of viruses in difference applications.
Genetic Engineering Of Viruses And Viral Vectors
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Author : Proceedings of the National Academy of Sciences
language : en
Publisher: National Academies Press
Release Date : 1996-01-01
Genetic Engineering Of Viruses And Viral Vectors written by Proceedings of the National Academy of Sciences and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-01 with Nature categories.
Oncolytic Viruses Genetically Engineering The Future Of Cancer Therapy
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Author : Benjamin Gesundheit
language : en
Publisher: Frontiers Media SA
Release Date : 2016-11-22
Oncolytic Viruses Genetically Engineering The Future Of Cancer Therapy written by Benjamin Gesundheit and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-22 with categories.
The ability to genetically engineer oncolytic viruses in order to minimize side effects and improve the selective targeting of tumor cells has opened up novel opportunities for treating cancer. Understanding the mechanisms involved and the complex interaction between the viruses and the immune system will undoubtedly help guide the development of new strategies. Theranostic biomarkers to monitor these therapies in clinical trials serve an important need in this innovative field and demand further research.
Genetically Engineered Organisms
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Author : Deborah K. Letourneau
language : en
Publisher: CRC Press
Release Date : 2001-09-26
Genetically Engineered Organisms written by Deborah K. Letourneau and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-26 with Medical categories.
Genetic engineering suggests new avenues for constructing useful products, but it also poses hazards to the health of the environment and the public. Delineating those hazards is complicated, difficult, and important at every level of risk assessment and risk management decision-making. Risk assessment and risk management may be further complicated
New Directions For Biosciences Research In Agriculture
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1985-01-01
New Directions For Biosciences Research In Agriculture written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-01-01 with Technology & Engineering categories.
Authored by an integrated committee of plant and animal scientists, this review of newer molecular genetic techniques and traditional research methods is presented as a compilation of high-reward opportunities for agricultural research. Directed to the Agricultural Research Service and the agricultural research community at large, the volume discusses biosciences research in genetic engineering, animal science, plant science, and plant diseases and insect pests. An optimal climate for productive research is discussed.
Baculovirus Expression Vectors
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Author : David R. O'Reilly
language : en
Publisher:
Release Date : 1994
Baculovirus Expression Vectors written by David R. O'Reilly and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Baculoviruses have proven to be the most powerful and versatile eukaryotic expression vectors available. This unique laboratory manual is designed to help both beginning and experienced researchers construct and use baculovirus vector systems. It simplifies selection of the most appropriate baculovirus vector design for a given problem, then describes each step of the implementation process--from vector construction to large-scale protein production. The book provides an understanding of how the vectors work; a biological overview of cells, viruses, plasmids, and promoters; guidelines for choosing optimum vectors; protocols for growing insect cells and recombinant viruses; methods of analyzing protein products and scaling up protein production; techniques for producing proteins in insect larvae; and easy-to-use maps charting available expression vectors. This comprehensive approach has many benefits for researchers and students alike. It allows them to understand how and why the vector system works and offers a rapid comparison of options for choosing the right virus, plasmid or promoter for vector design and construction, with a minimum amount of lost time. The manual is an invaluable resource for every individual engaged in the production of proteins for any purpose.
Structural Biology Of Viruses
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Author : Wah Chiu
language : en
Publisher:
Release Date : 1997
Structural Biology Of Viruses written by Wah Chiu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Science categories.
Historically, structural biology and virology have been separate disciplines, with the field of virology developing around particular virus families. However, recent advances in the techniques of structural biology, including high-performance computing and graphics visualization, X-ray crystallography, and electron microscopy, coupled with continued progress in molecular biology and virology have caused a major convergence of interests. "Structural virology" now provides some of the most outstanding examples of structure-function relationships in biology. Viruses encounter many common problems in their life cycles, and so the solutions that they have evolved provide instructive contrasts between different biological strategies for survival. These ideas are illustrated by each of the different chapters, most of which cover a viral system that well illustrates a particular biological function. The goal of this book is to unite the structural and biological aspects of virus function. With this in mind, each chapter has been written explicitly by experts to address a broad audience ranging from graduate students to researchers in structural biology, virology, molecular biology, and biochemistry.
Genetic Engineering
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Author : Hugo Barrera-Saldaña
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-01-18
Genetic Engineering written by Hugo Barrera-Saldaña and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-18 with Science categories.
Leading scientists from different countries around the world contributed valuable essays on the basic applications and safety, as well as the ethical and moral considerations, of the powerful genetic engineering tools now available for modifying the molecules, pathways, and phenotypes of species of agricultural, industrial and even medical importance. After three decades of perfecting such tools, we now see a refined technology, surprisingly unexpected applications, and matured guidelines to avoid unintentional damage to our and other species, as well as the environment, while trying to contribute to solve the biological, medical and technical challenges of society and industry. Chapters on thermo-stabilization of luciferase, engineering of the phenylpropanoid pathway in a species of high demand for the paper industry, more efficient regeneration of transgenic soybean, viral resistant plants, and a novel approach for rapidly screening properties of newly discovered animal growth hormones, illustrate the state-of-the-art science and technology of genetic engineering, but also serve to raise public awareness of the pros and cons that this young scientific discipline has to offer to mankind.
Genetically Engineered Crops
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2016-12-28
Genetically Engineered Crops written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-28 with Science categories.
Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.
The Challenge Of Cmc Regulatory Compliance For Biopharmaceuticals
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Author : John Geigert
language : en
Publisher: Springer
Release Date : 2019-05-08
The Challenge Of Cmc Regulatory Compliance For Biopharmaceuticals written by John Geigert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-08 with Medical categories.
Biopharmaceuticals (i.e., biological medicines sourced from genetically-engineered living systems) for treatment of human diseases have become a significant percentage of the pharmaceutical industry. And not just the recombinant DNA-derived proteins and monoclonal antibodies (both from the innovators and biosimilars); but now, an increasing awareness of the importance of gene therapy and genetically engineered cellular medicinal products. These biopharmaceuticals are being developed by many companies whose Chemistry, Manufacturing & Control (CMC) teams have varying degrees of familiarity or experience with the CMC strategy and regulatory compliance requirements for these challenging products. Companies clearly plan out the strategy for their clinical study plans, but frequently, the development of a strategy for CMC is an afterthought. Coupled with the complexity of the biopharmaceutical manufacturing processes and products, and this can be a recipe for disaster. The third edition of this book provides insights and practical guidance for the CMC teams to develop an acceptable cost-effective, risk-based CMC regulatory compliance strategy for all biopharmaceuticals (recombinant proteins, monoclonal antibodies, genetically engineered viruses and genetically engineered human cells) from early clinical stage development through market approval. The third edition of this book provides added coverage for the biosimilars, antibody drug conjugates (ADCs), bispecific antibodies, genetically engineered viruses, and genetically engineered cells. This third edition of the book also addresses the heightened pressure on CMC regulatory compliance timelines due to the introduction of expedited clinical pathways moving the clinical development closer to a seamless phase process (e.g., FDA Breakthrough Therapy designation, CBER Regenerative Medicine Advanced Therapy (RMAT) designation, EMA Priority Medicines (PRIME) designation). The Challenge of CMC Regulatory Compliance for Biopharmaceuticals is essential, practical information for all pharmaceutical development scientists, Manufacturing and Quality Unit staff, Regulatory Affairs personnel, and senior management involved in the manufacture of biopharmaceuticals.