Genome Science Towards A New Paradigm
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Genome Science Towards A New Paradigm
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Author : Hiroshi Yoshikawa
language : en
Publisher: Excerpta Medica
Release Date : 2002
Genome Science Towards A New Paradigm written by Hiroshi Yoshikawa and has been published by Excerpta Medica this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
Present topics in genome science and collects the contributions for 32 experts in this field. This book explains how the genomes of many species, from bacteria to human, have been sequenced. It also delineates genome science, which replaces molecular biology, as a way to study the structure and dynamics of life.
Pan Cancer Integrative Molecular Portrait Towards A New Paradigm In Precision Medicine
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Author : Christophe Le Tourneau
language : en
Publisher: Springer
Release Date : 2015-08-27
Pan Cancer Integrative Molecular Portrait Towards A New Paradigm In Precision Medicine written by Christophe Le Tourneau and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-27 with Medical categories.
This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial. The authors are all members of the French Curie Institute, one of the world’s foremost cancer research institutions.
Pristionchus Pacificus
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Author :
language : en
Publisher: BRILL
Release Date : 2015-03-20
Pristionchus Pacificus written by and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-20 with Science categories.
This edited volume on the nematode model Pristionchus pacificus describes an integrative approach to evolutionary biology. It aims for a merger of evolutionary and comparative biology with mechanistic approaches based on genetics and molecular biology. Insight into the function of biological systems obtained from laboratory studies when complemented with ecology, natural variation and natural history of an organism, can provide detailed knowledge of the proximate and ultimate causations of species. Ralf J. Sommer developed P. pacificus as model system for integrative evolutionary biology with case studies in evo-devo and population genetics on La Réunion Island. Similarly, ecological interactions with scarab beetles revealed examples for the evolution of novelty at the morphological and behavioural level and their underlying molecular mechanisms. Contributors include Paul W. Sternberg, Ralf J. Sommer, Jagan Srinivasan, Christian Rödelsperger, Frank C. Schroeder, Robin M. Giblin-Davis, Natsumi Kanzaki, Matthias Herrmann, Angela McGaughran, Katy Morgan, Akira Ogawa, Federico D. Brown, Ray E. Hong, Robbie Rae, Amit Sinha, David Rudel, and Erik J. Ragsdale.
Nuclear Magnetic Resonance
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Author : G A Webb
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31
Nuclear Magnetic Resonance written by G A Webb and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.
As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Nucleic Acids" and "NMR of Carbohydrates, Lipids and Membranes". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an invaluable source of current methods and applications. Volume 33 covers literature published from June 2002 to May 2003. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Restriction Endonucleases
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Author : Alfred Pingoud
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Restriction Endonucleases written by Alfred Pingoud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.
Synthetic Biology
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Author : Christina Smolke
language : en
Publisher: John Wiley & Sons
Release Date : 2018-02-28
Synthetic Biology written by Christina Smolke and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-28 with Science categories.
A review of the interdisciplinary field of synthetic biology, from genome design to spatial engineering. Written by an international panel of experts, Synthetic Biology draws from various areas of research in biology and engineering and explores the current applications to provide an authoritative overview of this burgeoning field. The text reviews the synthesis of DNA and genome engineering and offers a discussion of the parts and devices that control protein expression and activity. The authors include information on the devices that support spatial engineering, RNA switches and explore the early applications of synthetic biology in protein synthesis, generation of pathway libraries, and immunotherapy. Filled with the most recent research, compelling discussions, and unique perspectives, Synthetic Biology offers an important resource for understanding how this new branch of science can improve on applications for industry or biological research.
Critical Perspectives On Ancient Dna
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Author : Daniel Strand
language : en
Publisher: MIT Press
Release Date : 2024-07-02
Critical Perspectives On Ancient Dna written by Daniel Strand and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-02 with Social Science categories.
The first comprehensive critical analysis of the practices and consequences of ancient DNA research. This edited collection, Critical Perspectives on Ancient DNA, presents a critical enquiry into the much-hyped “ancient DNA revolution” in archaeology. Offering the first comprehensive and in-depth scholarly analysis of the practices and effects of archaeogenetics, editors Daniel Strand, Anna Källén, and Charlotte Mulcare, along with other renowned scholars from Europe and the United States, address a host of questions, such as: What happens with our understanding of the past when archaeology is married to genetic science? What cultural forms and historical narratives are generated by ancient DNA (aDNA) research, and what energies could they unleash? Taking a multidisciplinary and multisite approach to the topic, these essays offer important insights into the epistemological, ethical, and political consequences around and beyond the scientific analysis of aDNA. As such, Critical Perspectives on Ancient DNA provides a timely and much-needed critical engagement with the rapidly growing field of aDNA research—a field that, while already having a notable impact on how we view the past in research, museums, and popular media—had not yet been subject to thorough critical scrutiny. Contributors Ruth Amstutz, Chip Colwell, Magnus Fiskesjö, K. Ann Horsburgh, Anna Källén, Stewart B. Koyiyumptewa, Amade M’charek, Charlotte Mulcare, Andreas Nyblom, Venla Oikkonen, Mélanie Pruvost, Marianne Sommer, Daniel Strand
Microbial Synthetic Biology
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Author :
language : en
Publisher: Elsevier
Release Date : 2013-11-06
Microbial Synthetic Biology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-06 with Science categories.
The 40th volume of Methods in Microbiology focuses on microbial synthetic biology.Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems.This volume addresses some of the major technical challenges stand in the way of achieving a radical step-change in our ability to engineer complex multi-scaled biological systems. These include: the application of computation intelligence to the design of synthetic microbial systems, design automation and constraints; the impact of noise and stochasticity; the engineering of biosensors; the characteristic of a model bacterial chassis. A key issue in Synthetic Biology is that of its social dimensions and a chapter is dedicated to the important issue. - Authority or expertise of contributors - lLnks to websites for the design and modelling of microbes and microbial metabolism - First volume to address the practical issues - Discussion on responsible innovation
Genome Chaos
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Author : Henry H. Heng
language : en
Publisher: Academic Press
Release Date : 2019-05-25
Genome Chaos written by Henry H. Heng and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-25 with Medical categories.
Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine. - Bridges basic research and clinical application and provides a foundation for re-examining the results of large-scale omics studies and advancing molecular medicine - Gathers the most pressing questions in genomic and cytogenomic research - Offers alternative explanations to timely puzzles in the field - Contains eight evidence-based chapters that discuss 4d-genomics, genes and genomes as distinct biological entities, genome chaos and macro-cellular evolution, evolutionary cytogenetics and cancer, chromosomal coding and fuzzy inheritance, and more
Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 1993
Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Environmental health categories.