Glial Cells Managers Of Neuro Immunity
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Glial Cells Managers Of Neuro Immunity
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Author : Carlos Barcia
language : en
Publisher: Frontiers Media SA
Release Date : 2016-05-30
Glial Cells Managers Of Neuro Immunity written by Carlos Barcia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-30 with Electronic book categories.
Immune responses within the brain are still scarcely explored. Nerve tissue damage is accompanied by the activation of glial cells, primarily microglia and astroglia, and such activation is responsible for the release of cytokines and chemokines that maintain the local inflammatory response and actively recruit lymphocytes and monocytes to the damaged areas. Theoretically, these responses are designed to repair the brain damage. However, alterations, or a chronic perpetuation of these responses may underlie a number of neuro-pathologies. It is thought that each inflammatory scenario within the brain have a specific biochemical footprint characterized by the release of determined cytokines, chemokines and growing factors able to define particular immunological responses. Alongside, glial cells transform their cell body, become larger and develop higher number of branches adopting an active morphological phenotype. These changes are related with the search of interactions with other cells, such as bystander resident cells of the brain parenchyma, but also cells homing from the blood stream. In this process, microglia and astrocytes communicates with other cells by the formation of specific intercellular connections that are still poorly understood. These interactions are complex and entail the arrangement of cytoskeletal compounds, secretory and phagocytic domains. In this particular crosstalk there is a two-way communication in which glial cells and target cells come together establishing interfaces with specific information exchange. This way, glial cells orchestrate the particular response recruiting cellular subsets within the central nervous system and organizing the resolution of the brain damage. In this Frontiers Research Topic, we compile a selection of articles unfolding diverse aspects of glial-derived inflammation, focused on neurodegenerative diseases and other nervous system disorders, with special emphasis on microglia/macrophages as leading actors managing neuro-immunity.
Glial Cells Managers Of Neuro Immunity
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Author :
language : en
Publisher:
Release Date : 2016
Glial Cells Managers Of Neuro Immunity written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Immune responses within the brain are still scarcely explored. Nerve tissue damage is accompanied by the activation of glial cells, primarily microglia and astroglia, and such activation is responsible for the release of cytokines and chemokines that maintain the local inflammatory response and actively recruit lymphocytes and monocytes to the damaged areas. Theoretically, these responses are designed to repair the brain damage. However, alterations, or a chronic perpetuation of these responses may underlie a number of neuro-pathologies. It is thought that each inflammatory scenario within the brain have a specific biochemical footprint characterized by the release of determined cytokines, chemokines and growing factors able to define particular immunological responses. Alongside, glial cells transform their cell body, become larger and develop higher number of branches adopting an active morphological phenotype. These changes are related with the search of interactions with other cells, such as bystander resident cells of the brain parenchyma, but also cells homing from the blood stream. In this process, microglia and astrocytes communicates with other cells by the formation of specific intercellular connections that are still poorly understood. These interactions are complex and entail the arrangement of cytoskeletal compounds, secretory and phagocytic domains. In this particular crosstalk there is a two-way communication in which glial cells and target cells come together establishing interfaces with specific information exchange. This way, glial cells orchestrate the particular response recruiting cellular subsets within the central nervous system and organizing the resolution of the brain damage. In this Frontiers Research Topic, we compile a selection of articles unfolding diverse aspects of glial-derived inflammation, focused on neurodegenerative diseases and other nervous system disorders, with special emphasis on microglia/macrophages as leading actors managing neuro-immunity.
Neuroimmune Interactions
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Author : Chester Robinson
language : en
Publisher:
Release Date : 2022-09-13
Neuroimmune Interactions written by Chester Robinson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-13 with categories.
The system of processes and structures which consists of interactions between the nervous system and the immune system is termed as the neuroimmune system. It involves electrophysiological and biochemical processes, and is integral in protecting the neurons from pathogens. Sensory neurons and immune cells are used by the neuroimmune system for the detection and management of harmful stimuli. The neuroimmune system is primarily comprised of glial cells. Neurons and glial cells work together to deal with attacking pathogens. Both glial cells and neurons express chemokine receptors, thus chemokines act as mediators in neuron-glial cell interaction. Different approaches, evaluations, methodologies and advanced studies on neuroimmune interactions and their clinical aspects have been included in this book. It presents this complex subject in the most comprehensible and easy to understand language. This book will serve as a valuable source of reference for graduate and post graduate students.
Neuroinflammation Mechanisms And Management
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Author : Alfred Galswells
language : en
Publisher: American Medical Publishers
Release Date : 2021-11-16
Neuroinflammation Mechanisms And Management written by Alfred Galswells and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.
Inflammation is the biological response towards pathogens and damaged cells exhibited by the body tissues. The inflammation of the nervous tissues is known as neuroinflammation. It may occur in response to a number of causes such as infection, toxic metabolites or traumatic brain injury. Brain and spinal cord, that make the central nervous system, have immune cells known as microglia. These cells are activated during neuroinflammation. It usually refers to the chronic inflammation of the central nervous system, instead of acute inflammation. During chronic inflammation, there is a sustained activation of glial cells and recruitment of other immune cells into the brain. Some other causes of chronic neuroinflammation are ageing, air pollution, passive smoking, spinal cord injury and microbes. This book traces the progress in the field of neuroscience in relation to the management and mechanisms in neuroinflammation. Also included herein is a detailed explanation of the various aspects of this disease. This book aims to equip students and experts with the advanced topics in this disease.
Management Of Dysregulated Immune Response In The Critically Ill
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Author : Zsolt Molnar
language : en
Publisher: Springer Nature
Release Date : 2023-03-11
Management Of Dysregulated Immune Response In The Critically Ill written by Zsolt Molnar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-11 with Medical categories.
This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.
Diagnosis And Management Of Head And Face Pain
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Author : James Y. Suen
language : en
Publisher: Springer
Release Date : 2018-07-20
Diagnosis And Management Of Head And Face Pain written by James Y. Suen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-20 with Medical categories.
This text is a comprehensive guide to the evaluation of patients with head and face pain. It is a resource for any physician or dentist to properly diagnosis and to learn the options for treating head and face pain, as well as know when to refer a patient to a specialist and how to identify which specialist is needed. It discusses the basic anatomy, etiology, and pathophysiology of head and face pain, classification guidelines for treatment, and clinical case examples. Additional chapters on nerve blocks, nerve stimulators, radiosurgery, microvascular decompression, Botox, and alternative and complementary medicine are also included. Diagnosis and Management of Head and Face Pain will be an invaluable resource for otolaryngologists, family physicians, oral surgeons, dentists, neurologists, neurosurgeons, pain specialists, and patients who suffer from head and face pain.
Strengthening School Counselor Advocacy And Practice For Important Populations And Difficult Topics
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Author : Rausch, Meredith A.
language : en
Publisher: IGI Global
Release Date : 2021-01-29
Strengthening School Counselor Advocacy And Practice For Important Populations And Difficult Topics written by Rausch, Meredith A. and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-29 with Education categories.
School counselors often struggle to feel confident in delivering effective assistance to students due to a variety of reasons that currently do not have enough research or information developed. This leads to a struggle for counselors to adequately address tough and relevant issues. With these issues remaining unaddressed, or addressed less effectively, there is a concern that school counselors cannot mitigate these issues due to not being adequately informed. This can lead to a lifetime of consequences for students. Strengthening School Counselor Advocacy and Practice for Important Populations and Difficult Topics presents emerging research that seek to answer the tough and often unaddressed questions, target present-day issues of student populations, and prepare school counselors to feel confident and competent in their counseling and advocacy practice. These chapters, using the newest information available, will address these concerns and provide the best counseling work possible for underserved populations. While covering research on counseling for students with chronic illnesses, mixed-statuses, family issues, minority students, LGBTQ+ youth, and more, this book is ideal for school counselors, counseling educators, practitioners, stakeholders, researchers, academicians, and students who are interested in school counseling and meeting the needs of diverse and important populations of students.
Clinical Pain Management Acute Pain
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Author : Pamela Macintyre
language : en
Publisher: CRC Press
Release Date : 2008-09-26
Clinical Pain Management Acute Pain written by Pamela Macintyre and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-26 with Health & Fitness categories.
Acute Pain brings coverage of this diverse area together in a single comprehensive clinical reference, from the basic mechanisms underlying the development of acute pain, to the various treatments that can be applied to control it in different clinical settings. Much expanded in this second edition, the volume reflects the huge advances that contin
Core Curriculum For Pain Management Nursing E Book
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Author : Aspmn
language : en
Publisher: Elsevier Health Sciences
Release Date : 2024-10-13
Core Curriculum For Pain Management Nursing E Book written by Aspmn and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-13 with Medical categories.
Prepare for the nurse's role in assessing and managing pain! Core Curriculum for Pain Management Nursing, 4th Edition uses an easy-to-read outline format to cover the entire scope of pain management. Written by the American Society of Pain Management Nurses (ASPMN(R), the leading nursing organization in pain management), this review begins with foundational concepts and follows with guidelines and tools for effective pain assessment. Coverage of evidence-based pain management strategies and therapies is included for all patient types and ages. Updated to reflect current best practices in nursing, this book provides an excellent review for the ASPMN(R) pain management certification exam and the RN-BC credentialing exam. Content written by ASPMN(R) ensures that information includes the latest in education, research, standards, and practice, as well as a thorough review for the ASPMN(R) certification exam and the RN-BC credentialing exam.. Both pharmacologic and non-pharmacologic methods of pain management are described. Comprehensive coverage includes adult, pediatric, and geriatric patients along with key subsets of patients such as those who have concomitant addiction, those who have cancer, and those who are under sedation for a procedure. Wide-ranging content includes disparities in pain management, the roles of the clinical nurse specialist as well as the nurse practitioner, theories of pain management, the use of research, gender differences in how men and women respond to pain and analgesia, and the effect of depression on pain perception and management. Strong nursing focus provides guidelines for the nurse's role in pain management and in improving the quality of patient care. Easy-to-read outline format makes this book a quick and accessible reference. NEW! Updated content includes the latest changes in clinical practice including pharmacologic and non-pharmacologic pain interventions, integrative and complementary therapies, and the current ANA scope and standards of practice. NEW! Revised chapters include Mental Health Disorders and Pain and Managing Pain in the Context of Substance Use Disorder. NEW! Cannabis Use in Pain Management chapter is added to this edition. NEW! Reorganized content better highlights the complexity of assessment and management of pain. NEW two-color design, illustrations, and summary tables are added throughout the book, making difficult concepts easier to understand and remember.
Diagnosis Management Of Neurological Disorders
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Author : U K Misra
language : en
Publisher: Wolters kluwer india Pvt Ltd
Release Date : 2011-01-01
Diagnosis Management Of Neurological Disorders written by U K Misra and has been published by Wolters kluwer india Pvt Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-01 with Medical categories.
This book presents an authoritative exposition of the clinical presentation, diagnosis and treatment of neurological disorders. Covering both infectious and non-infectious disorders, the book specially emphasizes the regional variations in the epidemiology, manifestation and management of these disorders in tropical and resource-limited countries.