Guidelines For The Testing Of Chemicals For Carcinogenicity
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Guidelines For The Testing Of Chemicals For Carcinogenicity
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Author : Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment
language : en
Publisher:
Release Date : 1982
Guidelines For The Testing Of Chemicals For Carcinogenicity written by Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Carcinogenicity testing categories.
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 453 Combined Chronic Toxicity Carcinogenicity Studies
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-06-27
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 453 Combined Chronic Toxicity Carcinogenicity Studies written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with categories.
The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 451 Carcinogenicity Studies
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-06-27
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 451 Carcinogenicity Studies written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with categories.
The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...
Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Guidance Notes For Analysis And Evaluation Of Chronic Toxicity And Carcinogenicity Studies
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2002-12-12
Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Guidance Notes For Analysis And Evaluation Of Chronic Toxicity And Carcinogenicity Studies written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-12 with categories.
These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.
Oecd Series On Testing And Assessment Guidance Document 116 On The Conduct And Design Of Chronic Toxicity And Carcinogenicity Studies Supporting Test Guidelines 451 452 And 453 Second Edition
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2014-09-03
Oecd Series On Testing And Assessment Guidance Document 116 On The Conduct And Design Of Chronic Toxicity And Carcinogenicity Studies Supporting Test Guidelines 451 452 And 453 Second Edition written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-03 with categories.
This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.
Carcinogenicity
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Author : Kirk T. Kitchin
language : en
Publisher: CRC Press
Release Date : 2021-12-16
Carcinogenicity written by Kirk T. Kitchin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-16 with Science categories.
Offers comprehensive coverage of currently available cancer predictors, the most recent research on carcinogenicity, and the design and interpretation of carcinogenicity experiments. Presents mouse, rat, and human carcinogenicity data for the liver, kidney, breast, cervix, prostate, hematopoietic system, colon, skin, urinary bladder, mouth, stomach, thyroid, and pancreas.
Genotoxicity And Carcinogenicity Testing Of Pharmaceuticals
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Author : Michael J. Graziano
language : en
Publisher: Springer
Release Date : 2015-11-02
Genotoxicity And Carcinogenicity Testing Of Pharmaceuticals written by Michael J. Graziano and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-02 with Medical categories.
This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. It includes a review of relevant ICH guidelines, numerous case studies where follow-up studies were conducted to further investigate positive findings, and practical considerations for the use of alternative and emerging tests. With contributions from recognized experts in the pharmaceutical industry and health authorities, this volume presents a balanced view on the interpretation and application of genotoxicity and carcinogenicity regulatory guidances. Genotoxicity and Carcinogenicity Testing of Pharmaceuticals is a valuable resource for scientists, regulators, and consultants that are engaged in the conduct, reporting, and review of nonclinical studies. This book will also help academicians better understand and appreciate the complexity of the regulations and breadth of toxicology research that are necessary to support the development and marketing of new drugs.
Toxicological Risk Assessment Of Chemicals
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Author : Elsa Nielsen
language : en
Publisher: CRC Press
Release Date : 2008-02-21
Toxicological Risk Assessment Of Chemicals written by Elsa Nielsen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-21 with Medical categories.
Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 452 Chronic Toxicity Studies
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-06-27
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 452 Chronic Toxicity Studies written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with categories.
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
Identifying And Regulating Carcinogens
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Author : Lewis Publishers
language : en
Publisher: CRC Press
Release Date : 2018-02-01
Identifying And Regulating Carcinogens written by Lewis Publishers and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-01 with Science categories.
This excellent resource describes the various Federal agency programs, guidelines, laws, and requirements regarding potential exposure to carcinogens in the environment-ambient air, water, and soil-workplace environment-food and drugs and other consumer products. It covers 16 different programs, activities, and Federal agencies. The reader is provided insight into the background and rationale behind current Federal Policy and regulations relating to public health and potential carcinogenic hazards. Necessary differentiation among Hazard Identification, risk characterization, risk assessment, and risk management are clearly described. This guide should prove valuable to scientists, engineers, and managers-companies, governments, universities, and consultants.