Handbook Of Reagents For Organic Synthesis Reagents For High Throughput Solid Phase And Solution Phase Organic Synthesis
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Handbook Of Reagents For Organic Synthesis
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Author : André B. Charette
language : en
Publisher: John Wiley & Sons
Release Date : 2015-07-15
Handbook Of Reagents For Organic Synthesis written by André B. Charette and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-15 with Science categories.
Heteroarenes are among the most prevalent structural units in natural products, pharmaceuticals, agrochemicals, and other compounds of scientific or commercial interest. In the last decade, a broad range of novel synthetic methods has been developed to not only facilitate construction of the heteroarene motif, but to enable its modification through direct C H functionalization. This Handbook describes 117 key reagents for selective heteroarene functionalization reactions, including both traditional and transition metal-catalyzed C H functionalization. Since these reactions typically involve one heteroarene, a coupling partner and a catalyst, the handbook not only focuses on the catalyst itself but also contains other key reaction species. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 117 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.
Handbook Of Reagents For Organic Synthesis
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Author : Tomislav Rovis
language : en
Publisher: John Wiley & Sons
Release Date : 2016-10-20
Handbook Of Reagents For Organic Synthesis written by Tomislav Rovis and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-20 with Science categories.
Spurred by the desire to make chemistry a sustainable and "greener" technology, the field of organocatalysis has grown to become one of the most important areas in synthetic organic chemistry. Organic catalysts can often replace potentially toxic metal catalysts and allow reactions to proceed under mild reaction conditions, thereby saving energy costs and rendering chemical processes inherently safer. More importantly perhaps, organocatalysis offers a complementary reactivity in many instances leading to increased versatility. This Handbook describes 126 key reagents for organocatalytic reactions and will be especially useful for professionals in the area of sustainable chemistry, medicinal research, as well as synthetic organic chemists working in academia and the pharmaceutical industry. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 126 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.
Reagents For Radical And Radical Ion Chemistry
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Author : David Crich
language : en
Publisher: Wiley
Release Date : 2009-01-07
Reagents For Radical And Radical Ion Chemistry written by David Crich and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-07 with Science categories.
Radicals and radical ions are important intermediates with wide use in organic synthesis. The first book to concentrate on reagents for the creation and use of radicals and radical ions, this new volume in the Handbooks of Reagents for Organic Synthesis series compiles articles taken from the e-eros database, on reagents for use in radical and radical chemistry, to help the chemist in the lab choose the right reagents. Reflecting the enormous growth of radical chemistry over the past ten years, this is an essential guide for all synthetic chemists.
Reagents For Silicon Mediated Organic Synthesis
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Author : Philip L. Fuchs
language : en
Publisher: John Wiley & Sons
Release Date : 2011-11-07
Reagents For Silicon Mediated Organic Synthesis written by Philip L. Fuchs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-07 with Technology & Engineering categories.
Over the last three decades the importance of organosilicon chemistry has greatly increased because it has opened a number of new synthetic strategies. Silicon reagents are usually low-cost, versatile and allow a wide range of reactions. This is the first Handbook to compile essential Silicon containing reagents and makes use of the leading reagent database e-EROS. Another hot volume in the series Handbooks of Reagents for Organic Synthesis, this is a must-have resource for all synthetic chemists working in drug development and medicinal chemistry. For the selection the Editor focussed on three key synthetic approaches with the greatest impact: 1. Use of silicon as a 'temporary tether' by unifying a reactive pair of functional groups and taking advantage of their template-biased intramolecular cyclization. 2. The specific use of the silane functionality as a hetero t-butyl group, often colloquially referred to as the use of silicon as a 'fat proton'. 3. The use of the Brook rearrangement as an 'anion relay stratagem'. A new feature in this Handbook is the reagent finder, an alphabetically organized lookup table arranged by organic functionality and specific structure of the silicon atom to which it is bound.
High Throughput Analysis In The Pharmaceutical Industry
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Author : Perry G. Wang
language : en
Publisher: CRC Press
Release Date : 2008-08-20
High Throughput Analysis In The Pharmaceutical Industry written by Perry G. Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-20 with Medical categories.
The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a toll booth. In order to break the bottleneck, a corres
High Throughput Synthesis
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Author : Irving Sucholeiki
language : en
Publisher: CRC Press
Release Date : 2001-02-22
High Throughput Synthesis written by Irving Sucholeiki and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-02-22 with Science categories.
An exploration of high-throughput synthesis, this book presents a compilation of how-to methods, novel materials, and catalyst developments for creating a multitude of new compounds. Introductory sections are coupled with in-depth case studies clarifying theory through practice. The book emphasizes the potential for reproducing experiments in detail.
Handbook Of Reagents For Organic Synthesis
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Author :
language : en
Publisher:
Release Date : 1999
Handbook Of Reagents For Organic Synthesis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Chemical tests and reagents categories.
Handbook Of Reagents For Organic Synthesis Reagents For High Throughput Solid Phase And Solution Phase Organic Synthesis
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Author : Jonathan A. Ellman
language : en
Publisher: Wiley
Release Date : 2005-05-20
Handbook Of Reagents For Organic Synthesis Reagents For High Throughput Solid Phase And Solution Phase Organic Synthesis written by Jonathan A. Ellman and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-20 with Science categories.
Since its discovery in 1963 by R. B. Merrifield, solid-phase synthesis, or polymer-supported synthesis, has become an essential technique with its wide use in the synthesis of peptides and other oligomers. Solid-Phase Reactions provides extensive and comprehensive information on this form of synthesis in a format ideal for those working in the laboratory. As part of the Handbook of Reagents in Organic Synthesis Series, this new addition extends the wealth of information available to the chemist at the bench. All content has been expertly collected and presented by an internationally recognised and respected editorial board led by Professor Peter Wipf.
Sulfur Containing Reagents
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Author : Leo A. Paquette
language : en
Publisher: John Wiley & Sons
Release Date : 2013-05-30
Sulfur Containing Reagents written by Leo A. Paquette and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-30 with Science categories.
There are a lot of books available about the chemistry and biology of sulfur. However, this is the first book with a compilation of all relevant Sulfur containing reagents. Synthetic chemists, most particularly in the medicinal and pharmaceutical chemists, are often called upon to prepare compounds that contain Sulfur as a key structural feature. In the past, this seemed to be a domain for specialists; today every synthetic chemist working in these area is expected to synthesize compounds containing sulfides, sulfates, sulfones, etc. This book offers an important source of information for the selection and handling of the right reagents.
Catalytic Oxidation Reagents
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Author : Philip L. Fuchs
language : en
Publisher: John Wiley & Sons
Release Date : 2013-07-29
Catalytic Oxidation Reagents written by Philip L. Fuchs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-29 with Science categories.
The Handbook is part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis. The Handbook starts with a section discussing the most important aspects of heteroarene functionalization. The introduction is followed by the alphabetical listing of the most relevant reagents drawn from the EROS database. The Editor, André Charette from the University of Montreal, has selected 120 reagent descriptions, many of them updated with heteroarene-specific reactions for this Handbook. Following the standard format for EROS, each article contains an overview of the synthesis and physical properties of the reagents or catalyst, conditions for its storage, and purification methods. Given the importance of heteroarenes in biology and especially in medicinal chemistry, a Handbook that focuses exclusively on heteroarene functionalization has been long overdue. This Handbook will have a broad appeal to many individuals engaged in the area of medicinal chemistry, fine chemical synthesis and industrial-scale chemistry. Key features: Builds on the success of the previously published Handbooks of Reagents for Organic Synthesis Compares the numerous new C-H functionalization reactions that have been developed in the past decade Heteroarene functionalization is widely used in the development of pharmaceuticals and other bioactive compounds Contains listings of secondary reagents for which more information is available in the online edition