Handbook Of Statistical Genetics 1

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Handbook Of Statistical Genetics 1 2007

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Author : David J. Balding
language : en
Publisher:
Release Date : 2007

Handbook Of Statistical Genetics 1 2007 written by David J. Balding and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.

Handbook Of Statistical Genetics

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Author : David J. Balding
language : en
Publisher: John Wiley & Sons
Release Date : 2008-06-10

Handbook Of Statistical Genetics written by David J. Balding and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-10 with Science categories.

The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.

Handbook Of Statistical Genetics 1

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Author : David J. Balding
language : en
Publisher:
Release Date : 2003

Handbook Of Statistical Genetics 1 written by David J. Balding and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Genetics categories.

Handbook Of Statistical Genomics

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Author : David J. Balding
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-10

Handbook Of Statistical Genomics written by David J. Balding and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-10 with Science categories.

A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Handbook Of Statistical Genetics

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Author : D. J. Balding
language : en
Publisher:
Release Date : 2001-03-28

Handbook Of Statistical Genetics written by D. J. Balding and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-28 with Mathematics categories.

A truly groundbreaking volume, the Handbook of Statistical Genetics is a timely, informative and highly accessible reference for both statisticians interested in genetical applications and geneticists seeking a deeper understanding of statistical methods in their field. It is divided into six main sections, encompassing the entire field of statistics in genetics: ? Bioinformatics ? Population Genetics ? Evolutionary Genetics ? Genetic Epidemiology ? Plant and Animal Genetics ? Applications As the Human Genome Project (HGP) reaches its climax, with the complete sequence of mankind, science is fast approaching an exciting new stage in its ability to understand genetic forces in man. In parallel to the HGP are major sequencing efforts in other organisms, enabling us to understand broader questions in evolution and classification. This explosion of data has led to an increased need for sophisticated statistical, mathematical and computational tools to enable complex data collection, analysis and interpretation of the results. ? Comprehensive coverage of the most pressing statistical issues in genetics. ? Offers a lucid introduction to newcomers, as well as providing invaluable information for more experienced researchers. ? Each chapter is written by a leading international authority from the field. ? Complemented by numerous examples, case studies, and references to useful resources on the web. This authoritative reference will be ideal for both students and researchers working in genetics, including statisticians, geneticists, molecular biologists, biochemists and computer scientists.

Teaching Epidemiology

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Author : Jorn Olsen
language : en
Publisher: OUP Oxford
Release Date : 2010-06-25

Teaching Epidemiology written by Jorn Olsen and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-25 with Medical categories.

Teaching epidemiology requires skill and knowledge, combined with a clear teaching strategy and good pedagogic skills. The general advice is simple: if you are not an expert on a topic, try to enrich your background knowledge before you start teaching. Teaching Epidemiology, third edition helps you to do this, and by providing the world-expert teacher's advice on how best to structure teaching gives a unique insight in to what has worked in their hands. The book will help you plan your own tailored teaching program. The book is a guide to new teachers in the field at two levels; those teaching basic courses for undergraduates, and those teaching more advanced courses for students at postgraduate level. Each chapter provides key concepts and a list of key references. Subject specific methodology and disease specific issues (from cancer to genetic epidemiology) are dealt with in details. There is also a focused chapter on the principles and practice of computer-assisted learning.

Gene Genealogies Variation And Evolution A Primer In Coalescent Theory

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Author : Jotun Hein
language : en
Publisher: Oxford University Press, USA
Release Date : 2004-12-09

Gene Genealogies Variation And Evolution A Primer In Coalescent Theory written by Jotun Hein and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-09 with Population genetics categories.

Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation. Rich in examples and illustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends with chapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies. Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and students studying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. - Professor Montgomery Slatkin (Berkeley);the authors are outstanding experts in the field, and the book is topical and timely. - Professor David Balding (Imperial College);Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. - Professor Joe Felsenstein (University of Washington)

Biological Data Mining And Its Applications In Healthcare

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Author : Xiaoli Li
language : en
Publisher: World Scientific
Release Date : 2013-11-28

Biological Data Mining And Its Applications In Healthcare written by Xiaoli Li and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-28 with Science categories.

Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains.

Genes And Common Diseases

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Author : Alan Wright
language : en
Publisher: Cambridge University Press
Release Date : 2007-08-02

Genes And Common Diseases written by Alan Wright and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-02 with Medical categories.

This book examines the role of genetics in modern medicine, reflecting the strengths and limitations of a genetic perspective.

Linear Selection Indices In Modern Plant Breeding

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Author : J. Jesus Céron-Rojas
language : en
Publisher: Springer
Release Date : 2018-09-26

Linear Selection Indices In Modern Plant Breeding written by J. Jesus Céron-Rojas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-26 with Science categories.

This open access book focuses on the linear selection index (LSI) theory and its statistical properties. It addresses the single-stage LSI theory by assuming that economic weights are fixed and known - or fixed, but unknown - to predict the net genetic merit in the phenotypic, marker and genomic context. Further, it shows how to combine the LSI theory with the independent culling method to develop the multistage selection index theory. The final two chapters present simulation results and SAS and R codes, respectively, to estimate the parameters and make selections using some of the LSIs described. It is essential reading for plant quantitative geneticists, but is also a valuable resource for animal breeders.