Hepatitis C Virus Treatment
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Chronic Hepatitis C Virus
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Author : Mitchell L. Shiffman
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-17
Chronic Hepatitis C Virus written by Mitchell L. Shiffman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-17 with Medical categories.
Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.
Current Management Of Hepatitis C Virus An Issue Of Clinics In Liver Disease
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Author : Fred Poordad
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-01-07
Current Management Of Hepatitis C Virus An Issue Of Clinics In Liver Disease written by Fred Poordad and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-07 with Medical categories.
Clinical information about Hepatitis C is quickly outdated, so Dr. Poordad has assembled expert authors to provide state-of-the-art clinjcal reviews for hepatologists. This issue is uniquely organized to present articles based on therapeutic regimens for certain types of patients: Regimens for the Treatment-Naïve Patient; Regimens for Treatment of the Interferon-Failure Patient; Regimens for DAA Failure Patients; Regimens for the Cirrhotic Patient; Regimens for the Peri-Transplant Patient; Regimens for the HIV-Co-Infected Patient; and Next-generation Regimens: The Future of HCV Therapy. This presentation will be very clinically relevant for the practicing hepatologist.
Update On Hepatitis C
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Author : Martina Smolic
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-10-04
Update On Hepatitis C written by Martina Smolic and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-04 with Medical categories.
In the past few years, remarkable progress has been made in our understanding of HCV biology, pathogenesis of infection, and structure-function relationships. This has led to quantum advances in clinical efficacy and tolerability. Yet, in spite of this amazing progress, there remain obstacles to widespread successful treatment. These issues include biological failures even with direct-acting agents, lack of options for individual with organ failures, drug-drug interactions, access to medications either due to lack of availability or affordability, and psychiatric and social issues. These problems are likely to remain in the future. Therefore, this book has been created by distinguished faculties from around the world to address the progress in our understanding of HCV infection and to review new treatment options, limitations, and accessibility of new therapeutic options.
Hepatitis C Virus Treatment
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Author : Kazuaki Chayama
language : en
Publisher: Springer
Release Date : 2016-11-01
Hepatitis C Virus Treatment written by Kazuaki Chayama and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-01 with Medical categories.
This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects. Hepatitis C Virus Treatment offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the characteristics of resistance, providing cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students.
Care Of The Patient With Hepatitis C Virus Infection An Issue Of Infectious Disease Clinics E Book
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Author : Barbara McGovern
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-10-31
Care Of The Patient With Hepatitis C Virus Infection An Issue Of Infectious Disease Clinics E Book written by Barbara McGovern and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-31 with Medical categories.
Hepatitis C infection can be an acute or chronic illness and is the most common cause of liver disease in the US. It often goes undiagnosed until significant organ damage has occurred. This issue of the ID Clinics discusses the staging of liver disease, treatments for those newly diagnosed, and those who are dealing with chronic illness, along with managing drug therapy and virus resistance.
Chronic Hepatitis C Virus
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Author : Mitchell L. Shiffman
language : en
Publisher: Springer
Release Date : 2012-02-10
Chronic Hepatitis C Virus written by Mitchell L. Shiffman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-10 with Medical categories.
Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.
Handbook Of Hepatitis C
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Author : Nicolas Goossens
language : en
Publisher: Springer
Release Date : 2016-05-25
Handbook Of Hepatitis C written by Nicolas Goossens and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-25 with Medical categories.
This book is a concise and up-to-date review of the clinical features, pathophysiology, diagnosis, and treatment of patients with hepatitis C. Busy health care professionals who want a quick review of hepatitis C and new developments in treatment for hepatitis C will benefit from this succinct guide. Hepatitis C virus primarily infects liver cells and can lead to chronic damage to the liver. Patients with hepatitis C infection often develop liver sequelae such as fibrosis, cirrhosis, and hepatocellular carcinoma if left untreated. It is estimated that 150 million people worldwide are infected with hepatitis C virus, and if eradication is to be achieved it is imperative to diagnose and treat such individuals.
Hepatitis C Virus Advances In Research And Treatment 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Hepatitis C Virus Advances In Research And Treatment 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Hepatitis C Virus: Advances in Research and Treatment: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Hepatitis C Virus in a concise format. The editors have built Hepatitis C Virus: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hepatitis C Virus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hepatitis C Virus: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Hepatitis C
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Author : Imran Shahid
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-10-10
Hepatitis C written by Imran Shahid and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-10 with Medical categories.
The propagation of hepatitis C from acute to chronic infection and afterward to end-stage liver diseases (hepatic fibrosis, cirrhosis, and hepatocellular carcinoma) involves a highly orchestrated series of molecular and cellular events, including a plethora of genes and cell signaling cascades. The treatment paradigms was revolutionized after the development and approval of all oral interferon-free direct-acting antivirals achieving higher sustained virologic response rates in treated individuals. This book pragmatically overviews the intricate interplay between viral and host factors during hepatitis C virus infection progression, as well as other hepatitis C-associated clinical implications. Hepatitis C - From Infection to Cure also provides up-to-date information about hepatitis C cures for clinicians, physicians, and healthcare providers with an ample understanding of the current treatment horizon, as well as other investigational and emerging treatment strategies. The authors with their valuable scientific contributions belong to many eminent institutes around the world and are much experienced in hepatitis C virology, pathology, and therapeutics.
Hepatitis C Virus Host Interactions And Therapeutics Current Insights And Future Perspectives
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Author : Imran Shahid
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-01-24
Hepatitis C Virus Host Interactions And Therapeutics Current Insights And Future Perspectives written by Imran Shahid and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-24 with Medical categories.
The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepatitis C virus infection. Despite advances in the treatment of HCV, therapeutic gaps remain that are yet to be fully explored. Researchers and scientists still strive to understand virus-host interactions to map the disease’s progression along with extrahepatic manifestations and virus invasion strategies impacting the host’s immune system. This book briefly discusses the biology of HCV infection, virus-host interactions, molecular epidemiology of the infection, and the full spectrum of immune responses to hepatitis C. It also provides in-depth information about HCV, clinical diagnostics, and therapeutic knowledge to all stakeholders involved in HCV screening, diagnosis, treatment, and management. Topics covered in the chapters include 1) HCV-host interactions leading to asymptomatic acute infection, 2) the progression of acute HCV infection to chronic disease and subsequent extrahepatic comorbidities, 3) Innate and adaptive immune responses in HCV infections, 4) Consensus-based Approaches for Hepatitis C Screening and Diagnosis, 5) advances in hepatitis C therapy and global management of HCV, and 6) the outcomes of Oral Interferon-free Direct-acting Antivirals as Combination Therapies to Cure Hepatitis C. This book is a valuable addition to undergraduate and postgraduate hepatology students and physicians, clinicians, hepatologists, and health care officials involved in HCV clinical diagnosis and therapeutics.