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Hormone Receptors


Hormone Receptors
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Hormone Receptors Structures And Functions


Hormone Receptors Structures And Functions
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-09-01

Hormone Receptors Structures And Functions written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-01 with Science categories.


Hormone Receptors: Structures and Functions, Volume 123 in the Vitamins and Hormones series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Updated release includes the latest information on Hormone Receptors



Development Of Hormone Receptors


Development Of Hormone Receptors
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Author : G. Csaba
language : en
Publisher: Birkhäuser
Release Date : 2013-03-12

Development Of Hormone Receptors written by G. Csaba and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Science categories.




Steroid Hormone Receptors Basic And Clinical Aspects


Steroid Hormone Receptors Basic And Clinical Aspects
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Author : V. K. Moudgil
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-13

Steroid Hormone Receptors Basic And Clinical Aspects written by V. K. Moudgil and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Medical categories.


The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of the hor mones as well their suggested involvement in several clinical conditions. In the recent past, notable scientific and technological advances have been made in the areas of contraception and regulation of fertility. Steroid receptors are the indis pensable mediators of hormonal responses and are complex protein molecules which appear to exist in association with other, yet undefined, proteins and/or factors. Receptors for vitamin D, retinoic acid and the thyroid hormones share structural similarities with steroid receptors, and the roster of this superfamily is still expanding. While our knowledge of the diversity and magnitude of steroid effects has advanced, the precise mode of steroid hormone action has alluded investigators. This volume brings together an international team of prominent investigators who discuss their most recent work on the basic and clinical aspects of steroid/nuclear receptors. The contributions represent updated versions of the invited presentations made at The Second Meadow Brook Conference on Steroid Receptors in Health and Disease. I am grateful to my colleagues on the Scientific Committee: Etienne Baulieu, Jack Gorski, Benita Katzenellenbogen, David Toft and James WittJiff, who provided the vision and guidance in formulating an out standing program.



Hormone Receptors


Hormone Receptors
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Author : David Klachko
language : en
Publisher: Springer
Release Date : 2013-12-19

Hormone Receptors written by David Klachko and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-19 with Medical categories.


The Eleventh Midwest Conference on Endocrinology and Metabol ism in September 1975 brought together a number of leading invest igators in the areas of steroid, peptide, acetylcholine, and cate cholamine hormone receptor studies. This book is based upon the reports of investigations into hormone receptor biochemistry and physiology presented at the Conference as well as on the ensuing discussions. However, many of the manuscripts were written after the Conference. Because of this, the reader will find that some literature references and results of i~vestigations are more up to-date than the Conference date would suggest. Perusal of this and previous volumes will attest to the high quality of this annual conference, due primarily to the efforts of the Planning Committee. We also acknowledge the superb efforts of the staff of Conferences and Short Courses for their assistance in organizing the Conference, and Mrs. Linda Bennett for expert sec retarial assistance in the typing of the book. Last, but certain ly not least, we express our appreciation to the various organiza tions that provided the necessary financial assistance. Leonard R. Forte John M. Franz David M. Klachko vii Contents The Receptor Concept: Prejudice, Prediction, and Paradox. ... Oscar M. Hechter Discussion. ... 41 DeGroot, Hechter, Campbell, Freed, Barnawell, Morgan, Siegel Nuclear Receptors for Thyroid Hormone . 45 Leslie J. DeGroot 69 Discussion ...



Molecular Biology Of Steroid And Nuclear Hormone Receptors


Molecular Biology Of Steroid And Nuclear Hormone Receptors
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Author : Leonard Freedman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Molecular Biology Of Steroid And Nuclear Hormone Receptors written by Leonard Freedman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Intracellular Receptors: New Instruments for a Symphony of Signals In the late eighteenth century, it was proposed on theoretical grounds that each of the body's organs, beginning with the brain, must be "a factory and laboratory of a specific humor which it returns to the blood", and that these circulating signals "are indispensable for the life of the whole" (Bordeu 1775). During the nineteenth cen tury, some remarkable physiological experiments revealed the actions of humoral factors that affected the for and function of multiple tissues, organs and organ sys tems within the body (Berthold 1849); much later, the chemical and molecular na ture of some of those factors was determined. Against this deep historical backdrop of the founding studies of intercellular signaling, molecular biology sprang into existence a mere forty years ago, rooted in the revelation of regulable gene expression in bacteria. But contemporaneous with those classical analyses of transcriptional regulation of the lactose operon, the mod em era of signal transduction was inaugurated by the identification of cAMP as a second messenger -- an intracellular mediator of hormonal activation of glycogen catabolism (Sutherland and RaIl 1960). Later in that same decade, it emerged that cAMP is a critical signal not only in metazoans, but even in bacteria, where it serves an analogous function as a critical switch that activates expression of genes re quired for catabolism of complex carbon sources, including those of the lactose operon.



Steroid Receptors In Health And Disease


Steroid Receptors In Health And Disease
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Author : Virinder Moudgil
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Steroid Receptors In Health And Disease written by Virinder Moudgil and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers. Although significant advances have been made in the purification, characterization, immunochemistry and molecular biology of steroid receptors, the precise molecular mechanism of steroid hormone action has remained obscure. This book captures the detailed presentations made at the first conference on Steroid Receptors in Health and Disease held at Meadow Brook Hall, Oakland University in the fall of 1987. The purpose of this international con ference was to facilitate scientific exchange toward a better understand ing of the mode of action of steroid hormones. The scientific sessions consisted of poster presentations and state-of-the-art lectures, the latter of which make up this volume. The first chapter is meant to provide the reader with a more general background of the topics covered in the book, as well as to discuss certain theme-related issues that are either not yet well-established or accepted or are in the stage of infancy. It is hoped that this volume will serve as a useful treatise for students and investigators interested in basic and clinical aspects of biological regulation by steroid hormones. A task of this magnitude could not have been undertaken without the encouragement, advice and continued generous assistance of the members of the scientific committee. I am gratefully indebted to Drs.



Thyroid Hormone Receptors


Thyroid Hormone Receptors
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Author : Aria Baniahmad
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05

Thyroid Hormone Receptors written by Aria Baniahmad and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Medical categories.


A panel of outstanding investigators surveys and explains the major cutting-edge methods used in thryroid receptor (TR) research and explains their practical experimental details. Described in step-by-step detail to ensure robust experimental results, the techniques presented cover a wide variety of key areas, including TR in development and knockout (mouse and Xenopus), transcriptional regulation by TRs in both cell-free systems and in living cells, and TR mutant analysis of patients. Additional methods provide powerful tools for the isolation of TR-regulated protein complexes, for studying the oncogene v-Erba in blood cell differentiation, and for target gene analysis in the brain. Microarray chip methods are also presented for analyzing the organs of transgenic mice to identify target genes in the liver.



Receptors And Hormone Action


Receptors And Hormone Action
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Author : Bert O'Malley
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Receptors And Hormone Action written by Bert O'Malley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Receptors and Hormone Action, Volume 1, provides an overview of the state of knowledge in hormone action. This book describes basic methodologies and model systems used in the exploration of the molecular bases of hormone action. The chapters present not only a rather extensive description of hormone receptors and their properties, but also basic aspects of structure and function of chromatin and membranes, the sites at which hormones and their receptors exert their action. The receptors discussed include soluble cytoplasmic and nuclear receptors for steroid hormones and vitamins, membrane-bound receptors for protein hormones and biogenic amines, and nuclear receptors for thyroid hormones. Receptor types are also covered in view of the large body of literature accumulated on the various functions of these fascinating but elusive molecules. This book is intended for a broad spectrum of readers, including those who have not yet worked in the field as well as those who have considerable expertise in one or another aspect of hormone action.



Receptors And Hormone Action


Receptors And Hormone Action
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Author : Lutz Birnbaumer
language : en
Publisher: Academic Press
Release Date : 2013-10-22

Receptors And Hormone Action written by Lutz Birnbaumer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.


Receptors and Hormone Action, Volume III, is part of a multivolume series that summarizes advances in the field of hormone action. The articles contained in these books are oriented toward a description of basic methodologies and model systems used in the exploration of the molecular bases of hormone action, and are aimed at a broad spectrum of readers including those who have not yet worked in the field as well as those who have considerable expertise in one or another aspect of hormone action. This book opens with a chapter on the physiological properties of the thyroid hormone receptors in the intact animal. This is followed by separate chapters on ß-adrenergic receptors; the study of hormone-receptor interaction by measuring the biological responses induced by the actions of gonadotropins on Leydig cells; chemical and immunochemical properties of hCG and PMSG treated with glycosidases; and binding of follitropin (FSH) to rat testes. Subsequent chapters deal with the control of changes of gonadotropin responsiveness of the granulosa cell during follicular maturation; regulation of prolactin receptors by steroid hormones; and the role of membrane protein phosphorylation in the effects of neurotransmitters.



Molecular Basis Of Sex Hormone Receptor Function


Molecular Basis Of Sex Hormone Receptor Function
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Author : Hinrich Gronemeyer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Molecular Basis Of Sex Hormone Receptor Function written by Hinrich Gronemeyer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.


How sex hormone receptors and all the other members of the nuclear receptor superfamily do such a remarkable job has fascinated scientists for decades. A series of discoveries in the past few years has dramatically enlightened our understanding of the molecular mechanisms that govern nuclear receptor action. The elucidation of the 3D structures of several nuclear receptor ligand binding domains in the presence of agonists or antagonists has provided an allosteric concept of ligand action, and the discovery of a plethora of ligand-dependent protein interactions has linked this transconformation with the ability of nuclear receptors to act as transcriptional activators and repressors and the enzymatic modification of chromatin and factors of the basal transcriptional machinery.