Host Pathogen Interaction During Pneumococcal Infections
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Host Pathogen Interaction During Pneumococcal Infections
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Author : Masaya Yamaguchi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-30
Host Pathogen Interaction During Pneumococcal Infections written by Masaya Yamaguchi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-30 with Science categories.
Streptococcus Pneumoniae
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Author : Jeremy Brown
language : en
Publisher: Academic Press
Release Date : 2015-05-08
Streptococcus Pneumoniae written by Jeremy Brown and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-08 with Science categories.
Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions provides a comprehensive overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology. It presents a state-of-the-art overview of the implications of existing data, along with the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections and how to combat these infections. Users will find a timely update on the topic, as the dramatic increase in antibiotic resistance pneumoniae cases and limitations of the currently available pneumoniae vaccines are creating new concerns on these gram-positive bacteria that are endowed with a high virulence potential, and are the most common etiologic agent of respiratory and life-threatening invasive diseases. - Provides an updated overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology - Helps strengthen interdisciplinary networking and the focus of scientific resources by targeting epidemiology, vaccines, genetics, antibiotic resistance, clonal dissemination, Streptococcus pneumoniae biology, functional genomics, inflammasome, biomarkers, and more - Multi-authored by leaders in the field who present a state-of-the-art overview of what the implications are of existing data, and the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections - Supports combinatory networking in order to find new solutions in clinical therapies - Reflects the most topical pneumococcal research trends
Cell Signaling In Host Pathogen Interactions The Host Point Of View
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Author : Diana Bahia
language : en
Publisher: Frontiers Media SA
Release Date : 2018-03-23
Cell Signaling In Host Pathogen Interactions The Host Point Of View written by Diana Bahia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-23 with categories.
The ability of pathogens, such as parasites, bacteria, fungi and viruses to invade, persist and adapt in both invertebrate and vertebrate hosts is multifactorial and depends on both pathogen and host fitness. Communication between a pathogen and its host relies on a wide and dynamic array of molecular interactions. Through this constant communication most pathogens evolved to be relatively benign, whereas killing of its host by a pathogen represents a failure to adapt. Pathogens are lethal to their host when their interaction has not been long enough for adaptation. Evolution has selected conserved immune receptors that recognize signature patterns of pathogens as non-self elements and initiate host innate responses aimed at eradicating infection. Conversely, pathogens evolved mechanisms to evade immune recognition and subvert cytokine secretion in order to survive, replicate and cause disease. The cell signaling machinery is a critical component of the immune system that relays information from the receptors to the nucleus where transcription of key immune genes is activated. Host cells have developed signal transduction systems to maintain homeostasis with pathogens. Most cellular processes and cell signaling pathways are tightly regulated by protein phosphorylation in which protein kinases are key protagonists. Pathogens have developed multiple mechanisms to subvert important signal transduction pathways such as the mitogen activated protein kinase (MAPK) and the nuclear factor kB (NF-kB) pathways. Pathogens also secrete effectors that manipulate actin cytoskeleton and its regulators, hijack cell cycle machinery and alter vesicular trafficking. This research topic focuses on the cellular signaling mechanisms that are essential for host immunity and their subversion by pathogens.
Acute Exacerbations Of Pulmonary Diseases
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Author : Pierre-Régis Burgel
language : en
Publisher: European Respiratory Society
Release Date : 2017-09-01
Acute Exacerbations Of Pulmonary Diseases written by Pierre-Régis Burgel and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-01 with Medical categories.
The field of acute exacerbations in chronic respiratory disease is challenging: definitions of acute exacerbations differ amongst the diseases and their severity has proven difficult to define. The Guest Editors of this Monograph tackle this challenging area by bringing together articles from internationally recognised experts in the field of acute exacerbations in chronic lung diseases. The book is separated into three sections: the first considers the definition, severity and consequences of exacerbations in each disease; the second looks at exacerbation triggers; and the third discusses the treatment and prevention of exacerbations using pharmacological and non-pharmacological interventions. The book’s structure allows comparisons between the definitions, short- and long-term consequences, triggers and therapeutic management of different respiratory diseases. It serves as a complete reference that raises awareness about the importance of acute exacerbations in patients with chronic lung diseases.
Host Pathogen Interactions In Streptococcal Diseases
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Author : G Singh Chhatwal
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-07-08
Host Pathogen Interactions In Streptococcal Diseases written by G Singh Chhatwal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Medical categories.
Streptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases.
Hot Topics In Infection And Immunity In Children Vi
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Author : Adam Finn
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10
Hot Topics In Infection And Immunity In Children Vi written by Adam Finn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.
Course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections. Each of the chapters in this book is based on a lecture given at the sixth "Infection and Immunity in Children" course, held at the end of June 2008 at Keble College, Oxford. Thus, it is the sixth book in a series that provides succinct and readable updates on just about every aspect of the discipline of Pediatric Infectious Diseases.
Perforins And Cholesterol Dependent Cytolysins In Immunity And Pathogenesis
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Author : George P. Munson
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-25
Perforins And Cholesterol Dependent Cytolysins In Immunity And Pathogenesis written by George P. Munson and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-25 with Science categories.
Host Pathogen Interaction In Central Nervous System Infection
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Author : Federico Iovino
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-04
Host Pathogen Interaction In Central Nervous System Infection written by Federico Iovino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-04 with Science categories.
Transmission Colonization And Molecular Pathogenesis Of Pneumococcus
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Author : Jorge Eugenio Vidal
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-23
Transmission Colonization And Molecular Pathogenesis Of Pneumococcus written by Jorge Eugenio Vidal and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-23 with Science categories.
Applications Of Rna Seq In Biology And Medicine
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Author : Irina Vlasova-St. Louis
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-10-13
Applications Of Rna Seq In Biology And Medicine written by Irina Vlasova-St. Louis and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-13 with Science categories.
This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation.