Immunodominance
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Immunodominance
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Author : Jeffrey A. Frelinger
language : en
Publisher: John Wiley & Sons
Release Date : 2006-05-12
Immunodominance written by Jeffrey A. Frelinger and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-12 with Medical categories.
This very first handbook on the topic summarizes the current concepts and brings together in one volume the critical arguments concerning the mechanisms relevant to immunodominance. In invited chapters written by the leaders in the field, the mechanisms whereby the immune system chooses the parts of a recognized pathogen in order to start the immune response are explained and the variety of biologic processes are identified that contribute to that choice. From the contents: * Mechanics of antigen processing * Proteosome specificity and immuno-proteosomes * Effect of the T cell repertoire on dominance * Effects of pathogens on the immune response
The Cytotoxic T Cell Response To Flavivirus Infection
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Author : Matthias Regner
language : en
Publisher:
Release Date : 2000
The Cytotoxic T Cell Response To Flavivirus Infection written by Matthias Regner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Flaviviruses categories.
The Role Of Antigen Processing In Determinant Selection And Immunodominance
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Author : Hongkui Deng
language : en
Publisher:
Release Date : 1995
The Role Of Antigen Processing In Determinant Selection And Immunodominance written by Hongkui Deng and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.
Current Challenges In Vaccinology
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Author : Ursula Wiedermann
language : en
Publisher: Frontiers Media SA
Release Date : 2021-02-22
Current Challenges In Vaccinology written by Ursula Wiedermann and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-22 with Medical categories.
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS).
The New Paradigm Of Immunity To Tuberculosis
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Author : Maziar Divangahi
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-12
The New Paradigm Of Immunity To Tuberculosis written by Maziar Divangahi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Medical categories.
This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed. The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection. Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.
Vaccine Design
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Author : Sunil Thomas
language : en
Publisher: Springer Nature
Release Date : 2021-12-16
Vaccine Design written by Sunil Thomas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-16 with Science categories.
This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field.
Statistical Mechanics Of Cellular Systems And Processes
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Author : Muhammad H. Zaman
language : en
Publisher: Cambridge University Press
Release Date : 2009-03-26
Statistical Mechanics Of Cellular Systems And Processes written by Muhammad H. Zaman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-26 with Science categories.
Cells are complex objects, representing a multitude of structures and processes. In order to understand the organization, interaction and hierarchy of these structures and processes, a quantitative understanding is absolutely critical. Traditionally, statistical mechanics-based treatment of biological systems has focused on the molecular level, with larger systems being ignored. This book integrates understanding from the molecular to the cellular and multi-cellular level in a quantitative framework that will benefit a wide audience engaged in biological, biochemical, biophysical and clinical research. It will build new bridges of quantitative understanding that link fundamental physical principles governing cellular structure and function with implications in clinical and biomedical contexts.
Advances In Cancer Research
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Author : George F. Vande Woude
language : en
Publisher: Elsevier
Release Date : 2011-07-29
Advances In Cancer Research written by George F. Vande Woude and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-29 with Science categories.
The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics including NY-ESO-1: review of an immunogenic tumor antigen; Order, disorder, death: lessons from a superorganism; Control of differentiation in progression of epithelial tumors; Cancer vaccines: preclinical studies and novel strategies; Clinical results of vaccine therapy for cancer: learning from history for improving the future; Immunodominance and immunodomination: critical factors in developing effective CD8+ T-cell based cancer vaccines; NK cell receptors as tools in cancer immunotherapy; Innate immune recognition and suppression of tumors; Inhibitors of the HSP90 molecular chaperone: current status.
Minor Histocompatibility Antigens
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Author : Derry Roopenian
language : en
Publisher: CRC Press
Release Date : 1999-08-01
Minor Histocompatibility Antigens written by Derry Roopenian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-08-01 with Science categories.
With the widespread application of solid tissue and bone marrow transplantation as a treatment for an array of life threatening disorders, there is a pressing need for clinicians and experimentalists to understand the basis of immunological rejection of tissue transplants. While much previous work focuses on characterization of antigens encoded by
Experimental And Applied Immunotherapy
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Author : Jeffrey Medin
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-03
Experimental And Applied Immunotherapy written by Jeffrey Medin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-03 with Medical categories.
Immunotherapy is now recognized as an essential component of treatment for a wide variety of cancers. It is an interdisciplinary field that is critically dependent upon an improved understanding of a vast network of cross-regulatory cellular populations and a diversity of molecular effectors; it is a leading example of translational medicine with a favorable concept-to-clinical-trial timeframe of just a few years. There are many established immunotherapies already in existence, but there are exciting new cancer immunotherapies just on the horizon, which are likely to be more potent, less toxic and more cost effective than many therapies currently in use. Experimental and Applied Immunotherapy is a state-of-the-art text offering a roadmap leading to the creation of these future cancer-fighting immunotherapies. It includes essays by leading researchers that cover a wide variety of topics including T cell and non-T cell therapy, monoclonal antibody therapy, dendritic cell-based cancer vaccines, mesenchymal stromal cells, negative regulators in cancer immunology and immunotherapy, non-cellular aspects of cancer immunotherapy, the combining of cancer vaccines with conventional therapies, the combining of oncolytic viruses with cancer immunotherapy, transplantation, and more. The field of immunotherapy holds great promise that will soon come to fruition if creative investigators can bridge seemingly disparate disciplines, such as T cell therapy, gene therapy, and transplantation therapy. This text is a vital tool in the building of that bridge.