In Vitro Methods In Toxicology
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In Vitro Methods In Pharmaceutical Research
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Author : Jose V. Castell
language : en
Publisher: Elsevier
Release Date : 1996-10-04
In Vitro Methods In Pharmaceutical Research written by Jose V. Castell and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-10-04 with Medical categories.
In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies. - Meets the continuing demand for information in this field - Compares In Vitro techniques with other methods - Describes cell-culture methods used to investigate toxicity in cells derived from different organs - Includes contributions by leading experts in the field
In Vitro Methods In Toxicology
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Author : C. K. Atterwill
language : en
Publisher: Cambridge University Press
Release Date : 1987-10-22
In Vitro Methods In Toxicology written by C. K. Atterwill and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-10-22 with Medical categories.
The volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists.
In Vitro Methods In Developmental Toxicology
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Author : Gary L. Kimmel
language : en
Publisher: CRC Press
Release Date : 2019-06-04
In Vitro Methods In Developmental Toxicology written by Gary L. Kimmel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.
First Published in 1990, this text brings together the work of several investigators who used in vitro techniques to probe the nature of embryonic cell response to a diverse group of chemical agents. It focuses on the approaches, limitations, usefulness and applicability of defining mechanisms underlying altered development. This work includes discussions on pharmacodynamic principles and placental transfer mechanisms. It also examines the potential for in vitro systems to serve as an adjunct to the risk assessment process. Ideal for both the layman and the expert in this area, this volume provides a general understanding of the types of approaches that can be used and specific approaches in investigating altered development.
Principles Of Toxicology Testing
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Author : Frank A Barile
language : en
Publisher: CRC Press
Release Date : 2013-04-02
Principles Of Toxicology Testing written by Frank A Barile and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-02 with Medical categories.
Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, includin
Cell Culture Methods For In Vitro Toxicology
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Author : G. Stacey
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Cell Culture Methods For In Vitro Toxicology written by G. Stacey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Fundamental chapters deal with the general biology of cytotoxicity and cell immortalisation these are key issues for in vitro systems addressing the `3Rs' principle. Up-to-date overviews deal with the use of cells from liver, brain and intestine. In addition, biochemical analysis of cell responses, biotransformation pathways in cells and recombinant approaches to the early detection of cell stress are also covered in detail. Prominent features of in vitro technologies also include regulation, biosafety and standardisation. Dedicated chapters deal with these issues in a practical way in order to lead the reader to the right source of information. This book provides an up-to-date, informative and practical review of cell culture methods for in vitro toxicology. It will be of equal benefit to students and experienced toxicologists with little experience of in vitro cell culture.
Hayes Principles And Methods Of Toxicology
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Author : A. Wallace Hayes
language : en
Publisher: CRC Press
Release Date : 2014-10-10
Hayes Principles And Methods Of Toxicology written by A. Wallace Hayes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Medical categories.
Hayes' Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chap
In Vitro Methods In Aquatic Ecotoxicology
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Author : Carmel Mothersill
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-08-14
In Vitro Methods In Aquatic Ecotoxicology written by Carmel Mothersill and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-14 with Medical categories.
This book, the first of its kind in this subject area, will focus on in vitro approaches to the study of the toxicology of polluting agents (including heavy metals, radionuclides, micro-organics, estrogenic compounds, and complex mixtures) in the aquatic environment. The importance of in vitro methods is that they allow standardised techniques to be developed and validated for substance and species specific experiments in a controlled way. Also, they allow mechanistic studies without the problems of individual variation between animals and environmental stress.
Principles And Methods Of Toxicology
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Author : A. Wallace Hayes
language : en
Publisher: CRC Press
Release Date : 2007-09-25
Principles And Methods Of Toxicology written by A. Wallace Hayes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-25 with Medical categories.
Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanis
In Vitro Methods In Toxicity Testing And Biomedical Research
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Author :
language : en
Publisher:
Release Date : 1990
In Vitro Methods In Toxicity Testing And Biomedical Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Animal experimentation categories.
In Vitro Toxicology
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Author : Alok Dhawan
language : en
Publisher: Academic Press
Release Date : 2017-11-13
In Vitro Toxicology written by Alok Dhawan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-13 with Science categories.
In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. - Discusses new techniques and protocols in a clear and concise manner - includes examinations of nanotoxicity, genotoxicity and carcinogenicity - Explains practical laboratory methods and the theories behind in vitro testing