Insights In Rna Networks And Biology
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Insights In Rna Networks And Biology
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Author : André P. Gerber
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-13
Insights In Rna Networks And Biology written by André P. Gerber and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-13 with Science categories.
We are now entering the third decade of the 21st Century, and recent, major achievements by scientists have led to major advancements in the fast-growing field of RNA Networks and Biology. This Research Topic aims to highlight the latest advancements in RNA research, and also reflect on the future of the field – what are the next expected breakthroughs and advancements? The Research Topic will collect articles from the members of our accomplished Editorial Board and is led by our Chief Editors, André Gerber and Gian Tartaglia. We are excited to receive brief, forward-looking contributions that describe the state of the art, outlining recent developments and major accomplishments that have been achieved and that need to occur to move the field forward. Authors are encouraged to identify the greatest challenges in the sub-disciplines, and how to address those challenges.
Rna Infrastructure And Networks
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Author : Lesley J. Collins
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-15
Rna Infrastructure And Networks written by Lesley J. Collins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-15 with Medical categories.
RNAs form complexes with proteins and other RNAs. The RNA‐infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell‐wide network. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA‐based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA‐based mechanisms that connect in the RNA infrastructure.
Insights In Systems Biology Research
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Author : Gary An
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-10
Insights In Systems Biology Research written by Gary An and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-10 with Science categories.
Summary of Topic: This collection represents an interdisciplinary exploration of systems biology and systems medicine, integrating advanced methodologies from computational modeling, deep neural networks, and multiomics to improve understanding and treatment of human diseases and biological mechanisms. Emphasis is placed on cutting-edge technologies, including deep learning for statistical inference from gene expression data and noncoding genetic variants, quantitative systems pharmacology for virtual patient generation, and semi-mechanistic modeling applied to novel therapies such as CAR T-cell interventions. The articles further highlight disease modeling across various scales, exemplified through multi-scale simulation frameworks applied to complex conditions such as COVID-19 long-term sequelae, rheumatoid arthritis, epilepsy, and tuberculosis. Additionally, the importance of modularity in biological networks, developments in functional annotation of microbial transporters, and new approaches towards bioengineered bacterial consortia through molecular communication are discussed. This collection informs us of the ongoing efforts to harness computational power and biological insights to advance personalized medicine, improve therapeutic strategies, and deepen our understanding of complex biological phenomena. ----- Systems Biology has undergone significant transformations due to the pioneering efforts of researchers worldwide. The discipline now spans several subfields, such as Neuroscience, Genetics and Genomics, Medicine, among others, each advancing the field in unique ways through innovative technologies and insightful discoveries. This evolution is celebrated in a curated collection by Frontiers in Systems Biology, which aims to highlight the state-of-the-art developments and set the stage for future inquiries and applications in the field. This collection actively showcases the overlap of technology with theoretical advancements, creating a broad framework from which new methodologies and strategies are born. This Research Topic aims to provide an overview of the most recent progress in Systems Biology. It seeks to outline the impacts that the integration of disparate biological research areas can have in solving complex biological problems and advancing human health. Without losing sight of the past achievements, the goal is to explore the potential of future advancements, addressing the challenges that remain at the forefront of this vibrant field. The scope of this Research Topic is broadly defined yet focused on areas where significant innovative strides have been made. We welcome contributions that emphasize: - Integrative approaches in Systems Neuroscience - Contemporary breakthroughs in Genetics and Genomics - The use of Multiscale Mechanistic Modelling to represent biological interfaces - Bridging gaps between experimental and computational biology in Translational Systems Biology - Enhancing methodologies in Data and Model Integration This collection welcomes contributions from Editorial Board Members or those referred by a board member, reflecting on current developments and plotting pathways for upcoming research endeavors. Authors are encouraged to engage critically with their fields, identifying current challenges and proposing novel solutions to advance the understanding of complex systems within biology.
Molecular Biology
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Author : Jordanka Zlatanova
language : en
Publisher: Taylor & Francis
Release Date : 2023-04-21
Molecular Biology written by Jordanka Zlatanova and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-21 with Science categories.
Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous, yet still concise, summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system, Coronaviruses – structure, genome, vaccine and drug development, and newly recognized mechanisms for transcription termination. The text is written for advanced undergraduate or graduate-level courses in molecular biology. Key Features Highlights the experimental basis of important discoveries in molecular biology Thoroughly updated with new information on gene editing tools, viruses, and transcription mechanisms, termination and antisense Provides learning objectives for each chapter Includes a list of relevant videos from the Internet about the topics covered in the chapter
Novel Insights In Rna Modifications From Basic To Translational Research
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Author : Huilin Huang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-06
Novel Insights In Rna Modifications From Basic To Translational Research written by Huilin Huang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-06 with Science categories.
Rna Bioinformatics
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Author : Ernesto Picardi
language : en
Publisher: Humana
Release Date : 2016-09-24
Rna Bioinformatics written by Ernesto Picardi and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-24 with Science categories.
This volume provides an overview of RNA bioinformatics methodologies, including basic strategies to predict secondary and tertiary structures, and novel algorithms based on massive RNA sequencing. Interest in RNA bioinformatics has rapidly increased thanks to the recent high-throughput sequencing technologies allowing scientists to investigate complete transcriptomes at single nucleotide resolution. Adopting advanced computational technics, scientists are now able to conduct more in-depth studies and present them to you in this book. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and equipment, step-by-step, readily reproducible bioinformatics protocols, and key tips to avoid known pitfalls. Authoritative and practical, RNA Bioinformatics seeks to aid scientists in the further study of bioinformatics and computational biology of RNA.
Applications Of Rna Seq In Biology And Medicine
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Author : Irina Vlasova-St. Louis
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-10-13
Applications Of Rna Seq In Biology And Medicine written by Irina Vlasova-St. Louis and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-13 with Science categories.
This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation.
Analyzing Network Data In Biology And Medicine
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Author : Nataša Pržulj
language : en
Publisher: Cambridge University Press
Release Date : 2019-03-28
Analyzing Network Data In Biology And Medicine written by Nataša Pržulj and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-28 with Language Arts & Disciplines categories.
Introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, using real-world biological and medical examples.
Plant Rna Biology
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Author : Dóra Szakonyi
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-18
Plant Rna Biology written by Dóra Szakonyi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-18 with categories.
Discoveries from the past decades revealed that RNA molecules are much more than inert intermediates between the coding DNA sequences and their functional products, proteins. Today, RNAs are recognized as active regulatory molecules influencing gene expression, chromatin organization and genome stability, thus impacting all aspects of plant life including development, growth, reproduction and stress tolerance. Innovations in methodologies, the expanding application of next-generation sequencing technologies, and the creation of public datasets and databases have exposed a new universe of RNA-based mechanisms and led to the discovery of new families of non-coding RNAs, uncovered the large extent of alternative splicing events, and highlighted the potential roles of RNA modifications and RNA secondary structures. Furthermore, considerable advances have been made in identifying RNA-binding and processing factors involved in the synthesis and maturation of different forms of RNA molecules as well as in RNA processing, biochemical modifications or degradation. This Research Topic showcases the broad biological significance of RNAs in plant systems and contains eight original research articles, one review and four mini-reviews, covering various RNA-based mechanisms in higher plants. Emerging new technologies and novel multidisciplinary approaches are empowering the scientific community and will expectedly bring novel insights into our understanding of the mechanisms through which RNA is regulated and regulates biological processes in plant cells.
New Insights Of Immune Cells In Cardiovascular And Metabolic Disorders
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Author : Yingmei Feng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-26
New Insights Of Immune Cells In Cardiovascular And Metabolic Disorders written by Yingmei Feng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-26 with Medical categories.