Rna Bioinformatics


Rna Bioinformatics
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Rna Bioinformatics


Rna Bioinformatics
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Author : Ernesto Picardi
language : en
Publisher:
Release Date : 2021

Rna Bioinformatics written by Ernesto Picardi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Biochemistry categories.


This detailed book aims to provide an overview of novel bioinformatics resources for exploring diverse aspects of RNA biology. This edition focuses on methods dealing with non-coding RNA (miRNAs, circRNAs or lncRNAs), RNA modifications (m6A or RNA editing), single cell RNA-seq and statistical models to handle count data from RNA-seq experiments. The book also includes chapters based on the classical RNA bioinformatics methods, such as those for deciphering secondary and tertiary RNA structures; however, they are revised to take into account deep sequencing data. Finally, chapters describing methods to analyze RNA sequencing data from emerging third generation sequencing technologies that could provide interesting insights into the transcriptional process and its regulation are also included. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of expert implementation advice that encourages quality results. Comprehensive and up-to-date, RNA Bioinformatics, Second Edition serves as an ideal guide for researchers digging ever-deeper into the depths of the study of RNAs. The chapter 'RNA-Seq Data Analysis in Galaxy' is open access under a CC BY 4.0 license.



Bioinformatics And Rna


Bioinformatics And Rna
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Author : Dolly Sharma
language : en
Publisher: CRC Press
Release Date : 2021-08-17

Bioinformatics And Rna written by Dolly Sharma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Mathematics categories.


This book offers a unique balance between a basic introductory knowledge of bioinformatics and a detailed study of algorithmic techniques. Bioinformatics and RNA: A Practice-Based Approach is a complete guide on the fundamental concepts, applications, algorithms, protocols, new trends, challenges, and research results in the area of bioinformatics and RNA. The book offers a broad introduction to the explosively growing new discipline of bioinformatics. It covers theoretical topics along with computational algorithms. It explores RNA bioinformatics, which contribute to therapeutics and drug discovery. Implementation of algorithms in a DotNet Framework with code and complete insight on the state-of-the-art and recent advancements are presented in detail. The book targets both novice readers as well as practitioners in the field. FEATURES Offers a broad introduction to the explosively growing new discipline of bioinformatics Covers theoretical topics and computational algorithms Explores RNA bioinformatics to unleash the potential from therapeutics to drug discovery Discusses implementation of algorithms in DotNet Frameworks with code Presents insights into the state of the art and recent advancements in bioinformatics The book is useful to undergraduate students with engineering, science, mathematics, or biology backgrounds. Researchers will be equally interested.



Rna Sequence Structure And Function Computational And Bioinformatic Methods


Rna Sequence Structure And Function Computational And Bioinformatic Methods
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Author : Jan Gorodkin
language : en
Publisher: Humana Press
Release Date : 2014-03-18

Rna Sequence Structure And Function Computational And Bioinformatic Methods written by Jan Gorodkin and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-18 with Science categories.


The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results. Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.



Computational Epitranscriptomics Bioinformatic Approaches For The Analysis Of Rna Modifications


Computational Epitranscriptomics Bioinformatic Approaches For The Analysis Of Rna Modifications
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Author : Mattia Pelizzola
language : en
Publisher: Frontiers Media SA
Release Date : 2021-02-02

Computational Epitranscriptomics Bioinformatic Approaches For The Analysis Of Rna Modifications written by Mattia Pelizzola and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-02 with Science categories.




Rna Seq Data Analysis


Rna Seq Data Analysis
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Author : Eija Korpelainen
language : en
Publisher: CRC Press
Release Date : 2014-09-19

Rna Seq Data Analysis written by Eija Korpelainen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-19 with Mathematics categories.


The State of the Art in Transcriptome AnalysisRNA sequencing (RNA-seq) data offers unprecedented information about the transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. RNA-seq Data Analysis: A Practical Approach enables researchers to examine differential expression at gene, exon, and transcript le



Computational Non Coding Rna Biology


Computational Non Coding Rna Biology
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Author : Yun Zheng
language : en
Publisher: Academic Press
Release Date : 2018-09-14

Computational Non Coding Rna Biology written by Yun Zheng and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-14 with Science categories.


Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules. Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis. Presents a comprehensive resource of computational methods for the identification and quantification of non-coding RNAs Introduces 23 practical computational pipelines for various topics of non-coding RNAs Provides a guide to assist biologists and other researchers dealing with complex datasets Introduces basic computational methods and provides guidelines for their replication by researchers Offers a solution to researchers approaching large and complex sequencing datasets



Non Coding Rnas In Complex Diseases


Non Coding Rnas In Complex Diseases
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Author : Xia Li
language : en
Publisher: Springer
Release Date : 2018-09-06

Non Coding Rnas In Complex Diseases written by Xia Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-06 with Science categories.


This book offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from a view of bioinformatics. It conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional prediction, to their roles in diseases. Computational methods used to investigate uncharacterised ncRNAs in diseases are mainly summarized in seven aspects: DNA variation of ncRNAs in diseases, prioritization of disease-related ncRNAs, dysregulation epigenetic factors that regulate ncRNA misexpression (DNA methylation and histone-modification), complex crosstalk across ncRNAs, ncRNAs acted as competing regulators to mediate the expression of protein-coding genes, non-coding RNAs mediated risk pathways,and their contributions to drug target predictions. The generally used data resources of ncRNAs are also listed in the end. This book provides important information on the current progress in the fast-moving fields of bioinformatics for regulatory ncRNAs. It provides a timely and useful reference for computational biologists, specifically with RNA interests, and other related areas. Prof. Xia Li is a Professor and the Dean of College of Bioinformatics Science and Technology, Harbin Medical University, China. Dr. Yun Xiao, Dr. Juan Xu, Dr. Shangwei Ning and Dr. Yunpeng Zhang are from College of Bioinformatics Science and Technology, Harbin Medical University, China.



Rna Bioinformatics


Rna Bioinformatics
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Author : Ernesto Picardi
language : en
Publisher: Humana
Release Date : 2016-09-24

Rna Bioinformatics written by Ernesto Picardi and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-24 with Science categories.


This volume provides an overview of RNA bioinformatics methodologies, including basic strategies to predict secondary and tertiary structures, and novel algorithms based on massive RNA sequencing. Interest in RNA bioinformatics has rapidly increased thanks to the recent high-throughput sequencing technologies allowing scientists to investigate complete transcriptomes at single nucleotide resolution. Adopting advanced computational technics, scientists are now able to conduct more in-depth studies and present them to you in this book. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and equipment, step-by-step, readily reproducible bioinformatics protocols, and key tips to avoid known pitfalls. Authoritative and practical, RNA Bioinformatics seeks to aid scientists in the further study of bioinformatics and computational biology of RNA.



Bioinformatics


Bioinformatics
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Author : Andrzej Polanski
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-19

Bioinformatics written by Andrzej Polanski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-19 with Computers categories.


This textbook presents mathematical models in bioinformatics and describes biological problems that inspire the computer science tools used to manage the enormous data sets involved. The first part of the book covers mathematical and computational methods, with practical applications presented in the second part. The mathematical presentation avoids unnecessary formalism, while remaining clear and precise. The book closes with a thorough bibliography, reaching from classic research results to very recent findings. This volume is suited for a senior undergraduate or graduate course on bioinformatics, with a strong focus on mathematical and computer science background.



Multiple Aspects Of Dna And Rna From Biophysics To Bioinformatics


Multiple Aspects Of Dna And Rna From Biophysics To Bioinformatics
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Author : Didier Chatenay
language : en
Publisher: Gulf Professional Publishing
Release Date : 2005-12-19

Multiple Aspects Of Dna And Rna From Biophysics To Bioinformatics written by Didier Chatenay and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-19 with Computers categories.


Dedicated to the multiple aspects, that is, biological, physical and computational of DNA and RNA molecules, this book is divided into three main sections. It is intended to be a reference for advanced graduate students or young researchers to acquire an interdisciplinary understanding of the multiple aspects of DNA and RNA.