Rna Structure Prediction
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Rna 3d Structure Analysis And Prediction
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Author : Neocles Leontis
language : en
Publisher: Springer
Release Date : 2014-06-11
Rna 3d Structure Analysis And Prediction written by Neocles Leontis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-11 with Science categories.
With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone. This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.
Rna Biochemistry And Biotechnology
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Author : Jan Barciszewski
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-08-31
Rna Biochemistry And Biotechnology written by Jan Barciszewski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-08-31 with Science categories.
RNA Biochemistry and Biotechnology describes various aspects of nucleic acid and protein structure, mainly RNA structure and proteins, interacting with specific RNA species. Papers deal with DNA protein interactions, telomerase, aminoacyl-tRNA synthetases, elongation factor Tu, DNA repair, RNA structure, NMR technology, RNA aptamer interaction of biological macromolecules with metal ions. Two papers deal with theoretical aspects of RNA structure production and computer modelling. Many papers describe the possibility of commercial application of RNA biotechnology. One article discusses the impact of direct democracy on basic science supporting biotechnology. Readership: Advanced graduate students, Ph.D. students and young scientists as well as specialists in the field.
Rna Sequence Structure And Function Computational And Bioinformatic Methods
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Author : Jan Gorodkin
language : en
Publisher: Humana
Release Date : 2014-03-18
Rna Sequence Structure And Function Computational And Bioinformatic Methods written by Jan Gorodkin and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-18 with Science categories.
The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results. Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.
Rna Structure Prediction
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Author : Risa Karakida Kawaguchi
language : en
Publisher: Springer Nature
Release Date : 2023-01-27
Rna Structure Prediction written by Risa Karakida Kawaguchi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-27 with Science categories.
This book explores recent progress in RNA secondary, tertiary structure prediction, and its application from an expansive point of view. Because of advancements in experimental protocols and devices, the integration of new types of data as well as new analysis techniques is necessary, and this volume discusses additional topics that are closely related to RNA structure prediction, such as the detection of structure-disrupting mutations, high-throughput structure analysis, and 3D structure design. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to quality research results. Authoritative and practical, RNA Structure Prediction serves as a valuable guide for both experimental and computational RNA researchers.
Rna Structure And Folding
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Author : Dagmar Klostermeier
language : en
Publisher: Walter de Gruyter
Release Date : 2013-10-14
Rna Structure And Folding written by Dagmar Klostermeier and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-14 with Science categories.
While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples.
Bioinformatics In Rice Research
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Author : Manoj Kumar Gupta
language : en
Publisher: Springer Nature
Release Date : 2021-09-24
Bioinformatics In Rice Research written by Manoj Kumar Gupta and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-24 with Science categories.
This book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment. In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions, and molecular markers, including SNP and microsatellites, in the contexts of rice breeding and genetics. Lastly, it explores various tools that are used to identify and characterize non-coding RNA in rice and their potential role in rice research.
Non Protein Coding Rnas
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Author : Nils Walter
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-11-18
Non Protein Coding Rnas written by Nils Walter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-18 with Science categories.
The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows “RNA” Nobels for splicing and RNA catalysis, highlights just one class of recently discovered non-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life. The resulting understanding of the physical and chemical processes at the molecular level is critical to our ability to harness RNA for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.
Rna Bioinformatics
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Author : Ernesto Picardi
language : en
Publisher: Humana
Release Date : 2016-09-24
Rna Bioinformatics written by Ernesto Picardi and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-24 with Science categories.
This volume provides an overview of RNA bioinformatics methodologies, including basic strategies to predict secondary and tertiary structures, and novel algorithms based on massive RNA sequencing. Interest in RNA bioinformatics has rapidly increased thanks to the recent high-throughput sequencing technologies allowing scientists to investigate complete transcriptomes at single nucleotide resolution. Adopting advanced computational technics, scientists are now able to conduct more in-depth studies and present them to you in this book. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and equipment, step-by-step, readily reproducible bioinformatics protocols, and key tips to avoid known pitfalls. Authoritative and practical, RNA Bioinformatics seeks to aid scientists in the further study of bioinformatics and computational biology of RNA.
Intelligent Computing Theories And Application
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Author : De-Shuang Huang
language : en
Publisher: Springer
Release Date : 2018-08-08
Intelligent Computing Theories And Application written by De-Shuang Huang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-08 with Computers categories.
This two-volume set LNCS 10954 and LNCS 10955 constitutes - in conjunction with the volume LNAI 10956 - the refereed proceedings of the 14th International Conference on Intelligent Computing, ICIC 2018, held in Wuhan, China, in August 2018. The 275 full papers and 72 short papers of the three proceedings volumes were carefully reviewed and selected from 632 submissions. The papers are organized in topical sections such as Neural Networks.- Pattern Recognition.- Image Processing.- Intelligent Computing in Robotics.- Intelligent Control and Automation.- Intelligent Data Analysis and Prediction.- Fuzzy Theory and Algorithms.- Supervised Learning.- Unsupervised Learning.- Kernel Methods and Supporting Vector Machines.- Knowledge Discovery and Data Mining.- Natural Language Processing and Computational Linguistics.- Gene Expression Array Analysis.- Systems Biology.- Computational Genomics.- Computational Proteomics.- Gene Regulation Modeling and Analysis.- Protein-Protein Interaction Prediction.- Next-Gen Sequencing and Metagenomics.- Structure Prediction and Folding.- Evolutionary Optimization for Scheduling.- High-Throughput Biomedical Data Integration and Mining.- Machine Learning Algorithms and Applications.- Heuristic Optimization Algorithms for Real-World Applications.- Evolutionary Multi-Objective Optimization and Its Applications.- Swarm Evolutionary Algorithms for Scheduling and Combinatorial.- Optimization.- Swarm Intelligence and Applications in Combinatorial Optimization.- Advances in Metaheuristic Optimization Algorithm.- Advances in Image Processing and Pattern Recognition Techniques.- AI in Biomedicine.- Bioinformatics.- Biometrics Recognition.- Information Security.- Virtual Reality and Human-Computer Interaction.- Healthcare Informatics Theory and Methods.- Intelligent Computing in Computer Vision.- Intelligent Agent and Web Applications.- Reinforcement Learning.- Machine Learning.- Modeling, Simulation, and Optimization of Biological Systems.- Biomedical Data Modeling and Mining.- Cheminformatics.- Intelligent Computing in Computational Biology.- Protein Structure and Function Prediction.- Biomarker Discovery.- Hybrid Computational Intelligence: Theory and Application in Bioinformatics, Computational Biology and Systems Biology.- IoT and Smart Data.- Intelligent Systems and Applications for Bioengineering.- Evolutionary Optimization: Foundations and Its Applications to Intelligent Data Analytics.- Protein and Gene Bioinformatics: Analysis, Algorithms and Applications.
Rna Folding
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Author : Christina Waldsich
language : en
Publisher: Humana
Release Date : 2016-08-23
Rna Folding written by Christina Waldsich and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.
Focusing on in vitro and intracellular RNA structure formation, RNA Folding: Methods and Protocols provides a comprehensive collection of experimental protocols which are suitable to dissect RNA folding pathways and to characterize the structure of RNA folding intermediates at nucleotide or even atomic resolution. The presented techniques include powerful tools with a long tradition in RNA research as well as more advanced, novel methods, thus the methods span multiple disciplines, including molecular biology, biochemistry, biophysics, and computational biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, RNA Folding: Methods and Protocols serves as a vital reference for researchers attempting to gain insights into the secrets of this astounding macromolecule.