Interferons And Their Applications
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Interferons And Their Applications
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Author : P.E. Came
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Interferons And Their Applications written by P.E. Came and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Today, the basic mood of researchers and clinical investigators, both at the center and on the periphery of interferon studies, is optimistic regarding the future of interferons as therapeutic substances. Many also feel these polypeptides will prove invaluable probes in unraveling certain fundamental biochemical processes which control the life cycle and developmental pattern of many human cells. In contrast, only a year or two ago, this optimism had given way to an attitude almost of disenchantment as public and scientific expectations were raised steeply, then rapidly waned, as it turns out, prematurely. Both the mUltiple actions of interferons (a virtual cascade of biochemical reactions may be induced, as documented herein) and the high visibility of interferon research provided by the millions of dollars invested both by national health agencies and by multinational pharmaceutical companies, contributed to an upsweep in public attention to drug development probably unprecedented in this century. Virtually every oncologist, it would seem, was plagued by requests for the experimental agent, although they already had therapies of more proven value. As recently as 1980, even though interferon had achieved success against certain cancers and certain viral diseases, the variability in clinical results was seemingly ever present and little evidence emerged to suggest interferons could cure advanced diseases. Why then the resurgence of an optimistic mood? There are almost always many elements which contribute to happiness, and this is certainly true of the broad frontier of interferon and its place in biochemical research and treatment.
Interferons And Their Applications
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Author : P E Came
language : en
Publisher:
Release Date : 1983-11-01
Interferons And Their Applications written by P E Came and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-11-01 with Interferon categories.
Clinical Application Of Interferons And Their Inducers
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Author : Dale A. Stringfellow
language : en
Publisher: Marcel Dekker
Release Date : 1986
Clinical Application Of Interferons And Their Inducers written by Dale A. Stringfellow and has been published by Marcel Dekker this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.
The Interferons
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Author : Anthony Meager
language : en
Publisher: John Wiley & Sons
Release Date : 2006-08-21
The Interferons written by Anthony Meager and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-21 with Science categories.
At long last, the first book to cover all important areas of interferon science in one volume. Top scientists, including many pioneers in the field, highlight the role of interferons as research tools and as therapeutic agents in clinical applications. Edited by an experienced interferonologist, chapters include discussions of interferon genes, Type I, II and III IFNs, as well as their induction, production and purification, receptors actions, measuring IFN activities and anti-IFN antibodies, as well as the evolution of viral defense mechanisms. For immunologists, cancer researchers, medicinal chemists, cell biologists, developmental biologists and the pharmaceutical industry.
Interferons Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Interferons Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Interferons: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Interferons in a concise format. The editors have built Interferons: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Interferons in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Interferons: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Interferons A Primer
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Author : Robert Friedman
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Interferons A Primer written by Robert Friedman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Interferons: A Primer covers general information on interferon, including analysis, purification, production, properties, mechanism of action, and clinical uses. Organized into 10 chapters, the book starts with a short history of interferon’s discovery by Isaacs and Lindenmann, followed by topics on assays for interferon, such as factors affecting interferon assays and rapid biological assay. Chapters 3 to 6 discuss the purification, properties, production, antiviral action, and other functions of interferon. Chapters 7 and 8 examine the recovery from viral infection and clinical uses of interferon, with emphasis on treatment of human cancer. The concluding chapters focus on the application of interferon studies on two revolutionizing fields of biology, namely, the cloning of animal genes in microorganisms and the production of monoclonal antibodies. This book is intended for students, scientists, physicians, or educated laypersons who wish to know something about interferons, but do not plan carrying out research in this area.
Interferons
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Author : Carlo Aul
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Interferons written by Carlo Aul and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment. In the present volume, renowned international authors update the importance of interferons in various fields of internal medicine, dermatology, and urology. The book also contains a general introduction into the classification, structure, and mode of action of interferons. Further chapters discuss the range of side effects of these substances and point out possible focuses of further clinical interferon research.
Interferons
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Author : Thomas Merigan
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Interferons written by Thomas Merigan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Technology & Engineering categories.
Interferons documents the proceedings of a major international conference on Chemistry and Biology of Interferons: Relationship to Therapeutics held at Squaw Valley, California, in March 1982. The meeting was one of the 1982 UCLA Symposia on Molecular and Cellular Biology organized through the Molecular Biology Institute of the University of California at Los Angeles. The book is organized into four parts. Part I presents papers on recombinant DNA production of interferon. It includes studies on the synthesis of human immune interferon in E. coli and monkey cells; the expression of human ß interferon gene in heterologous cells; and the molecular activities of recombinant and hybrid leukocyte interferons. Part II deals with the biology of interferons, covering topics such as interferon production control process; the effect of interferon on cellular enzymes; and human amniotic interferon. Part III examines the factors relevant to clinical application of interferons, including structure-function studies with human interferon-gamma and on human alpha interferon. Part IV presents clinical studies of interferon, such as interferon a trials in human tumor diseases and interferon in renal transplant recipients.
Interferons
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Author : Joe H. Thomas
language : en
Publisher: Nova Science Publishers
Release Date : 2012
Interferons written by Joe H. Thomas and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Interferon categories.
Interferons are cytokines that are very important in regulating both innate and adaptive immune response. Of the two different types of interferons, Type I interferons are potent mediators of the innate immune response against viruses and cancer. Type II interferons, mainly IFN-y enhances T cell polarisation in the lymph nodes that result in their expansion. This book discusses the characterisation, mechanisms of action and clinical applications of interferons. Topics include interferon-gamma, oligodendrocyte injury and inflammatory demyelination; the role of IFN-y in oesophageal squamous cell carcinoma; interferons in multiple sclerosis; the effect of interferons on NK cell activity in HIV infection and tumour cell development; and understanding the mechanisms of interaction between serine proteases, serine protease receptors and interferons.
Advances In Interferon Type I Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Advances In Interferon Type I Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Advances in Interferon Type I Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Interferon Type I in a concise format. The editors have built Advances in Interferon Type I Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Interferon Type I in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Interferon Type I Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.