Introduction To Computational Proteomics

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Introduction To Computational Proteomics
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Author : Golan Yona
language : en
Publisher: CRC Press
Release Date : 2010-12-09
Introduction To Computational Proteomics written by Golan Yona and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-09 with Mathematics categories.
Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis, classification, and meta-organization. The book starts with the analysis of individual entities and works its way through the analysis of more complex entitie
Computational Methods For Mass Spectrometry Proteomics
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Author : Ingvar Eidhammer
language : en
Publisher: John Wiley & Sons
Release Date : 2008-02-28
Computational Methods For Mass Spectrometry Proteomics written by Ingvar Eidhammer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-28 with Medical categories.
Proteomics is the study of the subsets of proteins present in different parts of an organism and how they change with time and varying conditions. Mass spectrometry is the leading technology used in proteomics, and the field relies heavily on bioinformatics to process and analyze the acquired data. Since recent years have seen tremendous developments in instrumentation and proteomics-related bioinformatics, there is clearly a need for a solid introduction to the crossroads where proteomics and bioinformatics meet. Computational Methods for Mass Spectrometry Proteomics describes the different instruments and methodologies used in proteomics in a unified manner. The authors put an emphasis on the computational methods for the different phases of a proteomics analysis, but the underlying principles in protein chemistry and instrument technology are also described. The book is illustrated by a number of figures and examples, and contains exercises for the reader. Written in an accessible yet rigorous style, it is a valuable reference for both informaticians and biologists. Computational Methods for Mass Spectrometry Proteomics is suited for advanced undergraduate and graduate students of bioinformatics and molecular biology with an interest in proteomics. It also provides a good introduction and reference source for researchers new to proteomics, and for people who come into more peripheral contact with the field.
Computational And Statistical Methods For Protein Quantification By Mass Spectrometry
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Author : Ingvar Eidhammer
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-11
Computational And Statistical Methods For Protein Quantification By Mass Spectrometry written by Ingvar Eidhammer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-11 with Mathematics categories.
The definitive introduction to data analysis in quantitative proteomics This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author’s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers. Computational and Statistical Methods for Protein Quantification by Mass Spectrometry: Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs. Is illustrated by a large number of figures and examples as well as numerous exercises. Provides both clear and rigorous descriptions of methods and approaches. Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work. Features detailed discussions of both wet-lab approaches and statistical and computational methods. With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.
An Introduction To Computational Biochemistry
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Author : Tsai
language : en
Publisher: John Wiley & Sons
Release Date : 2007
An Introduction To Computational Biochemistry written by Tsai and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Market_Desc: · Primary: Students in Biochemistry, Bioinformatics, Biotechnology or Bioengineering, Computational Sciences, Chemistry, Molecular Biology· Secondary: Researchers in the above fields· Tertiary: Students and researchers in Computer science, Biomedical fields Special Features: · The book comprises of separate chapters that include problem sets and answers as well as an introduction, review of biological concepts, discussion of the programming and application, and key references· It also includes an appendix listing software suppliers· All programs cited in the book have been carefully chosen based on ease of installation and operation· Reviews the fundamental biochemical principles About The Book: This book provides a comprehensive introduction to biochemical principles and the skills required for applying computational tools to practical problems in biochemistry. It also details biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, as well as demonstrating the broad applications and versatility of computers for use in solving biochemical problems.
Computational Biology And Genome Informatics
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Author : Paul P Wang
language : en
Publisher: World Scientific
Release Date : 2003-02-19
Computational Biology And Genome Informatics written by Paul P Wang and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-02-19 with Computers categories.
This book contains articles written by experts on a wide range of topics that are associated with the analysis and management of biological information at the molecular level. It contains chapters on RNA and protein structure analysis, DNA computing, sequence mapping, genome comparison, gene expression data mining, metabolic network modeling, and phyloinformatics.The important work of some representative researchers in bioinformatics is brought together for the first time in one volume. The topic is treated in depth and is related to, where applicable, other emerging technologies such as data mining and visualization. The goal of the book is to introduce readers to the principle techniques of bioinformatics in the hope that they will build on them to make new discoveries of their own.
Introduction To Proteomics
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Author : Daniel Liebler
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-12-04
Introduction To Proteomics written by Daniel Liebler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-12-04 with Medical categories.
Daniel C. Liebler masterfully introduces the science of proteomics by spelling out the basics of how one analyzes proteins and proteomes, and just how these approaches are then employed to investigate their roles in living systems. He explains the key concepts of proteomics, how the analytical instrumentation works, what data mining and other software tools do, and how these tools can be integrated to study proteomes. Also discussed are how protein and peptide separation techniques are applied in proteomics, how mass spectrometry is used to identify proteins, and how data analysis software enables protein identification and the mapping of modifications. In addition, there are proteomic approaches for analyzing differential protein expression, characterizing proteomic diversity, and dissecting protein-protein interactions and networks.
Statistical Analysis Of Proteomics Metabolomics And Lipidomics Data Using Mass Spectrometry
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Author : Susmita Datta
language : en
Publisher: Springer
Release Date : 2016-12-22
Statistical Analysis Of Proteomics Metabolomics And Lipidomics Data Using Mass Spectrometry written by Susmita Datta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-22 with Medical categories.
This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies. Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.
Bioinformatics
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Author : Venkatarajan Mathura
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-10-11
Bioinformatics written by Venkatarajan Mathura and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-11 with Science categories.
Bioinformatics is an evolving field that is gaining popularity due to genomics, proteomics and other high-throughput biological methods. The function of bioinformatic scientists includes biological data storage, retrieval and in silico analysis of the results from large-scale experiments. This requires a grasp of knowledge mining algorithms, a thorough understanding of biological knowledge base, and the logical relationship of entities that describe a process or the system. Bioinformatics researchers are required to be trained in multidisciplinary fields of biology, mathematics and computer science. Currently the requirements are satisfied by ad hoc researchers who have specific skills in biology or mathematics/computer science. But the learning curve is steep and the time required to communicate using domain specific terms is becoming a major bottle neck in scientific productivity. This workbook provides hands-on experience which has been lacking for qualified bioinformatics researchers.
Computational Structural Biology Methods And Applications
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Author : Torsten Schwede
language : en
Publisher: World Scientific
Release Date : 2008-05-02
Computational Structural Biology Methods And Applications written by Torsten Schwede and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-02 with Science categories.
Computational structural biology has made tremendous progress over the last two decades, and this book provides a recent and broad overview of such computational methods in structural biology. It covers the impact of computational structural biology on protein structure prediction methods, macromolecular function and protein design, and key methods in drug discovery. It also addresses the computational challenges of experimental approaches in structural biology. In addition to reviewing the current state of computational structural biology, each chapter ends with a brief, visionary discussion on the future outlook, whereby the main challenges for the coming years are elucidated. Written by an international panel of expert contributors, this book can serve as a reference manual for students and practitioners alike.
Introduction To Proteomics
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Author : Agnieszka Kraj
language : en
Publisher: John Wiley & Sons
Release Date : 2008-10-20
Introduction To Proteomics written by Agnieszka Kraj and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-20 with Science categories.
Introduction to Proteomics is written by seasoned researchers with years of practical experience. In addition to comprehensive discussions of the basic concepts, techniques, and applications of the subject, the text also includes an extensive glossary and a chapter containing laboratory exercises and protocols. While mass spectrometry is central to proteomics, the book discusses all of the analytical techniques a student is likely to need when faced with real-world problems, such as sample preparation, chromatographic and electrophoretic separation, micro-total analysis systems, and bioinformatics.