Likelihood Bayesian And Mcmc Methods In Quantitative Genetics
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Likelihood Bayesian And Mcmc Methods In Quantitative Genetics
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Author : Daniel Sorensen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-22
Likelihood Bayesian And Mcmc Methods In Quantitative Genetics written by Daniel Sorensen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-22 with Science categories.
This book, suitable for numerate biologists and for applied statisticians, provides the foundations of likelihood, Bayesian and MCMC methods in the context of genetic analysis of quantitative traits. Although a number of excellent texts in these areas have become available in recent years, the basic ideas and tools are typically described in a technically demanding style and contain much more detail than necessary. Here, an effort has been made to relate biological to statistical parameters throughout, and the book includes extensive examples that illustrate the developing argument.
Quantitative Genetics
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Author : Armando Caballero
language : en
Publisher: Cambridge University Press
Release Date : 2020-04-23
Quantitative Genetics written by Armando Caballero and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-23 with Mathematics categories.
An up-to-date, accessible guide to the main concepts and applications of quantitative genetics.
Hydraulic And Civil Engineering Technology Vi
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Author : M. Yang
language : en
Publisher: IOS Press
Release Date : 2021-11-09
Hydraulic And Civil Engineering Technology Vi written by M. Yang and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-09 with Technology & Engineering categories.
New technologies, such as improved testing and physical modeling methods, together with numerical studies and other novel techniques, have led to many developments in the fields of hydraulic and civil engineering in recent years. This book presents proceedings from HCET 2021, the 6th International Technical Conference on Frontiers of Hydraulic and Civil Engineering Technology, held in Sanya, China, on 28 and 29 August 2021. The conference highlighted the latest advances, innovations and applications in the fields of hydraulic and civil engineering, and served as a platform to promote and celebrate interdisciplinary study. The book contains 89 papers, selected from 178 contributions and divided into 4 sections: Modern Civil Engineering; Water and Hydraulic Engineering; Environment Engineering and Sciences; and Transdisciplinary Engineering and Technology. Topics covered involve both theoretical and practical knowledge and understanding, primarily in the areas of hydraulics and water resource engineering, civil engineering, environmental engineering and sciences, transportation engineering, coastal and ocean engineering and transdisciplinary engineering and technology. The book, which presents a wealth of exciting ideas that will open novel research directions and foster multidisciplinary collaboration among specialists in various fields, will be of interest to all academics, researchers, practitioners and policymakers seeking to understand and tackle civil and hydraulic engineering challenges by adopting appropriate, sustainable, solutions.
Quantitative Genetics In The Wild
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Author : Anne Charmantier
language : en
Publisher: OUP Oxford
Release Date : 2014-04-03
Quantitative Genetics In The Wild written by Anne Charmantier and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-03 with Science categories.
Although the field of quantitative genetics - the study of the genetic basis of variation in quantitative characteristics such as body size, or reproductive success - is almost 100 years old, its application to the study of evolutionary processes in wild populations has expanded greatly over the last few decades. During this time, the use of 'wild quantitative genetics' has provided insights into a range of important questions in evolutionary ecology, ranging from studies conducting research in well-established fields such as life-history theory, behavioural ecology and sexual selection, to others addressing relatively new issues such as populations' responses to climate change or the process of senescence in natural environments. Across these fields, there is increasing appreciation of the need to quantify the genetic - rather than just the phenotypic - basis and diversity of key traits, the genetic basis of the associations between traits, and the interaction between these genetic effects and the environment. This research activity has been fuelled by methodological advances in both molecular genetics and statistics, as well as by exciting results emerging from laboratory studies of evolutionary quantitative genetics, and the increasing availability of suitable long-term datasets collected in natural populations, especially in animals. Quantitative Genetics in the Wild is the first book to synthesize the current level of knowledge in this exciting and rapidly-expanding area. This comprehensive volume also offers exciting perspectives for future studies in emerging areas, including the application of quantitative genetics to plants or arthropods, unraveling the molecular basis of variation in quantitative traits, or estimating non-additive genetic variance. Since this book deals with many fundamental questions in evolutionary ecology, it should be of interest to graduate, post-graduate students, and academics from a wide array of fields such as animal behaviour, ecology, evolution, and genetics.
Computational Methods For Genetics Of Complex Traits
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-11-10
Computational Methods For Genetics Of Complex Traits written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-10 with Science categories.
The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics reasearch. This thematic volume of Advances in Genetics looks at Computational Methods for Genetics of Complex traits. - Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models - Includes methods for testing with ethical, legal, and social implications - Critically analyzes future prospects
An Introduction To Bayesian Analysis
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Author : Jayanta K. Ghosh
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-03
An Introduction To Bayesian Analysis written by Jayanta K. Ghosh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-03 with Mathematics categories.
Though there are many recent additions to graduate-level introductory books on Bayesian analysis, none has quite our blend of theory, methods, and ap plications. We believe a beginning graduate student taking a Bayesian course or just trying to find out what it means to be a Bayesian ought to have some familiarity with all three aspects. More specialization can come later. Each of us has taught a course like this at Indian Statistical Institute or Purdue. In fact, at least partly, the book grew out of those courses. We would also like to refer to the review (Ghosh and Samanta (2002b)) that first made us think of writing a book. The book contains somewhat more material than can be covered in a single semester. We have done this intentionally, so that an instructor has some choice as to what to cover as well as which of the three aspects to emphasize. Such a choice is essential for the instructor. The topics include several results or methods that have not appeared in a graduate text before. In fact, the book can be used also as a second course in Bayesian analysis if the instructor supplies more details. Chapter 1 provides a quick review of classical statistical inference. Some knowledge of this is assumed when we compare different paradigms. Following this, an introduction to Bayesian inference is given in Chapter 2 emphasizing the need for the Bayesian approach to statistics.
Statistical Genetics
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Author : Benjamin Neale
language : en
Publisher: Garland Science
Release Date : 2007-11-30
Statistical Genetics written by Benjamin Neale and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-30 with Science categories.
Statistical Genetics is an advanced textbook focusing on conducting genome-wide linkage and association analysis in order to identify the genes responsible for complex behaviors and diseases. Starting with an introductory section on statistics and quantitative genetics, it covers both established and new methodologies, providing the genetic and statistical theory on which they are based. Each chapter is written by leading researchers, who give the reader the benefit of their experience with worked examples, study design, and sources of error. The text can be used in conjunction with an associated website (www.genemapping.org) that provides supplementary material and links to downloadable software.
Principles Of Statistical Genomics
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Author : Shizhong Xu
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-10
Principles Of Statistical Genomics written by Shizhong Xu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-10 with Science categories.
Statistical genomics is a rapidly developing field, with more and more people involved in this area. However, a lack of synthetic reference books and textbooks in statistical genomics has become a major hurdle on the development of the field. Although many books have been published recently in bioinformatics, most of them emphasize DNA sequence analysis under a deterministic approach. Principles of Statistical Genomics synthesizes the state-of-the-art statistical methodologies (stochastic approaches) applied to genome study. It facilitates understanding of the statistical models and methods behind the major bioinformatics software packages, which will help researchers choose the optimal algorithm to analyze their data and better interpret the results of their analyses. Understanding existing statistical models and algorithms assists researchers to develop improved statistical methods to extract maximum information from their data. Resourceful and easy to use, Principles of Statistical Genomics is a comprehensive reference for researchers and graduate students studying statistical genomics.
Handbook Of Epigenetics
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Author : Trygve O Tollefsbol
language : en
Publisher: Academic Press
Release Date : 2017-07-10
Handbook Of Epigenetics written by Trygve O Tollefsbol and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-10 with Science categories.
Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders. - Timely and comprehensive collection of fully up-to-date reviews on epigenetics that are organized into one volume and written by leading figures in the field - Covers the latest advances in many different areas of epigenetics, ranging from basic aspects, to technologies, to clinical medicine - Written at a verbal and technical level that can be understood by scientists and college students - Updated to include new epigenetic discoveries, newly approved therapeutics, and clinical trials
Handbook Of Statistical Genetics
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Author : David J. Balding
language : en
Publisher: John Wiley & Sons
Release Date : 2008-06-10
Handbook Of Statistical Genetics written by David J. Balding and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-10 with Science categories.
The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.