Linking Cellular Metabolism To Hematological Malignancies Volume Ii
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Linking Cellular Metabolism To Hematological Malignancies Volume Ii
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Author : Jian Yu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-18
Linking Cellular Metabolism To Hematological Malignancies Volume Ii written by Jian Yu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-18 with Medical categories.
Linking Cellular Metabolism To Hematological Malignancies
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Author : Jian Yu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-05
Linking Cellular Metabolism To Hematological Malignancies written by Jian Yu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-05 with Medical categories.
The Roles Of Oncogenic Phosphatase Kinase In Tumors
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Author : Lei Dong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-29
The Roles Of Oncogenic Phosphatase Kinase In Tumors written by Lei Dong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-29 with Science categories.
Double Edged Swords Important Factors Connecting Metabolic Disorders And Cancer Development From Basic Research To Translational Applications Volume Ii
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Author : Che-Pei Kung
language : en
Publisher: Frontiers Media SA
Release Date : 2024-12-30
Double Edged Swords Important Factors Connecting Metabolic Disorders And Cancer Development From Basic Research To Translational Applications Volume Ii written by Che-Pei Kung and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-30 with Medical categories.
The relationship between metabolic dysfunctions and cancer development has been continuously evolving, informed by research efforts in the fields of epidemiology, endocrinology, cancer biology, chemistry, genomics, metabolomics among others. Metabolism and cancer can intersect at the physiological level, where metabolic disorders and cancer malignancies occur as comorbid or mutually-promoting conditions; or at the molecular level, where metabolic alterations regulate tumorigenesis and oncogenic/tumor-suppressive pathways govern the onset of metabolic syndromes. The increasingly complex spider web connecting metabolic dysfunctions and cancer development reveals both distinctive and shared mechanisms underlying different disease indications. It also points to unique opportunities, either through repurposing existing tools or discovering new strategies, to develop targeted therapies against a wide variety of metabolic and cancerous diseases. In our previous Research Topic: Double-edged Swords: Genetic Factors That Influence The Pathogenesis of Both Metabolic Disease and Cancer , we highlighted ten genetic factors/mechanisms that influence the pathogenesis of both metabolic disease and cancer. The attention it generated to date ( >110,000 article views, >22,000 article downloads, >500 citations) signals a fast-growing interest from scientific communities of different disciplines. We aim to highlight more recent advances to inform a diverse audience working on basic and translational research.
Critical Complications In Pediatric Oncology And Hematopoietic Cell Transplant Volume Ii
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Author : Asya Agulnik
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-19
Critical Complications In Pediatric Oncology And Hematopoietic Cell Transplant Volume Ii written by Asya Agulnik and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-19 with Medical categories.
Pediatric oncology and hematopoietic cell transplant (HCT) patients with a critical illness are a particularly challenging population with a unique presentation, diagnosis, and management. One in every three to four children with cancer will require admission to the Pediatric Intensive Care Unit (PICU) during the course of their treatment. Providing optimum care for these patients involves dedicated multidisciplinary collaboration to provide timely and appropriate management. Onco-critical care is a growing field of expertise for the care of this high acuity patient population. Recent work in this field has focused on sepsis, respiratory complications, and multi-organ failure in HCT patients, demonstrating significantly higher morbidity and mortality compared to other critically ill pediatric patients. For the past decade, the HCT/oncology subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network has fostered both research and clinical collaborations between oncologists, transplanters, and critical care physicians with the goal to improve outcomes in critically ill oncology and HCT patients. Contributors to this Research Topic will be actively recruited from this network.
Targeting The Microenvironment Niche In Hematologic Malignancies
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Author : Cirino Botta
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-02
Targeting The Microenvironment Niche In Hematologic Malignancies written by Cirino Botta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-02 with Medical categories.
Circadian Rhythms And Metabolism
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Author : Etienne Challet
language : en
Publisher: Frontiers Media SA
Release Date : 2017-09-18
Circadian Rhythms And Metabolism written by Etienne Challet and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-18 with categories.
One of the major breakthroughs of the last decade in the understanding of energy homeostasis is the identification of a reciprocal control between circadian rhythmicity and cellular metabolism. Circadian rhythmicity is a fundamental endogenous process of almost every organism living on Earth. For instance, the alternation of hunger and satiety is not continuous over 24 h, but is instead structured in time along the light/dark cycle. In mammals, the temporal organization of metabolism, physiology and behavior around 24 h is controlled by a network of multiple cellular clocks, synchronized via neuronal and hormonal signals by a master clock located in the suprachiasmatic nuclei of the hypothalamus. This central circadian conductor in the brain is mainly reset by ambient light perceived by the retina, while secondary circadian clocks in other brain areas and peripheral organs can be reset by meal timing. Chronic disruption of circadian rhythms, as seen in human shift-workers (up to 20% of the active population), has been associated with the development of a number of adverse mental and metabolic conditions. Understanding of the functional links between circadian desynchronization and overall health in animal models and humans, however, is still scarce. Interactions between circadian clocks and metabolism can occur at different levels: the molecular clockwork, internal synchronization via neuro-hormonal signals, or external synchronization via photic or feeding cues. This Research Topic comprises a number of reviews as well as research and methods articles that feature recent advancements in the mechanisms linking circadian clocks with energy metabolism, and the pathophysiological implications of these interactions for metabolic health.
Real World Data And Real World Evidence In Hematologic Malignancies
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Author : Michele Malagola
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-10
Real World Data And Real World Evidence In Hematologic Malignancies written by Michele Malagola and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Medical categories.
Advances In Hematological Malignancies
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Author : Pier Paolo Piccaluga
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-12-11
Advances In Hematological Malignancies written by Pier Paolo Piccaluga and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-11 with Medical categories.
Explore the world of hematological malignancies with Advances in Hematological Malignancies, an insightful volume that explores the latest developments in blood cancer research and treatment. This book offers a comprehensive overview of acute leukemias, lymphomas—including those in HIV-positive individuals—and chronic myeloid leukemia (CML). This book provides a holistic understanding of these complex diseases. Key topics include breakthroughs in genetic profiling, targeted therapies, and the integration of immunotherapy, which are transforming patient care. Additionally, the book highlights the crucial role of nutrition in enhancing treatment outcomes and supporting patient well-being. Perfect for clinicians, researchers, and students, this volume is a valuable resource, offering practical insights and inspiring new approaches to tackling hematological malignancies. This will allow the reader to stay ahead in the dynamic field of hematology and provide knowledge to improve patient outcomes and drive future research.
Thomas Hematopoietic Cell Transplantation 2 Volume Set
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Author : Stephen J. Forman
language : en
Publisher: John Wiley & Sons
Release Date : 2016-12-27
Thomas Hematopoietic Cell Transplantation 2 Volume Set written by Stephen J. Forman and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-27 with Medical categories.
Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.