Machine Learning Methods For Multi Omics Data Integration
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Machine Learning Methods For Multi Omics Data Integration
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Author : Abedalrhman Alkhateeb
language : en
Publisher: Springer Nature
Release Date : 2023-11-13
Machine Learning Methods For Multi Omics Data Integration written by Abedalrhman Alkhateeb and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-13 with Computers categories.
The advancement of biomedical engineering has enabled the generation of multi-omics data by developing high-throughput technologies, such as next-generation sequencing, mass spectrometry, and microarrays. Large-scale data sets for multiple omics platforms, including genomics, transcriptomics, proteomics, and metabolomics, have become more accessible and cost-effective over time. Integrating multi-omics data has become increasingly important in many research fields, such as bioinformatics, genomics, and systems biology. This integration allows researchers to understand complex interactions between biological molecules and pathways. It enables us to comprehensively understand complex biological systems, leading to new insights into disease mechanisms, drug discovery, and personalized medicine. Still, integrating various heterogeneous data types into a single learning model also comes with challenges. In this regard, learning algorithms have been vital in analyzing and integratingthese large-scale heterogeneous data sets into one learning model. This book overviews the latest multi-omics technologies, machine learning techniques for data integration, and multi-omics databases for validation. It covers different types of learning for supervised and unsupervised learning techniques, including standard classifiers, deep learning, tensor factorization, ensemble learning, and clustering, among others. The book categorizes different levels of integrations, ranging from early, middle, or late-stage among multi-view models. The underlying models target different objectives, such as knowledge discovery, pattern recognition, disease-related biomarkers, and validation tools for multi-omics data. Finally, the book emphasizes practical applications and case studies, making it an essential resource for researchers and practitioners looking to apply machine learning to their multi-omics data sets. The book covers data preprocessing, feature selection, and model evaluation, providing readers with a practical guide to implementing machine learning techniques on various multi-omics data sets.
Learning To Classify Text Using Support Vector Machines
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Author : Thorsten Joachims
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Learning To Classify Text Using Support Vector Machines written by Thorsten Joachims and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Computers categories.
Based on ideas from Support Vector Machines (SVMs), Learning To Classify Text Using Support Vector Machines presents a new approach to generating text classifiers from examples. The approach combines high performance and efficiency with theoretical understanding and improved robustness. In particular, it is highly effective without greedy heuristic components. The SVM approach is computationally efficient in training and classification, and it comes with a learning theory that can guide real-world applications. Learning To Classify Text Using Support Vector Machines gives a complete and detailed description of the SVM approach to learning text classifiers, including training algorithms, transductive text classification, efficient performance estimation, and a statistical learning model of text classification. In addition, it includes an overview of the field of text classification, making it self-contained even for newcomers to the field. This book gives a concise introduction to SVMs for pattern recognition, and it includes a detailed description of how to formulate text-classification tasks for machine learning.
Kernel Based Data Fusion For Machine Learning
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Author : Shi Yu
language : en
Publisher: Springer
Release Date : 2011-03-29
Kernel Based Data Fusion For Machine Learning written by Shi Yu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-29 with Computers categories.
Data fusion problems arise frequently in many different fields. This book provides a specific introduction to data fusion problems using support vector machines. In the first part, this book begins with a brief survey of additive models and Rayleigh quotient objectives in machine learning, and then introduces kernel fusion as the additive expansion of support vector machines in the dual problem. The second part presents several novel kernel fusion algorithms and some real applications in supervised and unsupervised learning. The last part of the book substantiates the value of the proposed theories and algorithms in MerKator, an open software to identify disease relevant genes based on the integration of heterogeneous genomic data sources in multiple species. The topics presented in this book are meant for researchers or students who use support vector machines. Several topics addressed in the book may also be interesting to computational biologists who want to tackle data fusion challenges in real applications. The background required of the reader is a good knowledge of data mining, machine learning and linear algebra.
Machine Learning Advanced Dynamic Omics Data Analysis For Precision Medicine
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Author : Tao Zeng
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-30
Machine Learning Advanced Dynamic Omics Data Analysis For Precision Medicine written by Tao Zeng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-30 with categories.
Data Analytics In Bioinformatics
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Author : Rabinarayan Satpathy
language : en
Publisher: John Wiley & Sons
Release Date : 2021-01-20
Data Analytics In Bioinformatics written by Rabinarayan Satpathy and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-20 with Computers categories.
Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.
Machine Learning Techniques For Multimedia
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Author : Matthieu Cord
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-07
Machine Learning Techniques For Multimedia written by Matthieu Cord and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-07 with Computers categories.
Processing multimedia content has emerged as a key area for the application of machine learning techniques, where the objectives are to provide insight into the domain from which the data is drawn, and to organize that data and improve the performance of the processes manipulating it. Applying machine learning techniques to multimedia content involves special considerations – the data is typically of very high dimension, and the normal distinction between supervised and unsupervised techniques does not always apply. This book provides a comprehensive coverage of the most important machine learning techniques used and their application in this domain. Arising from the EU MUSCLE network, a program that drew together multidisciplinary teams with expertise in machine learning, pattern recognition, artificial intelligence, and image, video, text and crossmedia processing, the book first introduces the machine learning principles and techniques that are applied in multimedia data processing and analysis. The second part focuses on multimedia data processing applications, with chapters examining specific machine learning issues in domains such as image retrieval, biometrics, semantic labelling, mobile devices, and mining in text and music. This book will be suitable for practitioners, researchers and students engaged with machine learning in multimedia applications.
Computational Genomics With R
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Author : Altuna Akalin
language : en
Publisher: CRC Press
Release Date : 2020-12-16
Computational Genomics With R written by Altuna Akalin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-16 with Mathematics categories.
Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.
Data Management In Machine Learning Systems
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Author : Matthias Boehm
language : en
Publisher: Springer Nature
Release Date : 2022-05-31
Data Management In Machine Learning Systems written by Matthias Boehm and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-31 with Computers categories.
Large-scale data analytics using machine learning (ML) underpins many modern data-driven applications. ML systems provide means of specifying and executing these ML workloads in an efficient and scalable manner. Data management is at the heart of many ML systems due to data-driven application characteristics, data-centric workload characteristics, and system architectures inspired by classical data management techniques. In this book, we follow this data-centric view of ML systems and aim to provide a comprehensive overview of data management in ML systems for the end-to-end data science or ML lifecycle. We review multiple interconnected lines of work: (1) ML support in database (DB) systems, (2) DB-inspired ML systems, and (3) ML lifecycle systems. Covered topics include: in-database analytics via query generation and user-defined functions, factorized and statistical-relational learning; optimizing compilers for ML workloads; execution strategies and hardware accelerators;data access methods such as compression, partitioning and indexing; resource elasticity and cloud markets; as well as systems for data preparation for ML, model selection, model management, model debugging, and model serving. Given the rapidly evolving field, we strive for a balance between an up-to-date survey of ML systems, an overview of the underlying concepts and techniques, as well as pointers to open research questions. Hence, this book might serve as a starting point for both systems researchers and developers.
Machine Learning Techniques On Gene Function Prediction
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Author : Quan Zou
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-04
Machine Learning Techniques On Gene Function Prediction written by Quan Zou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-04 with categories.
Introduction To Machine Learning In The Cloud With Python
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Author : Pramod Gupta
language : en
Publisher: Springer Nature
Release Date : 2021-04-28
Introduction To Machine Learning In The Cloud With Python written by Pramod Gupta and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-28 with Technology & Engineering categories.
This book provides an introduction to machine learning and cloud computing, both from a conceptual level, along with their usage with underlying infrastructure. The authors emphasize fundamentals and best practices for using AI and ML in a dynamic infrastructure with cloud computing and high security, preparing readers to select and make use of appropriate techniques. Important topics are demonstrated using real applications and case studies.