Matrix Metalloproteinases In Health And Disease Sculpting The Human Body


Matrix Metalloproteinases In Health And Disease Sculpting The Human Body
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Matrix Metalloproteinases In Health And Disease Sculpting The Human Body


Matrix Metalloproteinases In Health And Disease Sculpting The Human Body
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Author : Constance E Brinckerhoff
language : en
Publisher: World Scientific
Release Date : 2017-05-05

Matrix Metalloproteinases In Health And Disease Sculpting The Human Body written by Constance E Brinckerhoff and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-05 with Science categories.


The biochemistry and cell biology of Matrix Metalloproteinases (MMPs) are not necessarily straightforward, but basic information on the history of these enzymes, their various functions that extend far beyond the cleaving of the extracellular matrix, and the complex mechanisms that control their expression are valuable to both scientists and clinicians. This volume summarizes the salient features and functions of MMPs and applies this information in a practical manner in order to understand how they contribute to normal physiology and pathology of selected diseases. Chapters by noted clinicians Jean-Michel Dayer, MD in rheumatology, Jian Cao, MD in oncology, and Peter Libby, MD in cardiology, represent important practical and clinically-oriented contributions.



The Role Of Matrix Metalloproteinase In Human Body Pathologies


The Role Of Matrix Metalloproteinase In Human Body Pathologies
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Author : Francesco Travascio
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-12-20

The Role Of Matrix Metalloproteinase In Human Body Pathologies written by Francesco Travascio and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-20 with Medical categories.


Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body.



Extracellular Matrix For Tissue Engineering And Biomaterials


Extracellular Matrix For Tissue Engineering And Biomaterials
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Author : Anna C. Berardi
language : en
Publisher: Springer
Release Date : 2018-04-13

Extracellular Matrix For Tissue Engineering And Biomaterials written by Anna C. Berardi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-13 with Science categories.


This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function, differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials – from scientists, chemists and biologists through physicists, bioengineers and clinicians.



Stem Cells In Aesthetic Procedures


Stem Cells In Aesthetic Procedures
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Author : Melvin A. Shiffman
language : en
Publisher: Springer
Release Date : 2014-07-21

Stem Cells In Aesthetic Procedures written by Melvin A. Shiffman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-21 with Medical categories.


Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed and the wide range of aesthetic procedures involving stem cell fat transfer are then described in detail. These procedures relate to the face, breast, buttocks, legs, hands, penis and Poland syndrome. In addition, potential risks and complications are identified. The book has been written by leading experts and will be an invaluable source of information for students, beginners and experienced surgeons in a range of specialties.



Jellyfish And Polyps


Jellyfish And Polyps
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Author : Antonella Leone
language : en
Publisher: MDPI
Release Date : 2020-11-20

Jellyfish And Polyps written by Antonella Leone and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Science categories.


This Special Issue of Marine Drugs gathers recent investigations on the proteomes, metabolomes, transcriptomes, and the associated microbiomes of marine jellyfish and polyps, including bioactivity studies of their compounds and more generally, on their biotechnological potential, witnessing the increasingly recognized importance of Cnidaria as a largely untapped Blue Growth resource for new drug discovery. These researches evoke the outstanding ecological importance of cnidarians in marine ecosystems worldwide, calling for a global monitoring and conservation of marine biodiversity, so that the biotechnological exploitation of marine living resources will be carried out to conserve and sustainably use the natural capital of the oceans.



Inflammation And Cancer


Inflammation And Cancer
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Author : Bharat B. Aggarwal
language : en
Publisher: Springer
Release Date : 2014-05-12

Inflammation And Cancer written by Bharat B. Aggarwal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.


This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.



Microglia In Health And Disease


Microglia In Health And Disease
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Author : Marie-Ève Tremblay
language : en
Publisher:
Release Date : 2014-10-31

Microglia In Health And Disease written by Marie-Ève Tremblay and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-31 with categories.




Signaling Pathways In Liver Diseases


Signaling Pathways In Liver Diseases
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Author : Jean-Francois Dufour
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-24

Signaling Pathways In Liver Diseases written by Jean-Francois Dufour and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-24 with Medical categories.


Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as: Autophagy Notch Pathway P13K/PTEN Signaling in Liver Diseases Sirtuins Hepcidin and Iron Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis Oxidative Stress and Signaling in the Liver. Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.



Textbook Of Clinical Embryology


Textbook Of Clinical Embryology
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Author : Kevin Coward
language : en
Publisher: Cambridge University Press
Release Date : 2013-10-31

Textbook Of Clinical Embryology written by Kevin Coward and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Medical categories.


The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.



Pelvic Floor Disorders


Pelvic Floor Disorders
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Author : Giulio Santoro
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-27

Pelvic Floor Disorders written by Giulio Santoro and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-27 with Medical categories.


Dramatic improvement in imaging techniques (3D ultrasonography, dynamic magnetic resonance) allows greater insight into the complex anatomy of the pelvic floor and its pathological modifications.Obstetrical events leading to fecal and urinary incontinence in women, the development of pelvic organ prolapse, and mechanism of voiding dysfunction and obstructed defecation can now be accurately assessed, which is fundamental for appropriate treatment decision making. This book is written for gynecologists, colorectal surgeons, urologists, radiologists, and gastroenterologists with a special interest in this field of medicine. It is also relevant to everyone who aspires to improve their understanding of the fundamental principles of pelvic floor disorders.