Mechanism And Genetic Susceptibility Of Neurological Disorders
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Mechanism And Genetic Susceptibility Of Neurological Disorders
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Author : Andleeb Khan
language : en
Publisher: Springer Nature
Release Date : 2024-03-27
Mechanism And Genetic Susceptibility Of Neurological Disorders written by Andleeb Khan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-27 with Science categories.
This book is about the "Mechanism and Genetic susceptibility of Neurological disorders. It is a comprehensive exploration, penned by esteemed authors, and offers a profound understanding of these enigmatic ailments, their progression, and the strategic approaches employed to mitigate their impact. In this book, readers will uncover a wealth of knowledge surrounding the mechanistic intricacies that underlie various neurological disorders. Through meticulous research and insightful analysis, the authors elucidate the inner workings of these conditions, shedding light on the mechanisms responsible for their onset and progression. The central themes of this book are the recognition of the genetic landscape governing neurological disorders. It emphasizes the role played by a diverse array of genes in the development and progression of these conditions, highlighting the multifaceted genetic susceptibility that underlies their manifestation.
Rosenberg S Molecular And Genetic Basis Of Neurological And Psychiatric Disease
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Author : Roger N. Rosenberg
language : en
Publisher: Elsevier
Release Date : 2014-10-28
Rosenberg S Molecular And Genetic Basis Of Neurological And Psychiatric Disease written by Roger N. Rosenberg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Science categories.
Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. - Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease - Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain - Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations
Advances In Understanding The Pathogenetic Mechanisms Of Neurodevelopmental Disorders And Neurodegenerative Disease The Environment As A Putative Risk Factor
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Author : Anna Maria Lavezzi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-05
Advances In Understanding The Pathogenetic Mechanisms Of Neurodevelopmental Disorders And Neurodegenerative Disease The Environment As A Putative Risk Factor written by Anna Maria Lavezzi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-05 with Medical categories.
Neurodevelopmental disorders are generally influenced by genetic as well as intrauterine and extrauterine factors that affect the fetal-maternal environment and/or brain development that continues after birth. Specific genetic polymorphisms may increase susceptibility to environmental factors that alter the trajectory of brain development via diverse molecular mechanisms. In particular, the pre- and post-natal exposure to neurotoxic metals, pesticides, persistent organic pollutants, and other chemicals is increasingly recognized as involved in the pathogenesis of neurodevelopmental disorders, such as autism, deficiency attention/hyperactivity disorders, neurodegenerative disorders such as Parkinson's and Alzheimer's disease, chronic multiple sclerosis, and even fetal and infant death, including SIUDS (Sudden Unexplained Intrauterine Death Syndrome) and SIDS (Sudden Infant Death Syndrome).
Handbook Of Animal Models In Neurological Disorders
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Author : Colin R Martin
language : en
Publisher: Elsevier
Release Date : 2022-11-29
Handbook Of Animal Models In Neurological Disorders written by Colin R Martin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-29 with Medical categories.
Handbook of Animal Models in Neurological Disorders will better readers' understanding of a large variety of animal models and their applicability in studying a number of neurological disorders. Featuring sections on brain injury, stroke and neuroinflammation, this volume discusses in detail the utility, success and pitfalls of multiple models for each condition. Multiple disorders are covered, ranging from neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS, to multiple sclerosis, headache, migraine, and others. With expert authors, this book has applicability for anyone pursuing neuroscience or biomedical research working to better understand, study and ultimately treat neurological dysfunction. - Summarizes animal models for a variety of neurological conditions - Contains chapter abstracts, key facts, a dictionary and a summary - Covers both neurodegenerative diseases and other neurological conditions - Compares and contrasts different models and experimental systems - Includes sections on Alzheimer's, Parkinson's, brain injury, migraine, multiple sclerosis, and more
Neurogenetics
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Author : Nicholas Wood
language : en
Publisher: Cambridge University Press
Release Date : 2012-04-12
Neurogenetics written by Nicholas Wood and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-12 with Medical categories.
A coherent, up-to-date overview of the rapidly advancing field of neurogenetics for neurologists of any level.
Endocrine Modulators Of Neurological Processes Potential Treatment Targets Of Pediatric Neurological Diseases
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Author : Hong Ni
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-26
Endocrine Modulators Of Neurological Processes Potential Treatment Targets Of Pediatric Neurological Diseases written by Hong Ni and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-26 with Science categories.
Cell Membrane Engineering For Advancing Cell Based And Nanotechnology Based Therapies
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Author : Zahid Hussain
language : en
Publisher: Springer Nature
Release Date : 2025-07-18
Cell Membrane Engineering For Advancing Cell Based And Nanotechnology Based Therapies written by Zahid Hussain and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-18 with Technology & Engineering categories.
The battle against complex diseases and tissue defects drives innovation in treatment and medical research. The cell membrane plays a fundamental role in biological processes and serves as a promising platform for diagnostic and therapeutic advancements due to its diverse receptors and ligands. Recent advances in bioengineering, synthetic biology, and biomimetic nanotechnology have enabled the development of engineered cell membrane-based platforms, including surface-engineered cells, extracellular vesicles, bacterial membrane vesicles, membrane-coated nanoparticles, and hybrid nanomaterials, offering improved therapeutic and diagnostic potential over their natural counterparts. This book provides a comprehensive exploration of essential cell surfaceome components, detailing state-of-the-art surface engineering strategies and advancements in engineered cells and membrane-based therapeutic nanoplatforms. It examines the transformative applications of these platforms in immune engineering, gastrointestinal disease management, cancer therapy, tissue engineering, circulating tumor cell capture, theranostics, and the treatment of neurodegenerative, inflammatory, and infectious diseases. Significant topics, many at the forefront of scientific research, are examined in depth, allowing academics, clinicians, and biomedical researchers to understand the latest advancements in cell membrane engineering and address unmet clinical needs. Furthermore, this interdisciplinary book is highly relevant to modern healthcare and provides instructional content for graduate students in chemical biology, pharmacology, biomaterials science, biomedical engineering, immune engineering, nanobiotechnology, regenerative medicine, and translational medicine. This book brings together pioneering research to inspire a broad scientific audience and drive innovation in disease monitoring, precision treatment, and biomedical applications.
Neuroendocrine Research In Health And Disease
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Author : Yu-Feng Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-05
Neuroendocrine Research In Health And Disease written by Yu-Feng Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-05 with categories.
Phytochemicals As Lead Compounds For New Drug Discovery
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Author : Chukwuebuka Egbuna
language : en
Publisher: Elsevier
Release Date : 2019-09-07
Phytochemicals As Lead Compounds For New Drug Discovery written by Chukwuebuka Egbuna and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-07 with Science categories.
Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. - Presents fundamental concepts and factors affecting choice for plant-based products - Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward - Highlights recent advances in computational-based drug discovery - Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance
Bradley And Daroff S Neurology In Clinical Practice E Book
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Author : Joseph Jankovic
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-03-23
Bradley And Daroff S Neurology In Clinical Practice E Book written by Joseph Jankovic and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-23 with Medical categories.
A practical, dynamic resource for practicing neurologists, clinicians and trainees, Bradley and Daroff's Neurology in Clinical Practice, Eighth Edition, offers a straightforward style, evidence-based information, and robust interactive content supplemented by treatment algorithms and images to keep you up to date with all that's current in this fast-changing field. This two-volume set is ideal for daily reference, featuring a unique organization by presenting symptom/sign and by specific disease entities—allowing you to access content in ways that mirror how you practice. More than 150 expert contributors, led by Drs. Joseph Jankovic, John C. Mazziotta, Scott L. Pomeroy, and Nancy J. Newman, provide up-to-date guidance that equips you to effectively diagnose and manage the full range of neurological disorders. - Covers all aspects of today's neurology in an easy-to-read, clinically relevant manner. - Allows for easy searches through an intuitive organization by both symptom and grouping of diseases. - Features new and expanded content on movement disorders, genetic and immunologic disorders, tropical neurology, neuro-ophthalmology and neuro-otology, palliative care, pediatric neurology, and new and emerging therapies. - Offers even more detailed videos that depict how neurological disorders manifest, including EEG and seizures, deep brain stimulation for PD and tremor, sleep disorders, movement disorders, ocular oscillations, EMG evaluation, cranial neuropathies, and disorders of upper and lower motor neurons, as well as other neurologic signs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.